multiple choice
Questions with 100% Correct Answers
and Rationales | Latest Update | Grade
A+ | 2026/2027
,Which of the following has dominant inheritance D.
a. wilson disease Huntington disease
b. PKU
C. Sickle Cell Disease Sadock B, Sadock V, Ruiz P: Kaplan & Sadock’s Comprehensive Textbook of
d. Huntington Disease Psychiatry, 10th ed, 2017 (volumes 1 and 2), Wolters Kluwer, ISBN-13:
e. Cri-Du-Chat 9781451100471, Volume I/ 2. Neuropsychiatry and Behavioral Neurology/ Ch.
2.6: Neuropsychiatric Aspects of Movement Disorders/ Primary Dementia
Syndromes with Parkinsonian Signs/ Huntington Disease/ Introduction and
Definition, p. 551.
Posttraumatic stress disorder has been most commonly B.
associated with reduced volume on MRI in which brain Hippocampus
region
a. thalamus a. Sadock BJ, Sadock VA, Ruiz P: Kaplan & Sadock's Synopsis of Psychiatry:
b. hippocampus Behavioral Sciences/Clinical Psychiatry, 11th ed, 2015, Wolters Kluwer, ISBN:
c. hypothalamus 978-1-60913-971-1, Ch. 11: Trauma- and Stressor-Related Disorders/ 11.1:
d. cerebral cortex Posttraumatic Stress Disorder and Acute Stress Disorder/ Etiology/ Biological
e. corpus callosum Factors/ Corticotropin-Releasing Factor and the HPA Axis, p. 439. | b.
O’Doherty DC, Chitty KM, Saddiqui S, et al: “A systematic review and meta-
analysis of magnetic resonance imaging measurement of structural volumes in
posttraumatic stress disorder.” Psychiatry Res. 2015 Apr 30;232(1):1-33. doi:
10.1016/j.pscychresns.2015.01.002. Epub 2015 Jan 30, Abstract p. 1; Results p. 8;
Discussion, p. 9.
A patient with Alzheimer dx struggles to take oral D.
acetylcholinesterase inhibitors due to severe nausea Rivastigmine (transdermal patch available)
and vomiting. Which of the following medications offers
an alternative route of administration that may improve Sadock B, Sadock V, Ruiz P: Kaplan & Sadock’s Comprehensive Textbook of
tolerability? Psychiatry, 10th ed, 2017 (volumes 1 and 2), Wolters Kluwer, ISBN-13:
a. tacrine 9781451100471, Ch. 34.15: Cholinesterase Inhibitors and Memantine/
b. donepezil Rivastigmine/ Pharmacological Actions/ Pharmacokinetics, p. 3045.
c. memantine
d. rivastigmine
e. galantamine
Evidence best supports use of acupuncture for which D.
of the following indications Pain management
a. anxiety
b. insomnia a. Sadock BJ, Sadock VA, Ruiz P: Kaplan & Sadock's Synopsis of Psychiatry:
c. depression Behavioral Sciences/Clinical Psychiatry, 11th ed, 2015, Wolters Kluwer, ISBN:
d. pain management 978-1-60913-971-1, Ch. 24: Complementary and Alternative Medicine in
e. smoking cessation Psychiatry/ National Center for Complementary Medicine and Alternative
Medicine, p. 791; Acupressure and Acupuncture, p. 792. | b. Smith CA, Armour
M, Lee MS, et al.: “Acupuncture for depression.” Cochrane Database of
Systematic Reviews. 2018 Mar 4;3:CD004046. doi:
10.1002/14651858.CD004046.pub4, Abstract/ Author’s Conclusions.
,Which of the following brain waves is most associated A.
with alertness in an adult waking EEG? Beta
a. beta
b. delta Sadock B, Sadock V, Ruiz P: Kaplan & Sadock’s Comprehensive Textbook of
c. theta Psychiatry, 10th ed, 2017 (volumes 1 and 2), Wolters Kluwer, ISBN-13:
d. alpha 9781451100471, Volume I/ Ch.1: Neural Sciences/ 1.15. Applied
e. gamma Electrophysiology/ EEG Characteristic Features/ Normal Intrinsic Frequencies/
Beta, p. 227.
