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HESI RN Medical-Surgical Exam Review Comprehensive Practice Questions and Study Guide 2025/ 2026 NCLEX and HESI Prep Resource

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Prepare for the HESI RN Medical-Surgical examination with a comprehensive study guide featuring original practice questions, detailed answer rationales, and concept-focused review. Topics include cardiovascular, respiratory, neurological, gastrointestinal, endocrine, renal, and musculoskeletal nursing, along with prioritization, pharmacology, and clinical judgment. Designed to strengthen nursing knowledge, improve critical thinking, and build confidence for HESI, NCLEX, and medical-surgical nursing assessments in 2025/ 2026.

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Institution
HESI RN Med-Surg
Course
HESI RN Med-Surg

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Exam (20
https://www.stuvia.com/user/stuviaunHESI
Exam Sets, 1500+ Q & A, Newest-2024) RN HESI
Med-Surg
Med-Surg
Exam
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BANK Sets,
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1500+ Document
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HESI RN Med-Surg Exam (20 Exam Sets, 1500+ Q & A,
Newest-2024) / RN HESI Med-Surg Exam / Med-Surg HESI
RN Exam / Med-Surg RN HESI Exam / HESI RN Med Surg
Exam / RN HESI Med Surg Exam / Med Surg HESI RN
Exam |Complete Document for HESI Exam |
1. What instruction should the nurse include in the discharge teaching plan
of a client who had a cataract extraction today?
a. Sexual activities may be resumed upon return home
b. Light housekeeping is permitted but avoid heavy lifting
c. Use a metal eye shield on operative eye during the day
d. Administer eye ointment before applying eye drops

2. A male adult comes to the urgent care clinic 5 days after being diagnose
with influenza. He is short of breath, febrile, and coughing green colored
sputum. Which intervention should the nurse implement first?
a. Obtain a sputum sample for culture
b. Check his oxygen saturation level
c. Administer an oral antipyretic
d. Auscultate bilateral lung sound

3. An elder male client tells the nurse that he is loosing sleep because he
has to get up several times at night to go to the bathroom that he has
trouble starting his urinary stream and that he does not feel like his
bladder is ever completely empty. Which intervention should the nurse
implement?
a. collect a urine specimen for culture analysis
b. obtain a fingerstick blood glucose level
c. palpate the bladder above the symphysis pubis
d. review the client fluid intake

4. An adult client is admitted with diabetic ketoacidosis (DKA) and a urinary
tract infection (UTI) Prescriptions for intravenous antibiotics and insulin
infusion are initiated. Which serum laboratory value warrants the most
immediate intervention by the nurse?
a. blood ph of 7.30
b. glucose of 350 mg /dl
c. white blood cell count of 15000mm
d. potassium of 2.5 meq/l




Exam (20
HESI
Exam
RNSets,
Med-Surg
1500+Exam
Q & A,(20
Newest-2024)
Exam Sets, 1500+
RN HESI
Q &Med-Surg
A, Newest-2024)
https://www.stuvia.com/user/stuviaun
Exam BANK
RN HESI
Complete
Med-Surg
Document
Examfor
BANK
HESIComplete
Exam.docxhttps://www.stuvia.com/user/stuviaun
Document for HESI Exam.docxhttps://www.stuvia

,Exam (20
https://www.stuvia.com/user/stuviaunHESI
Exam Sets, 1500+ Q & A, Newest-2024) RN HESI
Med-Surg
Med-Surg
Exam
https://www.stuvia.com/user/stuviaun
Exam
(20 Exam
BANK Sets,
Complete
1500+ Document
Q & A, Newest-2024)
for HESI Exam.docxhttps://www.stuvia.com/user/stuviaun
RN HESI Med-Surg Exam BANK Complete Document f




