Lehne's Pharmacology for Nursing
Care
12th Edition
• Author(s)Jacqueline Rosenjack
Burchum; Laura D. Rosenthal
,TEST BANK
Question 1 (MCQ)
Clinical Scenario
A nurse is teaching newly hired graduate nurses about
pharmacology. During the session, one graduate asks why two
patients receiving the same dose of the same medication can
experience different therapeutic outcomes.
Question
Which explanation by the nurse is most accurate?
Options
A. Drug effects are identical because medications are
standardized.
B. Drug response is determined solely by the prescribed dose.
C. Individual patient characteristics influence pharmacologic
responses.
D. Generic medications produce weaker responses than brand-
name medications.
Correct Answer
,C. Individual patient characteristics influence pharmacologic
responses.
Detailed Rationale
Drug response varies among individuals because pharmacologic
effects are influenced by age, genetics, organ function,
concurrent illnesses, drug interactions, receptor sensitivity, and
adherence. Pharmacotherapy is therefore individualized to
maximize therapeutic benefit while minimizing toxicity.
Understanding variability helps nurses anticipate differing
responses even when identical doses are prescribed.
Incorrect Option Analysis
A
Why Incorrect
Drug effects are not identical across patients.
Common Misconception
Standardized medications guarantee identical outcomes.
Medication Safety Risk
Failure to monitor individualized responses.
Nursing Consideration
, Assess therapeutic effectiveness in every patient.
B
Why Incorrect
Dose is only one determinant of response.
Common Misconception
Higher doses always produce stronger desired effects.
Medication Safety Risk
Potential overdose or toxicity.
Nursing Consideration
Evaluate patient-specific factors before administration.
D
Why Incorrect
FDA-approved generic medications are therapeutically
equivalent.
Common Misconception
Generic drugs are inferior.
Medication Safety Risk
Care
12th Edition
• Author(s)Jacqueline Rosenjack
Burchum; Laura D. Rosenthal
,TEST BANK
Question 1 (MCQ)
Clinical Scenario
A nurse is teaching newly hired graduate nurses about
pharmacology. During the session, one graduate asks why two
patients receiving the same dose of the same medication can
experience different therapeutic outcomes.
Question
Which explanation by the nurse is most accurate?
Options
A. Drug effects are identical because medications are
standardized.
B. Drug response is determined solely by the prescribed dose.
C. Individual patient characteristics influence pharmacologic
responses.
D. Generic medications produce weaker responses than brand-
name medications.
Correct Answer
,C. Individual patient characteristics influence pharmacologic
responses.
Detailed Rationale
Drug response varies among individuals because pharmacologic
effects are influenced by age, genetics, organ function,
concurrent illnesses, drug interactions, receptor sensitivity, and
adherence. Pharmacotherapy is therefore individualized to
maximize therapeutic benefit while minimizing toxicity.
Understanding variability helps nurses anticipate differing
responses even when identical doses are prescribed.
Incorrect Option Analysis
A
Why Incorrect
Drug effects are not identical across patients.
Common Misconception
Standardized medications guarantee identical outcomes.
Medication Safety Risk
Failure to monitor individualized responses.
Nursing Consideration
, Assess therapeutic effectiveness in every patient.
B
Why Incorrect
Dose is only one determinant of response.
Common Misconception
Higher doses always produce stronger desired effects.
Medication Safety Risk
Potential overdose or toxicity.
Nursing Consideration
Evaluate patient-specific factors before administration.
D
Why Incorrect
FDA-approved generic medications are therapeutically
equivalent.
Common Misconception
Generic drugs are inferior.
Medication Safety Risk
