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Exam (elaborations)

2026 NP Nursing Practice Mock Exam Q&A with Rationales

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Comprehensive Nurse Practitioner (NP) practice mock exam for 2026 featuring exam-style questions, detailed answer explanations, and rationales. Covers primary care, pharmacology, health assessment, diagnostics, patient management, and clinical decision-making. Ideal for NP students and certification candidates seeking structured revision and exam preparation.

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PNLE/NLE 2026
Nursing Practice III (NP III) - Reviewer Practice Mock Exam

(100 items) ANWERS AT THE END WITH RATIONALE




Based on the PRC PRB-Nursing Enhanced Table of Specifications (TOS) - implemented Nov 2025 and
subsequent schedules (including 2026).


Scope (NP III): Surgery; Oxygenation; Fluids and Electrolytes/Acid-Base/Urinary Elimination;
Infectious, Inflammatory and Immunologic Response; Cellular Aberrations (acute and chronic).


DISCLAIMER
This mock exam and reviewer material is NOT officially endorsed, approved, sponsored, or
affiliated with the Professional Regulation Commission (PRC), the Professional Regulatory
Board of Nursing (PRB-Nursing), or any government agency, professional board, or review
institution.
This material is provided for educational and supplementary review purposes only. Users must
prioritize and rely on their primary review center lectures, official course materials, and standard
nursing references as their main sources of preparation. Users are strongly encouraged to verify
information, consult updated guidelines, and conduct their own research as part of responsible
exam preparation. This mock exam is an original practice resource designed to be aligned with the
PNLE/NLE 2026 Enhanced TOS (NP III) coverage. It does NOT claim to be an exact copy of any
past, present, or future PNLE/NLE questions and does NOT guarantee passing or any specific exam
outcome.
The author/preparer and publisher assume no liability for any loss, damage, or result arising from the
use or misuse of this material, including exam performance. Use of this material constitutes
acceptance of these terms.
Prepared by: Happy Company

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INSTRUCTIONS
1. Choose the one best answer for each item (A, B, C, or D).
2. Answer all questions. There is no penalty for guessing in this mock exam.
3. Rationales and the answer key are provided in the last section. Avoid checking rationales until
you finish the exam.




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,PNLE/NLE 2026 - Nursing Practice III (NP III) Mock Exam (100 items)


Mock Exam Questions (100 items)

1. Pre-operative checklist review: Which finding should the nurse report immediately because it
most directly increases the risk of catastrophic intra-operative bleeding?
A. Recent dose of a direct oral anticoagulant (e.g., rivaroxaban) taken this morning
B. Client has been NPO for 6 hours
C. Baseline blood pressure is 138/84 mmHg
D. Client reports mild anxiety about anesthesia

2. Immediately before signing the operative consent, which action is the nurse's priority?
A. Confirm the surgeon has marked the operative site
B. Verify the client understands the procedure, risks, benefits, and alternatives
C. Administer the ordered pre-op antibiotic
D. Start the maintenance IV fluid

3. In the operating room, which event best reflects adherence to the Universal Protocol?
A. Anesthesia provider confirms allergies in pre-op holding
B. Scrub nurse counts sponges after skin closure
C. Team performs a time-out confirming patient identity, procedure, and site immediately before
incision
D. Circulating nurse documents vital signs every 5 minutes

4. A client with a history of malignant hyperthermia is scheduled for surgery. Which preparation is
most appropriate?
A. Place the client on a warming blanket pre-operatively
B. Administer a benzodiazepine as the primary prophylaxis
C. Use nitrous oxide as the anesthetic of choice
D. Ensure dantrolene is immediately available and anesthesia machine is prepared to avoid
triggering agents
5. During induction of anesthesia, the client's jaw is clenched and there is sudden rise in end-tidal
CO2 and heart rate. Which action should the nurse anticipate first?
A. Stop triggering anesthetic agents and administer dantrolene per protocol
B. Increase IV fluids and observe for improvement
C. Apply ice packs to the axillae and groin only
D. Administer naloxone

6. A client returns from PACU after abdominal surgery. Which assessment finding requires the
most urgent intervention?
A. Pain rating 8/10 at incision site
B. Stridor with use of accessory muscles
C. Temperature 37.8 C
D. Urine output 40 mL in the last hour

7. Post-operative teaching after general anesthesia: Which instruction best reduces risk of atelectasis?
A. Restrict oral fluids for 24 hours
B. Remain on bed rest for 48 hours
C. Use incentive spirometry 10 times each hour while awake
D. Keep the head of bed flat

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, PNLE/NLE 2026 - Nursing Practice III (NP III) Mock Exam (100 items)




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