5. A client with sickle cell anemia develops a fever during the last hour
ofadministration of a unit of packed red blood cell. When notifying the
healthcare provider what information should the nurse provide first using
the SBAR communication process?
a. explain specific reason for urgent notification
b. preface the report by stating the clients name and admitting
diagnosis
c. communicate the pre-transfusion temperatures
d. optain prn prescription for acetaminophen for fever 101f

6. An adult male client is admitted for pneumocystis carinil pneumonia
(PCP) secondary to aids. While hospitalize he receives IV pentamidine
isethionate therapy. In preparing this client for discharge what important
aspect regarding his medication therapy should the nurse explain?
a. AZT therapy must be stopped when IV aerosol pentamine is being
used.
b. IV pentamine will be given until oral pentamine can be tolerated
c. It will be necessary to continue prophylactic doses of IV or
aerosol pentamine every month
d. Iv pentamine may offer protection to others aids related conditions
such as kaposis sarcoma

7. A client subjective data includes dysuria, urgency, and urinary frequency.
What action should the nurse implement next?
a. collect a clean catch specimen
b. palpate the suprapubic region
c. instruct to wipe from front to back
d. inquire about recent sexual activity

8. A client tells the nurse that her biopsy results indicate that the cancer
cells are well differentiated How should the nurse respond?
a. offer the client reassurance that this information indicates that the
clients cancer cells are benign
b. explain that these tissue cells often respond more effectively to
radiation than to chemotherapy
c. ask the client in the healthcare provider has giving her any
information about the classification of her cancer
d. help the client make plans to begin inmediate treatment since her
cancer is likely to spread quickly

9. A client with a chronic kidney disease is treated on hemodialysis. During
the 1 treatment clients blood pressure drops from 150/90 to 80/30
Which action should the nurse take first?




Exam (20
HESI
Exam
RNSets,
Med-Surg
1500+Exam
Q & A,(20
Newest-2024)
Exam Sets, 1500+
RN HESI
Q &Med-Surg
A, Newest-2024)
https://www.stuvia.com/user/stuviaun
Exam BANK
RN HESI
Complete
Med-Surg
Document
Examfor
BANK
HESIComplete
Exam.docxhttps://www.stuvia.com/user/stuviaun
Document for HESI Exam.docxhttps://www.stuvia

,Exam (20
https://www.stuvia.com/user/stuviaunHESI
Exam Sets, 1500+ Q & A, Newest-2024) RN HESI
Med-Surg
Med-Surg
Exam
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Exam
(20 Exam
BANK Sets,
Complete
1500+ Document
Q & A, Newest-2024)
for HESI Exam.docxhttps://www.stuvia.com/user/stuviaun
RN HESI Med-Surg Exam BANK Complete Document f




a. monitor bp q45 minutes
b. lower the head of the chair and elevate feet
c. stop dialysis treatment
d. administer 5%albumin IV
10.A client with deep vain thrombosis (DVT) is receiving a continues
infusion of heparin sodium 25,000 unit in 5% dextrose injection 250ml.
The prescription indicates the dosage should be increase 900 units/hr.
The nurse should program the infusion pump to deliver how many
ml/hr?
=9

11.The nurse is obtaining the admission history for a client with suspected
peptic ulcer disease (PUD). Which subjective data reported by the client
supports this diagnosis?
a. upper mid abdominal gnawing and burning pain
b. severe abdominal cramps and diarrhea after eating spicy foods
c. marked loss of weight and appetite over the last few months
d. use of chewable and liquid antacids for indigestion


12.The nurse is providing preoperative education for a jewish client
schedule to receive a xenograft graft to promote burn healing. Which
information should the nurse provide this client?
a. the xenograft is taken from nonhuman sources
b. grafting increases the risk for bacterial infection
c. as the burn heals the graft permanently attaches
d. grafts are later removed by debriding procedure


13.A client who took a camping vacation two weeks ago in a country with a
tropical climate comes to the clinic describing vague symptoms and
diarrhea for the past week. Which finding is most important for the nurse
to report?
a. jaundice sclera
b. intestinal cramping
c. weakness and fatigue
d. weight loss


