MCCQE Part I (MCCQE1) Medical Knowledge Exam 2026 |
Questions & Verified Answers | Comprehensive Board Review
1. A 45-year-old patient with a family history of diabetes presents for a
routine check-up. What screening test would be most appropriate for
this patient?
Complete blood count
Urine test for glucose
Lipid panel
Fasting plasma glucose test
2. Which race do fibroid tumors most often occur in?
Non-Hispanic White
Hispanic
African American
Italian
3. Describe the significance of adhering to the maximum dosage of
acetaminophen for both children and adults.
Adhering to the maximum dosage of acetaminophen is crucial
to prevent liver damage and ensure safe use.
The maximum dosage is the same for all age groups regardless
of weight.
The maximum dosage is only a guideline and can be exceeded if
necessary.
Acetaminophen has no side effects if taken in higher doses.
4. A 25-year-old woman presents with a Pap smear result indicating Low-
Grade Squamous Intraepithelial Lesion (LSIL). What is the most
, appropriate next step in her management?
Refer for colposcopy immediately.
Schedule a repeat Pap smear in 12 months.
Perform a biopsy right away.
Advise her to return only if she has symptoms.
5. Describe how Finasteride affects PSA levels in patients and its relevance
in prostate health.
Finasteride lowers PSA levels by reducing the size of the
prostate, which is important for monitoring prostate health.
Finasteride increases PSA levels by stimulating prostate growth,
indicating a higher risk of cancer.
Finasteride decreases testosterone levels, which directly lowers
PSA production.
Finasteride has no effect on PSA levels and is used solely for hair
loss treatment.
6. Describe the primary focus of treatment for fibrocystic changes of the
breast.
The primary focus is to administer hormone replacement therapy.
The primary focus is to eliminate the cysts surgically.
The primary focus is to prevent breast cancer.
The primary focus of treatment is to alleviate symptoms and
provide supportive care.
7. Describe how chickenpox can lead to complications in pediatric
patients.
Chickenpox can lead to complications such as bacterial
, infections of the skin due to scratching and secondary
infections.
Chickenpox primarily affects adults and does not lead to
complications in children.
Chickenpox complications are only related to respiratory issues.
Chickenpox does not have any long-term complications.
8. A 30-year-old female patient with a history of chest radiotherapy for
Hodgkin's lymphoma presents for a routine check-up. What screening
protocol should be discussed with her?
Annual mammography starting at age 30
Biannual chest X-rays starting immediately
No screening is necessary until age 40
MRI of the breast every two years
9. If a patient presents with a rash on the trunk and has a history of recent
sexual activity, what condition should be considered in the differential
diagnosis?
Contact dermatitis
Eczema
Psoriasis
Secondary syphilis
10. What is the primary treatment approach for Polyarteritis Nodosa
(PAN)?
Surgery
Corticosteroids
Chemotherapy
, Antibiotics
11. What is the maximum daily dose of acetaminophen for adults?
2000 mg
5000 mg
3000 mg
4000 mg
12. What is the primary test used to screen for diabetes?
Hemoglobin A1c test
Fasting plasma glucose test
Oral glucose tolerance test
Random plasma glucose test
13. What is the recommended tetanus prophylaxis for a clean wound if the
patient's vaccination history shows fewer than 3 doses?
Administer a booster dose of tetanus toxoid only.
No treatment is necessary.
Administer only tetanus immunoglobulin.
Administer tetanus toxoid and consider tetanus
immunoglobulin.
14. What is the primary method used to diagnose malaria?
CT scan
Urine test
MRI
Questions & Verified Answers | Comprehensive Board Review
1. A 45-year-old patient with a family history of diabetes presents for a
routine check-up. What screening test would be most appropriate for
this patient?
Complete blood count
Urine test for glucose
Lipid panel
Fasting plasma glucose test
2. Which race do fibroid tumors most often occur in?
Non-Hispanic White
Hispanic
African American
Italian
3. Describe the significance of adhering to the maximum dosage of
acetaminophen for both children and adults.
Adhering to the maximum dosage of acetaminophen is crucial
to prevent liver damage and ensure safe use.
The maximum dosage is the same for all age groups regardless
of weight.
The maximum dosage is only a guideline and can be exceeded if
necessary.
Acetaminophen has no side effects if taken in higher doses.
4. A 25-year-old woman presents with a Pap smear result indicating Low-
Grade Squamous Intraepithelial Lesion (LSIL). What is the most
, appropriate next step in her management?
Refer for colposcopy immediately.
Schedule a repeat Pap smear in 12 months.
Perform a biopsy right away.
Advise her to return only if she has symptoms.
5. Describe how Finasteride affects PSA levels in patients and its relevance
in prostate health.
Finasteride lowers PSA levels by reducing the size of the
prostate, which is important for monitoring prostate health.
Finasteride increases PSA levels by stimulating prostate growth,
indicating a higher risk of cancer.
Finasteride decreases testosterone levels, which directly lowers
PSA production.
Finasteride has no effect on PSA levels and is used solely for hair
loss treatment.
6. Describe the primary focus of treatment for fibrocystic changes of the
breast.
The primary focus is to administer hormone replacement therapy.
The primary focus is to eliminate the cysts surgically.
The primary focus is to prevent breast cancer.
The primary focus of treatment is to alleviate symptoms and
provide supportive care.
7. Describe how chickenpox can lead to complications in pediatric
patients.
Chickenpox can lead to complications such as bacterial
, infections of the skin due to scratching and secondary
infections.
Chickenpox primarily affects adults and does not lead to
complications in children.
Chickenpox complications are only related to respiratory issues.
Chickenpox does not have any long-term complications.
8. A 30-year-old female patient with a history of chest radiotherapy for
Hodgkin's lymphoma presents for a routine check-up. What screening
protocol should be discussed with her?
Annual mammography starting at age 30
Biannual chest X-rays starting immediately
No screening is necessary until age 40
MRI of the breast every two years
9. If a patient presents with a rash on the trunk and has a history of recent
sexual activity, what condition should be considered in the differential
diagnosis?
Contact dermatitis
Eczema
Psoriasis
Secondary syphilis
10. What is the primary treatment approach for Polyarteritis Nodosa
(PAN)?
Surgery
Corticosteroids
Chemotherapy
, Antibiotics
11. What is the maximum daily dose of acetaminophen for adults?
2000 mg
5000 mg
3000 mg
4000 mg
12. What is the primary test used to screen for diabetes?
Hemoglobin A1c test
Fasting plasma glucose test
Oral glucose tolerance test
Random plasma glucose test
13. What is the recommended tetanus prophylaxis for a clean wound if the
patient's vaccination history shows fewer than 3 doses?
Administer a booster dose of tetanus toxoid only.
No treatment is necessary.
Administer only tetanus immunoglobulin.
Administer tetanus toxoid and consider tetanus
immunoglobulin.
14. What is the primary method used to diagnose malaria?
CT scan
Urine test
MRI
