BIOS 252 Anatomy & Physiology Comprehensive
Exam Actual Exam 2026/2027 –
Complete Exam-Style Questions | 100% Verified –
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BIOS 252 Anatomy & Physiology II Comprehensive Practice Exam
SECTION 1: MUSCULAR SYSTEM
1. Which type of muscle is striated, voluntary, multinucleated, and attached to
bone?
• A) Cardiac muscle
• B) Smooth muscle
• C) Skeletal muscle
• D) Visceral muscle
Answer: C
Rationale: Skeletal muscle is striated, voluntary, and multinucleated. Cardiac
muscle is striated but involuntary, while smooth muscle is non-striated and
involuntary .
,2. The correct organizational hierarchy of skeletal muscle from smallest to
largest is:
• A) Muscle fascicle → Myofibril → Muscle fiber → Skeletal muscle
• B) Microfilaments → Myofibrils → Muscle fiber → Muscle fascicle →
Skeletal muscle
• C) Myofibril → Microfilaments → Muscle fascicle → Muscle fiber
• D) Skeletal muscle → Muscle fascicle → Muscle fiber → Myofibril
Answer: B
Rationale: The structural organization progresses from microfilaments (actin and
myosin) to myofibrils, then muscle fibers (cells), bundled into fascicles, and finally
the whole skeletal muscle .
3. The five properties of muscle tissue are:
• A) Excitability, contractility, elasticity, extensibility, conductivity
• B) Excitability, contractility, elasticity, conductivity, permeability
• C) Contractility, elasticity, conductivity, reactivity, extensibility
• D) Elasticity, conductivity, excitability, permeability, contractility
Answer: A
Rationale: All muscle tissues share excitability, conductivity, extensibility,
elasticity, and contractility .
4. The epimysium, perimysium, and endomysium are connective tissue layers
that:
• A) Surround the entire muscle, fascicles, and individual muscle fibers
respectively
• B) Surround individual muscle fibers, fascicles, and the entire muscle
respectively
• C) Are found only in cardiac muscle
, • D) Provide blood supply to the muscle
Answer: A
Rationale: The epimysium surrounds the entire muscle, the perimysium surrounds
fascicles, and the endomysium surrounds individual muscle fibers .
5. The functional contractile unit of a muscle fiber is the:
• A) Myofibril
• B) Sarcomere
• C) Myosin filament
• D) Actin filament
Answer: B
Rationale: The sarcomere, extending from Z-disc to Z-disc, is the functional
contractile unit .
6. During active muscle contraction, myosin heads bind to which protein?
• A) Dystrophin
• B) Actin
• C) Titin
• D) Troponin
Answer: B
Rationale: Myosin heads form cross-bridges by binding to actin during active
contraction .
7. Which molecule blocks the myosin-binding sites on actin in a relaxed muscle?
• A) Troponin
• B) Tropomyosin
• C) Calcium
, • D) ATP
Exam Actual Exam 2026/2027 –
Complete Exam-Style Questions | 100% Verified –
Pass Guaranteed – A+ Graded
BIOS 252 Anatomy & Physiology II Comprehensive Practice Exam
SECTION 1: MUSCULAR SYSTEM
1. Which type of muscle is striated, voluntary, multinucleated, and attached to
bone?
• A) Cardiac muscle
• B) Smooth muscle
• C) Skeletal muscle
• D) Visceral muscle
Answer: C
Rationale: Skeletal muscle is striated, voluntary, and multinucleated. Cardiac
muscle is striated but involuntary, while smooth muscle is non-striated and
involuntary .
,2. The correct organizational hierarchy of skeletal muscle from smallest to
largest is:
• A) Muscle fascicle → Myofibril → Muscle fiber → Skeletal muscle
• B) Microfilaments → Myofibrils → Muscle fiber → Muscle fascicle →
Skeletal muscle
• C) Myofibril → Microfilaments → Muscle fascicle → Muscle fiber
• D) Skeletal muscle → Muscle fascicle → Muscle fiber → Myofibril
Answer: B
Rationale: The structural organization progresses from microfilaments (actin and
myosin) to myofibrils, then muscle fibers (cells), bundled into fascicles, and finally
the whole skeletal muscle .
3. The five properties of muscle tissue are:
• A) Excitability, contractility, elasticity, extensibility, conductivity
• B) Excitability, contractility, elasticity, conductivity, permeability
• C) Contractility, elasticity, conductivity, reactivity, extensibility
• D) Elasticity, conductivity, excitability, permeability, contractility
Answer: A
Rationale: All muscle tissues share excitability, conductivity, extensibility,
elasticity, and contractility .
4. The epimysium, perimysium, and endomysium are connective tissue layers
that:
• A) Surround the entire muscle, fascicles, and individual muscle fibers
respectively
• B) Surround individual muscle fibers, fascicles, and the entire muscle
respectively
• C) Are found only in cardiac muscle
, • D) Provide blood supply to the muscle
Answer: A
Rationale: The epimysium surrounds the entire muscle, the perimysium surrounds
fascicles, and the endomysium surrounds individual muscle fibers .
5. The functional contractile unit of a muscle fiber is the:
• A) Myofibril
• B) Sarcomere
• C) Myosin filament
• D) Actin filament
Answer: B
Rationale: The sarcomere, extending from Z-disc to Z-disc, is the functional
contractile unit .
6. During active muscle contraction, myosin heads bind to which protein?
• A) Dystrophin
• B) Actin
• C) Titin
• D) Troponin
Answer: B
Rationale: Myosin heads form cross-bridges by binding to actin during active
contraction .
7. Which molecule blocks the myosin-binding sites on actin in a relaxed muscle?
• A) Troponin
• B) Tropomyosin
• C) Calcium
, • D) ATP
