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HESI A&P Version 2 Study Guide (Updated) – Complete Anatomy & Physiology Review, Practice Questions, and Nursing Entrance Exam Preparation

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This document provides an updated HESI Anatomy & Physiology Version 2 study guide featuring comprehensive review material and exam-style practice questions covering the body systems most commonly tested on the nursing entrance exam. It includes essential concepts related to the skeletal, muscular, cardiovascular, respiratory, nervous, endocrine, digestive, urinary, and reproductive systems, helping students reinforce key anatomy and physiology topics and prepare confidently for the HESI A2.

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HESI A&P VERSION 2 STUDY
GUIDE (UPDATED QUESTIONS
AND ANSWERS GRADED A+)
LATEST UPDATE 2026
What is a characteristic of viral herpes? - answer-skin eruption



When a boxer gets hit and has a deviated septum, what bone is it? - answer-vomer



A person who has damage to their ulnar nerve will have decreased sensation in? -
answer-arm, inability to adduct arms and fingers



Which bone does not articulate with any other bone? - answer-hyoid bone



What is a statement that best describes endocrine glands? - answer-they secrete
chemicals into the blood, growth, metabolism, sexual development & function



Diet is important because bones are storage places for? - answer-calcium and
phosphorus



Which organ is part of both the male reproductive system and the urinary system? -
answer-urethra



Ligaments provide which connection? - answer-bone to bone



Which structure conducts urine from the kidney to the urinary bladder? - answer-ureter



Anaerobic respiration can lead to a burning sensation caused by which molecule? -
answer-lactic acid

, As part of the negative feedback system, which type of cell is stimulated to resorb bone
matrix in response to a decrease in calcium in the blood? - answer-osteoclasts



Sweat on the skin's surface cools the body through which process? - answer-
evaporation



What are like cells grouped together called? - answer-tissue



The Pulse Point located behind the knee is Palpated over which artery? - answer-
popliteal



What occurs when the sympathetic nervous system is stimulated/increased? - answer-
cardiac output



What is the response of cells in the collecting tubules in nephrons when Antidiuretic
hormone (ADH) is secreted? - answer-H2O is re-absorbed from urinary filtrate



What is the function of thrombocytes (platelets)? - answer-blood clotting



Which structure carries oxygen to the cells? - answer-hemoglobin



Which gland is commonly known as the "Master Gland"? - answer-pituitary gland



What epidermal derivative is involved in temperature homeostasis? - answer-eccrine
gland (merocine/sweat gland)



Within which vessel does blood return from lungs? - answer-pulmonary vein



What internal structure of the ear is concerned with hearing? - answer-cochlea

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