CMN 568 FINAL EXAM – FAMILY NURSE PRACTITIONER
(FNP) COMPREHENSIVE ASSESSMENT 2026/2027
UPDATE COMPLETE QUESTIONS WITH VERIFIED
CORRECT ANSWERS | ACTUAL QUESTIONS AND
CORRECT ANSWERS (LATEST 2026/2027 UPDATE) |
COMPLETE Q&A WITH VERIFIED ANSWERS AND
DETAILED RATIONALES | OBJECTIVE ASSESSMENT PREP
| A+ GRADED
Core Domains Covered:
• Cardiovascular Disorders
• Pulmonary Disorders
• Endocrine Disorders
• Gastrointestinal Disorders
• Neurological Disorders
• Musculoskeletal Disorders
• Renal and Genitourinary Disorders
• Infectious Diseases
• Women's Health
• Men's Health
• Pediatric and Adolescent Health
• Geriatric Health
• Mental Health and Behavioral Disorders
• Health Promotion and Disease Prevention
• Pharmacology and Prescribing
• Diagnostic Testing and Interpretation
,QUESTION 1
A 55-year-old woman with hypertension and diabetes presents for a routine
visit. Her blood pressure is 134/84 mmHg. According to ACC/AHA guidelines,
this blood pressure is classified as:
A. Normal
B. Elevated
C. Stage 1 hypertension
D. Stage 2 hypertension
Correct Answer: C. Stage 1 hypertension
RATIONALE: Stage 1 hypertension is defined as systolic 130–139 mmHg or
diastolic 80–89 mmHg. This patient's reading of 134/84 meets the criteria for
Stage 1 hypertension. Normal is <120/<80; Elevated is 120–129/<80; Stage 2
is ≥140/≥90.
QUESTION 2
A 62-year-old man with a 40-pack-year smoking history asks about cancer
screening. The USPSTF recommends annual low-dose CT for adults aged 50–
80 who have at least a ____ pack-year smoking history and currently smoke or
quit within the past 15 years.
A. 10
B. 20
C. 30
D. 40
Correct Answer: B. 20
RATIONALE: USPSTF guidelines recommend annual lung cancer screening
with low-dose CT for adults aged 50–80 years with a 20-pack-year smoking
history who currently smoke or have quit within the past 15 years. This
patient meets all criteria.
,QUESTION 3
A 48-year-old woman presents with fatigue, weight gain, cold intolerance, and
dry skin. Laboratory findings reveal TSH 8.5 mIU/L (normal 0.4–4.0) and free
T4 0.6 ng/dL (normal 0.8–1.8). Which is the MOST appropriate initial
treatment?
A. Levothyroxine 25 mcg daily
B. Levothyroxine 50 mcg daily
C. Methimazole 5 mg daily
D. Observation with repeat labs in 6 months
Correct Answer: B. Levothyroxine 50 mcg daily
RATIONALE: This patient has overt hypothyroidism with elevated TSH and
low free T4. Levothyroxine is the standard treatment. Starting dose for an
otherwise healthy patient without cardiac disease is approximately 1.6
mcg/kg/day (typically 50–100 mcg daily for an average adult). Observation is
inappropriate for overt hypothyroidism. Methimazole is used for
hyperthyroidism.
QUESTION 4
A 65-year-old man with a history of osteoarthritis presents with acute onset
of severe right knee pain, swelling, and erythema. He denies trauma. Joint
aspiration reveals needle-shaped, negatively birefringent crystals under
polarized light. What is the MOST likely diagnosis?
A. Osteoarthritis exacerbation
B. Gout
C. Pseudogout
D. Rheumatoid arthritis
Correct Answer: C. Pseudogout
RATIONALE: Pseudogout (calcium pyrophosphate deposition disease)
presents with acute monoarticular arthritis, most commonly affecting the
knee. Joint aspiration typically reveals rhomboid-shaped, positively
birefringent crystals; however, the key distinguishing feature is the presence
of calcium pyrophosphate crystals. Gout (urate crystals) shows needle-
, shaped, negatively birefringent crystals but is more common in the first MTP
joint.
QUESTION 5
A 72-year-old woman presents with progressive memory loss, difficulty with
daily activities, and personality changes over the past 2 years. Her Mini-
Mental State Examination (MMSE) score is 22/30. Which medication should
be considered FIRST-line for cognitive symptoms?
A. Donepezil
B. Memantine
C. Rivastigmine
D. Galantamine
Correct Answer: A. Donepezil
RATIONALE: Donepezil is a cholinesterase inhibitor commonly used as first-
line treatment for mild to moderate Alzheimer's disease. It works by
increasing acetylcholine levels in the brain. Memantine is typically used for
moderate to severe disease or in combination therapy. Rivastigmine and
galantamine are also options but not typically first-line.
QUESTION 6
A 35-year-old woman presents with intermittent epigastric pain, bloating, and
early satiety. Upper endoscopy reveals a 3 cm gastric ulcer. Biopsy shows H.
pylori organisms. What is the appropriate treatment regimen?
