NCLEX-RN® Exam 2026 | 250 Practice Questions &
Detailed Rationales | Comprehensive NCLEX Review
A 43-year-old African American male is admitted with sickle cell anemia. The nurse
plans to assess circulation in the lower extremities every two hours. Which of the fol-
lowing outcome criteria would the nurse use?
Quick Answer: 223
Detailed Answer: 225
1. A 30-year-old male from Haiti is brought to the emergency department in sickle cell
crisis. What is the best position for this client?
, A. Side-lying with knees flexed
B. Knee-chest
C. High Fowler’s with knees flexed
D. Semi-Fowler’s with legs extended on the bed
Quick Answer: 223
Detailed Answer: 225
2. A 25-year-old male is admitted in sickle cell crisis. Which of the following interven-
tions would be of highest priority for this client?
A. Taking hourly blood pressures with mechanical cuff
B. Encouraging fluid intake of at least 200mL per hour
C. Position in high Fowler’s with knee gatch raised
D. Administering Tylenol as ordered
Quick Answer: 223
Detailed Answer: 225
3. Which of the following foods would the nurse encourage the client in sickle cell crisis
to eat?
A. Steak
B. Cottage cheese
C. Popsicle
D. Lima beans
Quick Answer: 223
Detailed Answer: 225
4. A newly admitted client has sickle cell crisis. He is complaining of pain in his feet and
hands. The nurse’s assessment findings include a pulse oximetry of 92. Assuming
that all the following interventions are ordered, which should be done first?
A. Adjust the room temperature
B. Give a bolus of IV fluids
C. Start O2
, D. Administer meperidine (Demerol) 75mg IV push
Quick Answer: 223
Detailed Answer: 225
5. The nurse is instructing a client with iron-deficiency anemia. Which of the following
meal plans would the nurse expect the client to select?
A. Roast beef, gelatin salad, green beans, and peach pie
B. Chicken salad sandwich, coleslaw, French fries, ice cream
C. Egg salad on wheat bread, carrot sticks, lettuce salad, raisin pie
D. Pork chop, creamed potatoes, corn, and coconut cake
Quick Answer: 223
Detailed Answer: 225
6. Clients with sickle cell anemia are taught to avoid activities that cause hypoxia and
hypoxemia. Which of the following activities would the nurse recommend?
A. A family vacation in the Rocky Mountains
B. Chaperoning the local boys club on a snow-skiing trip
C. Traveling by airplane for business trips
D. A bus trip to the Museum of Natural History
Quick Answer: 223
Detailed Answer: 225
7. The nurse is conducting an admission assessment of a client with vitamin B12 defi-
ciency. Which finding reinforces the diagnosis of B12 deficiency?
A. Enlarged spleen
B. Elevated blood pressure
C. Bradycardia
D. Beefy tongue
Quick Answer: 223
Detailed Answer: 225
8. The body part that would most likely display jaundice in the dark-skinned individual is
the:
, A. Conjunctiva of the eye
B. Soles of the feet
C. Roof of the mouth
D. Shins
Quick Answer: 223
Detailed Answer: 225
9. The nurse is conducting a physical assessment on a client with anemia. Which of the
following clinical manifestations would be most indicative of the anemia?
A. BP 146/88
B. Respirations 28 shallow
C. Weight gain of 10 pounds in six months
D. Pink complexion
Quick Answer: 223
Detailed Answer: 226
10. The nurse is teaching the client with polycythemia vera about prevention of compli-
cations of the disease. Which of the following statements by the client indicates a
need for further teaching?
A. “I will drink 500mL of fluid or less each day.”
B. “I will wear support hose.”
C. “I will check my blood pressure regularly.”
D. “I will report ankle edema.”
Quick Answer: 223
Detailed Answer: 226
11. A 33-year-old male is being evaluated for possible acute leukemia. Which of the fol-
lowing findings is most likely related to the diagnosis of leukemia?
A. The client collects stamps as a hobby.
B. The client recently lost his job as a postal worker.
C. The client had radiation for treatment of Hodgkin’s disease as a
teenager.
