MN 551 MIDTERM EXAM (PURDUE) NEWEST 2026
ACTUAL EXAM TEST BANK| MN551 PATHO MIDTERM
REVIEW WITH COMPLETE REAL EXAM QUESTIONS AND
CORRECT VERIFIED ANSWERS/ ALREADY GRADED A+
1. Which medication is a first-line agent for treating hypertension in a
patient with diabetes and proteinuria?
A. Hydrochlorothiazide
B. Lisinopril
C. Propranolol
D. Amlodipine
Answer: B
Rationale: ACE inhibitors (like lisinopril) reduce proteinuria and protect
kidney function in diabetic nephropathy.
2. Which antibiotic is associated with increased risk of tendon rupture,
especially in older adults?
A. Cephalexin
B. Doxycycline
C. Ciprofloxacin
D. Amoxicillin
Answer: C
pg. 1
,Rationale: Fluoroquinolones (like ciprofloxacin) can cause tendonitis
and tendon rupture.
3. What is the primary mechanism of action of metformin?
A. Increases insulin secretion
B. Decreases hepatic glucose production
C. Increases renal glucose reabsorption
D. Stimulates glucagon release
Answer: B
Rationale: Metformin primarily reduces hepatic glucose output.
4. Which antihypertensive is contraindicated in pregnancy?
A. Methyldopa
B. Hydralazine
C. Lisinopril
D. Nifedipine
Answer: C
Rationale: ACE inhibitors are teratogenic and contraindicated in
pregnancy.
5. Which statin is least likely to interact with CYP3A4 inhibitors?
A. Atorvastatin
B. Simvastatin
pg. 2
,C. Pravastatin
D. Lovastatin
Answer: C
Rationale: Pravastatin is not significantly metabolized by CYP3A4.
6. Which medication is a preferred initial therapy for heart failure with
reduced ejection fraction?
A. Verapamil
B. Metoprolol succinate
C. Diltiazem
D. Nifedipine
Answer: B
Rationale: Select beta-blockers (like metoprolol succinate) improve
mortality in HFrEF.
7. What is a common side effect of amiodarone?
A. Hypokalemia
B. Pulmonary fibrosis
C. Gingival hyperplasia
D. Hearing loss
Answer: B
Rationale: Amiodarone can cause serious pulmonary toxicity.
pg. 3
, 8. Which drug is indicated as an antidote for acetaminophen overdose?
A. Flumazenil
B. N-acetylcysteine
C. Atropine
D. Naloxone
Answer: B
Rationale: N-acetylcysteine replenishes glutathione in acetaminophen
toxicity.
9. Which insulin has the fastest onset of action?
A. Regular insulin
B. NPH insulin
C. Insulin glargine
D. Insulin lispro
Answer: D
Rationale: Lispro is a rapid-acting insulin analogue.
10. Which medication is most appropriate for acute angina relief?
A. Metoprolol
B. Nitroglycerin
C. Ranolazine
D. Amlodipine
pg. 4
ACTUAL EXAM TEST BANK| MN551 PATHO MIDTERM
REVIEW WITH COMPLETE REAL EXAM QUESTIONS AND
CORRECT VERIFIED ANSWERS/ ALREADY GRADED A+
1. Which medication is a first-line agent for treating hypertension in a
patient with diabetes and proteinuria?
A. Hydrochlorothiazide
B. Lisinopril
C. Propranolol
D. Amlodipine
Answer: B
Rationale: ACE inhibitors (like lisinopril) reduce proteinuria and protect
kidney function in diabetic nephropathy.
2. Which antibiotic is associated with increased risk of tendon rupture,
especially in older adults?
A. Cephalexin
B. Doxycycline
C. Ciprofloxacin
D. Amoxicillin
Answer: C
pg. 1
,Rationale: Fluoroquinolones (like ciprofloxacin) can cause tendonitis
and tendon rupture.
3. What is the primary mechanism of action of metformin?
A. Increases insulin secretion
B. Decreases hepatic glucose production
C. Increases renal glucose reabsorption
D. Stimulates glucagon release
Answer: B
Rationale: Metformin primarily reduces hepatic glucose output.
4. Which antihypertensive is contraindicated in pregnancy?
A. Methyldopa
B. Hydralazine
C. Lisinopril
D. Nifedipine
Answer: C
Rationale: ACE inhibitors are teratogenic and contraindicated in
pregnancy.
5. Which statin is least likely to interact with CYP3A4 inhibitors?
A. Atorvastatin
B. Simvastatin
pg. 2
,C. Pravastatin
D. Lovastatin
Answer: C
Rationale: Pravastatin is not significantly metabolized by CYP3A4.
6. Which medication is a preferred initial therapy for heart failure with
reduced ejection fraction?
A. Verapamil
B. Metoprolol succinate
C. Diltiazem
D. Nifedipine
Answer: B
Rationale: Select beta-blockers (like metoprolol succinate) improve
mortality in HFrEF.
7. What is a common side effect of amiodarone?
A. Hypokalemia
B. Pulmonary fibrosis
C. Gingival hyperplasia
D. Hearing loss
Answer: B
Rationale: Amiodarone can cause serious pulmonary toxicity.
pg. 3
, 8. Which drug is indicated as an antidote for acetaminophen overdose?
A. Flumazenil
B. N-acetylcysteine
C. Atropine
D. Naloxone
Answer: B
Rationale: N-acetylcysteine replenishes glutathione in acetaminophen
toxicity.
9. Which insulin has the fastest onset of action?
A. Regular insulin
B. NPH insulin
C. Insulin glargine
D. Insulin lispro
Answer: D
Rationale: Lispro is a rapid-acting insulin analogue.
10. Which medication is most appropriate for acute angina relief?
A. Metoprolol
B. Nitroglycerin
C. Ranolazine
D. Amlodipine
pg. 4
