CLINICAL PHARMACOLOGY
16TH EDITION
• AUTHOR(S)TODD W.
VANDERAH
TEST BANK
,Question 1
A nurse is teaching a community group about how medications
produce therapeutic effects. Which statement by a participant
demonstrates an accurate understanding of drug action?
A. "Every medication produces the same response in all
patients."
B. "A medication works by interacting with specific targets in
the body."
C. "Drug effects depend only on the dose that is prescribed."
D. "All medications permanently change body function."
Correct Answer: B
Rationale:
Many medications exert their effects by interacting with specific
biologic targets such as receptors, enzymes, ion channels, or
transport proteins. These interactions initiate or inhibit
physiologic processes that lead to therapeutic effects. Option A
is incorrect because genetic, physiologic, and environmental
differences influence individual responses. Option C is incorrect
because factors such as age, organ function, drug interactions,
and disease also affect drug response. Option D is incorrect
because most medications produce reversible rather than
permanent effects.
,Question 2
A nurse is reviewing a newly prescribed medication before
administration. Which factor has the greatest influence on
whether the medication is appropriate for a specific patient?
A. The color of the tablet
B. The medication's cost
C. The balance between expected therapeutic benefits and
potential risks
D. The manufacturer's advertising claims
Correct Answer: C
Rationale:
Medication therapy should be based on an individualized
assessment of anticipated benefits compared with potential
risks. Nurses evaluate indications, contraindications,
comorbidities, allergies, and monitoring requirements before
administration. Tablet color and advertising do not determine
clinical appropriateness. Cost may influence adherence but
should not be the primary determinant of whether therapy is
appropriate.
Question 3
, A patient asks why one medication can produce both desired
effects and adverse effects. Which response by the nurse is
most appropriate?
A. "Adverse effects occur only when the medication is
administered incorrectly."
B. "Therapeutic and adverse effects can result from the
medication acting on different tissues or receptors."
C. "Only medications with high doses produce adverse effects."
D. "Adverse effects indicate that the medication is ineffective."
Correct Answer: B
Rationale:
Many medications act on receptors or tissues throughout the
body. Desired effects occur at intended sites, whereas adverse
effects may result from actions at other sites or exaggerated
pharmacologic effects. Administration errors are only one
possible cause of adverse outcomes. Adverse effects may occur
at therapeutic doses and do not necessarily indicate treatment
failure.
Question 4
A nurse is caring for a patient receiving a medication with a
narrow therapeutic range. Which nursing action is the highest
priority?