Detailed Rationales | Comprehensive NCLEX Review
A 43-year-old African American male is admitted with sickle cell anemia. The nurse
plans to assess circulation in the lower extremities every two hours. Which of the fol-
lowing outcome criteria would the nurse use?
Quick Answer: 223
Detailed Answer: 225
1. A 30-year-old male from Haiti is brought to the emergency department in sickle cell
crisis. What is the best position for this client?
, A. Side-lying with knees flexed
B. Knee-chest
C. High Fowler’s with knees flexed
D. Semi-Fowler’s with legs extended on the bed
Quick Answer: 223
Detailed Answer: 225
2. A 25-year-old male is admitted in sickle cell crisis. Which of the following interven-
tions would be of highest priority for this client?
A. Taking hourly blood pressures with mechanical cuff
B. Encouraging fluid intake of at least 200mL per hour
C. Position in high Fowler’s with knee gatch raised
D. Administering Tylenol as ordered
Quick Answer: 223
Detailed Answer: 225
3. Which of the following foods would the nurse encourage the client in sickle cell crisis
to eat?
A. Steak
B. Cottage cheese
C. Popsicle
D. Lima beans
Quick Answer: 223
Detailed Answer: 225
4. A newly admitted client has sickle cell crisis. He is complaining of pain in his feet and
hands. The nurse’s assessment findings include a pulse oximetry of 92. Assuming
that all the following interventions are ordered, which should be done first?
A. Adjust the room temperature
B. Give a bolus of IV fluids
C. Start O2
, D. Administer meperidine (Demerol) 75mg IV push
Quick Answer: 223
Detailed Answer: 225
5. The nurse is instructing a client with iron-deficiency anemia. Which of the following
meal plans would the nurse expect the client to select?
A. Roast beef, gelatin salad, green beans, and peach pie
B. Chicken salad sandwich, coleslaw, French fries, ice cream
C. Egg salad on wheat bread, carrot sticks, lettuce salad, raisin pie
D. Pork chop, creamed potatoes, corn, and coconut cake
Quick Answer: 223
Detailed Answer: 225
6. Clients with sickle cell anemia are taught to avoid activities that cause hypoxia and
hypoxemia. Which of the following activities would the nurse recommend?
A. A family vacation in the Rocky Mountains
B. Chaperoning the local boys club on a snow-skiing trip
C. Traveling by airplane for business trips
D. A bus trip to the Museum of Natural History
Quick Answer: 223
Detailed Answer: 225
7. The nurse is conducting an admission assessment of a client with vitamin B12 defi-
ciency. Which finding reinforces the diagnosis of B12 deficiency?
A. Enlarged spleen
B. Elevated blood pressure
C. Bradycardia
D. Beefy tongue
Quick Answer: 223
Detailed Answer: 225
8. The body part that would most likely display jaundice in the dark-skinned individual is
the:
, A. Conjunctiva of the eye
B. Soles of the feet
C. Roof of the mouth
D. Shins
Quick Answer: 223
Detailed Answer: 225
9. The nurse is conducting a physical assessment on a client with anemia. Which of the
following clinical manifestations would be most indicative of the anemia?
A. BP 146/88
B. Respirations 28 shallow
C. Weight gain of 10 pounds in six months
D. Pink complexion
Quick Answer: 223
Detailed Answer: 226
10. The nurse is teaching the client with polycythemia vera about prevention of compli-
cations of the disease. Which of the following statements by the client indicates a
need for further teaching?
A. “I will drink 500mL of fluid or less each day.”
B. “I will wear support hose.”
C. “I will check my blood pressure regularly.”
D. “I will report ankle edema.”
Quick Answer: 223
Detailed Answer: 226
11. A 33-year-old male is being evaluated for possible acute leukemia. Which of the fol-
lowing findings is most likely related to the diagnosis of leukemia?
A. The client collects stamps as a hobby.
B. The client recently lost his job as a postal worker.
C. The client had radiation for treatment of Hodgkin’s disease as a
teenager.