A. Omeprazole alone for 8 weeks
B. Triple therapy: Clarithromycin, Amoxicillin, Omeprazole
C. Sucralfate only
D. Antacids and lifestyle modification
Correct Answer: B. Triple therapy: Clarithromycin, Amoxicillin,
Omeprazole
RATIONALE: H. pylori-associated peptic ulcer disease requires eradication
therapy. Standard triple therapy includes two antibiotics (clarithromycin and
(FNP) COMPREHENSIVE ASSESSMENT 2026/2027
UPDATE COMPLETE QUESTIONS WITH VERIFIED
CORRECT ANSWERS | ACTUAL QUESTIONS AND
CORRECT ANSWERS (LATEST 2026/2027 UPDATE) |
COMPLETE Q&A WITH VERIFIED ANSWERS AND
DETAILED RATIONALES | OBJECTIVE ASSESSMENT PREP
| A+ GRADED
Core Domains Covered:
• Cardiovascular Disorders
• Pulmonary Disorders
• Endocrine Disorders
• Gastrointestinal Disorders
• Neurological Disorders
• Musculoskeletal Disorders
• Renal and Genitourinary Disorders
• Infectious Diseases
• Women's Health
• Men's Health
• Pediatric and Adolescent Health
• Geriatric Health
• Mental Health and Behavioral Disorders
• Health Promotion and Disease Prevention
• Pharmacology and Prescribing
• Diagnostic Testing and Interpretation
,QUESTION 1
A 55-year-old woman with hypertension and diabetes presents for a routine
visit. Her blood pressure is 134/84 mmHg. According to ACC/AHA guidelines,
this blood pressure is classified as:
A. Normal
B. Elevated
C. Stage 1 hypertension
D. Stage 2 hypertension
Correct Answer: C. Stage 1 hypertension
RATIONALE: Stage 1 hypertension is defined as systolic 130–139 mmHg or
diastolic 80–89 mmHg. This patient's reading of 134/84 meets the criteria for
Stage 1 hypertension. Normal is <120/<80; Elevated is 120–129/<80; Stage 2
is ≥140/≥90.
QUESTION 2
A 62-year-old man with a 40-pack-year smoking history asks about cancer
screening. The USPSTF recommends annual low-dose CT for adults aged 50–
80 who have at least a ____ pack-year smoking history and currently smoke or
quit within the past 15 years.
A. 10
B. 20
C. 30
D. 40
Correct Answer: B. 20
RATIONALE: USPSTF guidelines recommend annual lung cancer screening
with low-dose CT for adults aged 50–80 years with a 20-pack-year smoking
history who currently smoke or have quit within the past 15 years. This
patient meets all criteria.
,QUESTION 3
A 48-year-old woman presents with fatigue, weight gain, cold intolerance, and
dry skin. Laboratory findings reveal TSH 8.5 mIU/L (normal 0.4–4.0) and free
T4 0.6 ng/dL (normal 0.8–1.8). Which is the MOST appropriate initial
treatment?
A. Levothyroxine 25 mcg daily
B. Levothyroxine 50 mcg daily
C. Methimazole 5 mg daily
D. Observation with repeat labs in 6 months
Correct Answer: B. Levothyroxine 50 mcg daily
RATIONALE: This patient has overt hypothyroidism with elevated TSH and
low free T4. Levothyroxine is the standard treatment. Starting dose for an
otherwise healthy patient without cardiac disease is approximately 1.6
mcg/kg/day (typically 50–100 mcg daily for an average adult). Observation is
inappropriate for overt hypothyroidism. Methimazole is used for
hyperthyroidism.
QUESTION 4
A 65-year-old man with a history of osteoarthritis presents with acute onset
of severe right knee pain, swelling, and erythema. He denies trauma. Joint
aspiration reveals needle-shaped, negatively birefringent crystals under
polarized light. What is the MOST likely diagnosis?
A. Osteoarthritis exacerbation
B. Gout
C. Pseudogout
D. Rheumatoid arthritis
Correct Answer: C. Pseudogout
RATIONALE: Pseudogout (calcium pyrophosphate deposition disease)
presents with acute monoarticular arthritis, most commonly affecting the
knee. Joint aspiration typically reveals rhomboid-shaped, positively
birefringent crystals; however, the key distinguishing feature is the presence
of calcium pyrophosphate crystals. Gout (urate crystals) shows needle-
, shaped, negatively birefringent crystals but is more common in the first MTP
joint.
QUESTION 5
A 72-year-old woman presents with progressive memory loss, difficulty with
daily activities, and personality changes over the past 2 years. Her Mini-
Mental State Examination (MMSE) score is 22/30. Which medication should
be considered FIRST-line for cognitive symptoms?
A. Donepezil
B. Memantine
C. Rivastigmine
D. Galantamine
Correct Answer: A. Donepezil
RATIONALE: Donepezil is a cholinesterase inhibitor commonly used as first-
line treatment for mild to moderate Alzheimer's disease. It works by
increasing acetylcholine levels in the brain. Memantine is typically used for
moderate to severe disease or in combination therapy. Rivastigmine and
galantamine are also options but not typically first-line.
QUESTION 6
A 35-year-old woman presents with intermittent epigastric pain, bloating, and
early satiety. Upper endoscopy reveals a 3 cm gastric ulcer. Biopsy shows H.
pylori organisms. What is the appropriate treatment regimen?
A. Omeprazole alone for 8 weeks
B. Triple therapy: Clarithromycin, Amoxicillin, Omeprazole
C. Sucralfate only
D. Antacids and lifestyle modification
Correct Answer: B. Triple therapy: Clarithromycin, Amoxicillin,
Omeprazole
RATIONALE: H. pylori-associated peptic ulcer disease requires eradication
therapy. Standard triple therapy includes two antibiotics (clarithromycin and
