Questions |
Introduction to Pharmacology |
20 NCLEX-RN NGN Pharmacology MCQs
with Detailed Rationales | Nursing Exam
Study Guide
Question 1
Clinical Scenario
A 72-year-old woman is admitted with community-acquired
pneumonia. Her medical history includes hypertension, chronic kidney
disease stage 3, and osteoarthritis. During medication reconciliation,
the nurse notes that the patient has been taking several prescription
medications, an over-the-counter ibuprofen product daily, and an
herbal supplement purchased online. The provider is preparing to
prescribe an antibiotic.
Question Stem
Which nursing action is the highest priority before administering the
newly prescribed medication?
,A. Ask the patient when she last ate a meal.
B. Complete a comprehensive medication reconciliation, including over-
the-counter and herbal products.
C. Teach the patient about completing the full course of antibiotics.
D. Assess the patient's pain level before administering the medication.
Correct Answer
Correct Answer: B. Complete a comprehensive medication
reconciliation, including over-the-counter and herbal products.
Detailed Rationale
Medication reconciliation is a critical patient safety process that
identifies all prescription medications, over-the-counter (OTC) drugs,
vitamins, herbal supplements, and dietary products a patient is taking.
Older adults commonly use multiple medications, increasing the risk of
drug-drug and drug-herb interactions, duplicate therapies, adverse drug
reactions, and medication errors. Before initiating any new medication,
the nurse should verify the complete medication list to identify
potential contraindications or interactions that may require therapy
modification.
Option A is incorrect because food intake may influence medication
absorption for some drugs, but confirming the patient's complete
medication history is a greater priority before administering a new
medication.
Option C is incorrect because patient education is essential but should
occur after ensuring the medication is safe to administer.
,Option D is incorrect because pain assessment is appropriate in many
situations but is not directly related to preventing potentially harmful
medication interactions.
Medication reconciliation supports safe prescribing, especially in older
adults and patients with chronic diseases such as kidney impairment.
Nurses play a key role in identifying discrepancies before medication
administration, thereby reducing preventable adverse drug events.
Learning Objectives
After completing this question, the learner should be able to:
• Describe the purpose of medication reconciliation.
• Identify sources of medication interactions, including herbal
products.
• Prioritize nursing actions before administering a newly prescribed
medication.
Medication Safety Focus
Medication Reconciliation
Question 2
Clinical Scenario
A nurse is preparing to administer a scheduled dose of intravenous
morphine to a postoperative client. Before administration, the nurse
verifies the medication order, compares the medication label with the
medication administration record, confirms the client's identity using
, two identifiers, and assesses the client's pain level and respiratory
status.
Question Stem
Which pharmacology principle is demonstrated by completing these
assessments before medication administration?
A. Maximizing first-pass metabolism
B. Applying the rights of medication administration to reduce
medication errors
C. Increasing drug bioavailability
D. Preventing drug tolerance
Correct Answer
Correct Answer: B. Applying the rights of medication administration to
reduce medication errors
Detailed Rationale
Safe medication administration requires adherence to the rights of
medication administration, which include verifying the correct patient,
medication, dose, route, time, documentation, reason, response, and
patient education. Assessing pain confirms the indication for morphine,
while evaluating respiratory status identifies patients at increased risk
for opioid-induced respiratory depression before administration.
Option A is incorrect because first-pass metabolism refers to drug
metabolism in the liver after oral administration and is unrelated to IV
morphine.