14.During a home visit the nurse assesses the skin of a client with eczema
who reports than an exacerbation of symptoms has occurred during the
last week. Which information is most useful in determining the possible
cause of the symptoms?
a. an old friend with eczema came for visit
b. recently received an influenza immunization




Exam (20
HESI
Exam
RNSets,
Med-Surg
1500+Exam
Q & A,(20
Newest-2024)
Exam Sets, 1500+
RN HESI
Q &Med-Surg
A, Newest-2024)
https://www.stuvia.com/user/stuviaun
Exam BANK
RN HESI
Complete
Med-Surg
Document
Examfor
BANK
HESIComplete
Exam.docxhttps://www.stuvia.com/user/stuviaun
Document for HESI Exam.docxhttps://www.stuvia

,Exam (20
https://www.stuvia.com/user/stuviaunHESI
Exam Sets, 1500+ Q & A, Newest-2024) RN HESI
Med-Surg
Med-Surg
Exam
https://www.stuvia.com/user/stuviaun
Exam
(20 Exam
BANK Sets,
Complete
1500+ Document
Q & A, Newest-2024)
for HESI Exam.docxhttps://www.stuvia.com/user/stuviaun
RN HESI Med-Surg Exam BANK Complete Document f




c. corticosteroid cream was applied to eczema
d. a grandson and his new dog recently visited
15.When explaining dietary guidelines to a client with acute
glomerulonephritis (AGN) which instruction should the nurse include in
the dietary teaching?
a. select a protein rich food daily
b. restrict sodium intake
c. eat high potassium foods
d. Avoid foods high in carbohydrate

16.A male client who is 24hr post operative for an exploratory laparoctomy
complains that he is starving because he has had no real food since
before surgery. Prior to advancing his diet which intervention should the
nurse implememt?
a. discontinue intravenous therapy
b. Assess for abdominal distension and tenderness
c. Obtain a prescription for a diet change
d. Auscultate bowel sound in all four quadrants

17.A client diagnose with stable angina secondary to ischemic heart disease
has a prescription for sublingual (SL) nitroglycerin (NTG). The nurse
should tell the client to follow which instructions if chest pain is not
relieved after taking 3 NTG tables 5 min apart?
a. drive to the nearest emergency department
b. take another NTG SL tablet and lie down until angina subsides
c. call primary healthcare provider
d. call 911 pain is unrelieved and chew a tablet of aspirin 325mg

18.After taking orlistat (Xenical) for one week a femela client tells the home
health nurse that she is experiencing increasingly frequent oily stools and
flatus. What action should the nurse take?
a. obtain stool specimen to evaluate for occult blood and fat content
b. instruct the client to increase her intake of saturated fats over the
next week
c. ask the client to describe her dietary intake history for the last
several days
d. advice the client to stop taking the drug and contact the healthcare
provider

19.Two days after an abscess of the chin was drained the client returns to
the clinic with fever chills and a maculopapular rash with pruritis. The
client has taken an oral antibiotic and cleansed the wound today with
provide iodine (Betadine) solution. Which intervention should the nurse
implement first?




Exam (20
HESI
Exam
RNSets,
Med-Surg
1500+Exam
Q & A,(20
Newest-2024)
Exam Sets, 1500+
RN HESI
Q &Med-Surg
A, Newest-2024)
https://www.stuvia.com/user/stuviaun
Exam BANK
RN HESI
Complete
Med-Surg
Document
Examfor
BANK
HESIComplete
Exam.docxhttps://www.stuvia.com/user/stuviaun
Document for HESI Exam.docxhttps://www.stuvia

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Institution
HESI RN Med-Surg
Course
HESI RN Med-Surg

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Uploaded on
June 30, 2026
Number of pages
125
Written in
2025/2026
Type
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Contains
Questions & answers

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