N371 Platelet Disorders
(hematologic disorders
pt.2) Exam
(2026-2027)
** 100% Guaranteed Pass
** Expert-Verified Explanation
** Questions with Verified Answer
** Latest Edition | Updated
, platelets (thrombocytes) - circulate freely in blood in inactive form
- essential in control of bleeding
- collect at ites of injury to begin adhesion and temporary plug
- release mediators that activate clotting factors resulting in stable clot composed
of fibrin
stages of hemostasis 1. vascular response
2. platelet plug formation
3. development of fibrin clot
4. clot retraction
5. lysis of clot
vascular response stage 1 of hemostasis
- includes vasospasm and constriction
platelet plug formation Stage 2 of hemostasis
- turns plasma protein into fibrinogen into fibrin
development of fibrin clot stage 3 of hemostasis
- fibrin strands create a mesh network to form a clot
clot retraction stage 4 of hemostasis
lysis of clot stage 5 of hemostasis
intrinsic coagulation blood exposed to stimulus-damaged subendothelium
- contains PTT
- Factor 12, 11, 9, and 5
PTT, factor 12, 11, 10, 9 intrinsic pathway contains...
extrinsic coagulation outside the cell-tissue trauma
- contains PT/INR
- blood thinner works on this
PT/INR, factor 10 and 7 The extrinsic pathway contains...
common pathway the final clotting event occurs at the...
INS should be elevated if the patient is on a blood thinner than the...
bleeding disorders - thrombocytopenia
- immune thrombocytopenic purpura
- hemophilia
- von willebrand disease
thrombocytopenia defined as platelets under 150,000
- not a disease itself! (can be bone marrow dx or from heparin!)
- higher risk for bleeding
- decreased production or increased destruction of platelets
(hematologic disorders
pt.2) Exam
(2026-2027)
** 100% Guaranteed Pass
** Expert-Verified Explanation
** Questions with Verified Answer
** Latest Edition | Updated
, platelets (thrombocytes) - circulate freely in blood in inactive form
- essential in control of bleeding
- collect at ites of injury to begin adhesion and temporary plug
- release mediators that activate clotting factors resulting in stable clot composed
of fibrin
stages of hemostasis 1. vascular response
2. platelet plug formation
3. development of fibrin clot
4. clot retraction
5. lysis of clot
vascular response stage 1 of hemostasis
- includes vasospasm and constriction
platelet plug formation Stage 2 of hemostasis
- turns plasma protein into fibrinogen into fibrin
development of fibrin clot stage 3 of hemostasis
- fibrin strands create a mesh network to form a clot
clot retraction stage 4 of hemostasis
lysis of clot stage 5 of hemostasis
intrinsic coagulation blood exposed to stimulus-damaged subendothelium
- contains PTT
- Factor 12, 11, 9, and 5
PTT, factor 12, 11, 10, 9 intrinsic pathway contains...
extrinsic coagulation outside the cell-tissue trauma
- contains PT/INR
- blood thinner works on this
PT/INR, factor 10 and 7 The extrinsic pathway contains...
common pathway the final clotting event occurs at the...
INS should be elevated if the patient is on a blood thinner than the...
bleeding disorders - thrombocytopenia
- immune thrombocytopenic purpura
- hemophilia
- von willebrand disease
thrombocytopenia defined as platelets under 150,000
- not a disease itself! (can be bone marrow dx or from heparin!)
- higher risk for bleeding
- decreased production or increased destruction of platelets