Self report tolls adminitered prior to the session aid the B.
initial psychiatric interview by increasing the efficiency of the office visit.
a. promoting standardized tx plans
b. increasing the efficiency of the office visit Sadock B, Sadock V, Ruiz P: Kaplan & Sadock’s Comprehensive Textbook of
c. minimizing the risk of a pre-conceived diagnosis Psychiatry, 10th ed, 2017 (volumes 1 and 2), Wolters Kluwer, ISBN-13:
d. reducing the time needed to interview the patient 9781451100471, Ch. 7.1: Psychiatric Interview, History, and Mental Status
e. limiting false positive and false negative Examination of the Adult Patient/ General Principles/ Pre-Interview Contacts
identifications and Interactions/ Paragraphs 6-7, pp. 944-945.
Which of the following symptoms must be present to E.
make a diagnosis of manic episode Increased activity or energy
a. grandiosity
b. distractibility American Psychiatric Association: Diagnostic and Statistical Manual of Mental
c. flight of ideas Disorders – Fifth Edition DSM-5, 2013, ISBN 978-0-89042-554-1, Section II:
d. decreased need for sleep Diagnostic Criteria and Codes/ Bipolar and Related Disorders/ Bipolar I
e. increased activity or energy Disorder/ Diagnostic Criteria/ Manic Episode and Diagnostic Features.
a 44 year old patient presents with extreme fatigue and E. Adrenocorticotropic hormone stimulation test
depression. Physical examination reveals darkening of
skin and mucosa. Which of the following tests would This test is helpful in determining if the adrenal and pituitary glands are
most likely lead to the diagnosis normal. It is most often used when adrenal gland disorders, such as Addison's
a. Porphobilinogen disease or pituitary insufficiency, are suspected. Normal Values: An increase in
b. Vanillylmandelic acid cortisol after stimulation by ACTH is normal. Levenson J: The APP Textbook of
c. Thyroid Stimulating Hormone Psychosomatic Medicine and Consultation-Liaison Psychiatry, Third Edition,
d. 5-hydroxyindoleacetic acid 2018, APPI, ISBN-13: 978-1615371365, Ch. 21: Endocrine and Metabolic
e. adrenocorticotropic hormone stimulation test Disorders/ Adrenal Gland Disorders/ Adrenal Insufficiency: Addison’s Disease
and Corticotropin Deficiency
(https://doi.org/10.1176/appi.books.9781615371990.jl21).
, Buprenorphine is combined with Naloxone in oral C. Abuse potential
formulations to reduce which of the following
a. cravings Buprenorphine + Naloxone = suboxone
b. side effects
c. abuse potential Buprenorphine is a partial agonist (thus can cause immediate withdrawal in a pt
d. drug interactions currently taking opioids but can relieve withdrawal if a pt is already
e. lethality in overdose experiencing it) and an antagonist at the kappa opioid receptor
Naloxone is a mu receptor antagonist and can therefore block the effects of
buprenorphine but because it has poor sublingual bioavailability, it does not
interfere with buprenorphine's effects when used properly as it does have
good parenteral bioavailability
Thus if one tries to administer suboxone IV, naloxone will prevent any
rewarding effects from buprenorphine
Sadock B, Sadock V, Ruiz P: Kaplan & Sadock's Comprehensive Textbook of
Psychiatry, 10th ed, 2017, Wolters Kluwer, ISBN 13-978-1-451100471, Volume II/
34. Biological Therapies/ Ch. 34.24: Opioid Maintenance Treatments:
Methadone and Buprenorphine/ Buprenorphine/ Dosing, p. 3136.
Childhood trauma, which increases risk for depression E. FKBP5
and PTSD has been correlated with an increase in the
expression of which of the following genes The FKBP5 gene encodes a molecular co-chaperone of the glucocorticoid
a. AKT1 receptor complex, which modulates intracellular glucocorticoid signaling and
B. SERT plays an important role in homeostatic regulation of the stress response
C. FRM1
D. ApoE2 a. The AKT1 gene has also been implicated in schizophrenia by association
E. FKBP5 studies and decreased protein expression in the brains of schizophrenic
patients.
b.
c. Fragile X syndrome (FXS) is a genetic disorder. FXS is caused by changes in
a gene called Fragile X Messenger Ribonucleoprotein 1 (FMR1). FMR1 usually
makes a protein called FMRP that is needed for brain development. People
who have FXS do not make this protein.
Sadock B, Sadock V, Ruiz P: Kaplan & Sadock's Comprehensive Textbook of
Psychiatry, 10th ed, 2017, Wolters Kluwer, ISBN 13-978-1-451100471, Volume I/ 1.
Neural Sciences/ Ch. 1.25: Epigenetics in Psychiatry: The Promise for New
Biomarkers and Treatments/ Epigenetic Mechanisms in Psychiatric Illness/ Gene
by Environment Interaction Modulates FKBP5 Expression and the Risk for PTSD
/ Paragraph 1, p. 399.