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Microbiology 4000 Chapter 12 – Viruses Questions and Answers.

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Virus - Answer A no cellular particle containing a genome that can replicate only inside a host cell Bacteriophage - Answer A virus that infects bacteria Virion - Answer a complete virus particle Acellular Infectious Biological Agents - Answer No plasma (cell) membrane No binary fission No way to generate ATP No way to synthesize proteins (no ribosomes) Obligate Intracellular Parasite - Answer Uses host cell for energy and substrates Hijacks host cell's replication machinery Direct the host cell to express viral genes and proteins Nucleocapsid - Answer Unit of viral structure, consists of a capsid with an enclosed nucleus acid Nucleic Acid - Answer Either DNA or RNA Linear or circular segmented Unless or single stranded Capsid - Answer Protein coat around genome Repeating or identical protein subunits (capsomeres) Determines the shape of a virus Naked Viruses - Answer nucleocapsid only, more resistant to disinfectants Enveloped Viruses - Answer have an outer lipid bilayer membrane containing various proteins.

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Microbiology 4000 Chapter 12 –
Viruses Questions and Answers.
Virus - Answer A no cellular particle containing a genome that can replicate only inside a host
cell



Bacteriophage - Answer A virus that infects bacteria



Virion - Answer a complete virus particle



Acellular Infectious Biological Agents - Answer No plasma (cell) membrane

No binary fission

No way to generate ATP

No way to synthesize proteins (no ribosomes)



Obligate Intracellular Parasite - Answer Uses host cell for energy and substrates

Hijacks host cell's replication machinery

Direct the host cell to express viral genes and proteins



Nucleocapsid - Answer Unit of viral structure, consists of a capsid with an enclosed nucleus
acid



Nucleic Acid - Answer Either DNA or RNA

Linear or circular segmented

Unless or single stranded



Capsid - Answer Protein coat around genome

Repeating or identical protein subunits (capsomeres)

Determines the shape of a virus



Naked Viruses - Answer nucleocapsid only, more resistant to disinfectants



Enveloped Viruses - Answer have an outer lipid bilayer membrane containing various
proteins.

, Lipid bilayer - Answer double-layered sheet that forms the core of nearly all cell membranes



matrix/tegument - Answer Protein layer or cluster attaching envelope to nuceloplasmid



Host Range - Answer all the species that can be infected by a given pathogen



Spike proteins - Answer A viral glycoprotein that connects the membrane to the capsid or the
matrix and may be involved in viral binding to host cell receptors



Tail fibers - Answer (complex phages) - attachment



Fiber proteins - Answer Protein attachment On capsid of virus



Icosahedral capsids - Answer Radial symmetry; based on an icosahedron



Helical/ Filamentous capsids - Answer Helical capsid tube around the genome

Generating a flexible filament

Envelope will mask this shape



Complex/ Amorphous - Answer No symmetrical form

Core With flexible core wall

Contains genetic material



Complex Tailed Bacteriophages - Answer Icosahedral head that Contains genetic material and
Tail Injects genetic material into host cells



1. host recognition and attachment.

2. genome entry

3. Biosynthesis

4. assembly (maturation)

5. release - Answer Viral Replication



Plaque - Answer A cell-free zone on a lawn of bacterial cells caused by viral lysis



Temperate Phage - Answer A bacteriophage capable of lysogeny

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