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NSG 4100 – Advanced Medical Surgical Nursing: Comprehensive Practice Questions (2026 Edition)

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NSG 4100 – Advanced Medical Surgical Nursing: Comprehensive Practice Questions (2026 Edition)

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Exam 4 NSG 4100 – Advanced Medical-
Surgical
Nursing: Comprehensive Practice
Questions
(2026 Edition)
Introduction
Welcome to the NSG 4100 Exam 4 Comprehensive Practice Question Set, specifically
designed for nursing students preparing for advanced medical-surgical nursing assessments in
2026. This set contains 120 meticulously crafted questions in mixed formats—multiple-choice
(MCQs), select-all-that-apply (SATA), and short-CORRECT 100% DETAILED ANSR
questions—covering high-yield topics that are critical for success on Exam 4.

These questions are aligned with current evidence-based nursing practices and core
competencies, emphasizing both critical thinking and clinical decision-making. Students who
complete this set will develop a deeper understanding of complex patient care scenarios
encountered in acute and critical care settings.

Key Content Areas Covered:
• Neurological Emergencies: Stroke, traumatic brain injury, seizure management,
increased intracranial pressure (ICP), and meningitis.
• Cardiovascular Emergencies: Acute myocardial infarction, cardiogenic shock,
arrhythmias, heart failure, and hemodynamic monitoring.
• Respiratory Emergencies: ARDS, acute respiratory failure, mechanical ventilation
management, and prevention of ventilator-associated complications.
• Endocrine Emergencies: Diabetic ketoacidosis (DKA), hyperosmolar hyperglycemic
state (HHS), thyroid storm, and adrenal crisis.
• Renal and Electrolyte Disorders: Acute kidney injury, hyperkalemia, hyponatremia,
hypernatremia, and fluid-electrolyte management.
• Critical Care Nursing Skills: Prioritization, rapid assessment, airway management,
infection prevention, and patient safety.
• Pharmacology and Therapeutics: Emergency medications, IV therapy, titration
protocols, and monitoring for adverse effects.

Learning Objectives:
1. Enhance Critical Thinking: Apply knowledge to complex, real-world clinical scenarios.

, 2. Strengthen Clinical Decision-Making: Prioritize interventions and anticipate
complications in critically ill patients.
3. Test Knowledge Retention: Evaluate understanding of pathophysiology, pharmacology,
and evidence-based nursing interventions.
4. Prepare for Exam Success: Each question includes a rationale, explaining the correct
CORRECT 100% DETAILED ANSR and highlighting key nursing concepts




1. A patient is admitted with a suspected stroke. Which assessment finding is
most concerning?
A. Facial droop on one side
B. Slurred speech
C. Sudden severe headache
D. Mild dizziness

CORRECT 100% DETAILED ANSR: C. Sudden severe headache
Rationale: A sudden severe headache may indicate hemorrhagic stroke, which is life-threatening
and requires immediate intervention. Facial droop and slurred speech are concerning but may
indicate ischemic stroke.



2. SATA: Which are early signs of increased intracranial pressure (ICP)?

A. Headache
B. Vomiting
C. Confusio n
D. Bradycardia
E. Pupillary changes

CORRECT 100% DETAILED ANSR: A, B, C, E
Rationale: Early ICP manifests as headache, nausea/vomiting, confusion, and pupil changes.
Bradycardia is usually a late sign (Cushing’s triad).



3. A patient with TBI (traumatic brain injury) has unequal pupils and decreased
LOC. What is the nurse’s priority action?
A. Document findings
B. Notify the provider immediately
C. Administer pain medication

,D. Reposition the patient

CORRECT 100% DETAILED ANSR: B. Notify the provider immediately
Rationale: Unequal pupils and decreased LOC indicate possible herniation, a neurological
emergency.


4. Short CORRECT 100% DETAILED ANSR: Name two priority
assessments for a patient with suspected stroke.
CORRECT 100% DETAILED ANSR:

1. Neurological assessment (GCS, motor function, speech)
2. Vital signs, including blood pressure and oxygen saturation
Rationale: Rapid assessment identifies stroke type and guides urgent interventions.



5. A patient with suspected ischemic stroke is scheduled for tPA therapy.
Which intervention is priority?
A. Monitor for bleeding
B. Encourage oral fluids
C. Administer antihypertensives
D. Elevate legs

CORRECT 100% DETAILED ANSR: A. Monitor for bleeding
Rationale: tPA is a thrombolytic that increases bleeding risk; close monitoring is critical.



6. SATA: Which patients require airborne precautions?
A. Measles
B. TB
C. Influenza
D. Varicella E. MRSA

CORRECT 100% DETAILED ANSR: A, B, D
Rationale: Airborne precautions are for infections transmitted via tiny aerosolized particles.
Influenza is droplet; MRSA is contact.

, 7. A patient in ICU develops sudden hypotension, tachycardia, and cold, clammy
skin. What type of shock is most likely?
A. Hypovolemic
B. Cardiogenic
C. Distributive (septic)
D. Neurogenic

CORRECT 100% DETAILED ANSR: B. Cardiogenic
Rationale: Cardiogenic shock is due to heart failure; hypotension, tachycardia, and cold clammy
skin are classic signs. Hypovolemic shock may have similar signs but usually follows fluid loss.



8. Short CORRECT 100% DETAILED ANSR: List two nursing interventions
for cardiogenic shock.
CORRECT 100% DETAILED ANSR:

1. Administer prescribed vasoactive medications (e.g., dopamine, norepinephrine)
2. Monitor hemodynamic parameters and oxygen saturation
Rationale: Maintaining perfusion and oxygenation is critical to prevent organ failure.



9. SATA: Which are signs of right-sided heart failure?
A. Jugular vein distention
B. Peripheral edema
C. Crackles in lungs
D. Ascites
E. Dyspnea

CORRECT 100% DETAILED ANSR: A, B, D
Rationale: Right-sided HF causes systemic congestion (JVD, edema, ascites). Dyspnea and
crackles are more prominent in left-sided HF.



10. A patient with COPD on mechanical ventilation has a sudden drop in oxygen
saturation and absent breath sounds on the right. What is the nurse’s priority
action?
A. Reposition the patient
B. Notify the provider immediately

Table of contents

  1. 01 Exam 4 NSG 4100 – Advanced Medical-Surgical Nursing: Comprehensive Practice Questions (2026 Edition) 1
    1. Introduction 1

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