Testing for HOXB13, BRCA1 and BCRA2 is usually done in patients with:
ANSWER
Prostate cancer
translocation for follicular lymphoma
ANSWER
t(14:18)
Translocation for prostate cancer
ANSWER
t(4;6)(q22;q15)
What genes would be screened in a follicular lymphoma?
ANSWER
TOX, BACH2, AFF3 and EBF1
What genes would be screened in a colorectal panel?
ANSWER
KRAS, BRAF, PIK3CA
What genes would be screened in a breast cancer panel?
ANSWER
HER2, ERBB2, BRCA1
1
, presence of the Factor V Leiden mutation
ANSWER
1691G>A
Deletion in the paternal chromosome 15: del(15)(q11q13)
ANSWER
Prader-willi syndrome.
Deletion in the maternal chromosome 15: del(15)(q11q13)
ANSWER
Angelman syndrome
In mantle cell lymphoma (MCL), this is the fusion gene created:
ANSWER
CCND1-IGH
Mutation in what gene is associated with Fragile X syndrome?
ANSWER
FMR1
Mantle cell lymphoma (MCL) is caused by what translocation?
ANSWER
t(11;14)
Mutation in this gene (Xp21) is associated
ANSWER
2
ANSWER
Prostate cancer
translocation for follicular lymphoma
ANSWER
t(14:18)
Translocation for prostate cancer
ANSWER
t(4;6)(q22;q15)
What genes would be screened in a follicular lymphoma?
ANSWER
TOX, BACH2, AFF3 and EBF1
What genes would be screened in a colorectal panel?
ANSWER
KRAS, BRAF, PIK3CA
What genes would be screened in a breast cancer panel?
ANSWER
HER2, ERBB2, BRCA1
1
, presence of the Factor V Leiden mutation
ANSWER
1691G>A
Deletion in the paternal chromosome 15: del(15)(q11q13)
ANSWER
Prader-willi syndrome.
Deletion in the maternal chromosome 15: del(15)(q11q13)
ANSWER
Angelman syndrome
In mantle cell lymphoma (MCL), this is the fusion gene created:
ANSWER
CCND1-IGH
Mutation in what gene is associated with Fragile X syndrome?
ANSWER
FMR1
Mantle cell lymphoma (MCL) is caused by what translocation?
ANSWER
t(11;14)
Mutation in this gene (Xp21) is associated
ANSWER
2
