MULTIPLE SCLEROSIS CERTIFIED
SPECIALIST ACTUAL SCRIPT 2026 FULL
QUESTIONS AND SOLUTIONS
●● What characterizes Multiple Sclerosis? Answer: Disseminated
demyelination of nerve fibers in the brain and spinal cord.
●● What is the typical age of onset for Multiple Sclerosis? Answer:
Usually between ages 20 and 40.
●● Which gender is more affected by Multiple Sclerosis? Answer:
Women, who are affected 2 to 3 times more often than men.
●● What is the primary problem in Multiple Sclerosis? Answer: An
autoimmune process driven by activated T cells.
●● What are the three marked processes in Multiple Sclerosis? Answer:
Chronic inflammation, demyelination, and gliosis.
●● What symptom may be the first sign of Multiple Sclerosis? Answer:
Vision changes.
, ●● What is Lhermitte's sign? Answer: A temporary sensory symptom
described as an electric shock sensation down the spine or into limbs
with neck flexion.
●● What are common bowel issues in Multiple Sclerosis? Answer:
Usually involves constipation.
●● What types of bladder problems can occur in Multiple Sclerosis?
Answer: Spastic bladder and flaccid bladder.
●● What cognitive issues are associated with Multiple Sclerosis?
Answer: Problems with multitasking, concentration, short-term memory,
speed of processing, and word finding.
●● What are the four primary patterns of clinical course in Multiple
Sclerosis? Answer: Relapsing-remitting, primary-progressive,
secondary-progressive, and progressive-relapsing.
●● What diagnostic studies are used for Multiple Sclerosis? Answer:
MRI with contrast and CSF analysis.
●● What must be present for a diagnosis of Multiple Sclerosis? Answer:
Evidence of at least 2 inflammatory demyelinating lesions in at least 2
different locations in the CNS and two or more attacks occurring at
different times.
SPECIALIST ACTUAL SCRIPT 2026 FULL
QUESTIONS AND SOLUTIONS
●● What characterizes Multiple Sclerosis? Answer: Disseminated
demyelination of nerve fibers in the brain and spinal cord.
●● What is the typical age of onset for Multiple Sclerosis? Answer:
Usually between ages 20 and 40.
●● Which gender is more affected by Multiple Sclerosis? Answer:
Women, who are affected 2 to 3 times more often than men.
●● What is the primary problem in Multiple Sclerosis? Answer: An
autoimmune process driven by activated T cells.
●● What are the three marked processes in Multiple Sclerosis? Answer:
Chronic inflammation, demyelination, and gliosis.
●● What symptom may be the first sign of Multiple Sclerosis? Answer:
Vision changes.
, ●● What is Lhermitte's sign? Answer: A temporary sensory symptom
described as an electric shock sensation down the spine or into limbs
with neck flexion.
●● What are common bowel issues in Multiple Sclerosis? Answer:
Usually involves constipation.
●● What types of bladder problems can occur in Multiple Sclerosis?
Answer: Spastic bladder and flaccid bladder.
●● What cognitive issues are associated with Multiple Sclerosis?
Answer: Problems with multitasking, concentration, short-term memory,
speed of processing, and word finding.
●● What are the four primary patterns of clinical course in Multiple
Sclerosis? Answer: Relapsing-remitting, primary-progressive,
secondary-progressive, and progressive-relapsing.
●● What diagnostic studies are used for Multiple Sclerosis? Answer:
MRI with contrast and CSF analysis.
●● What must be present for a diagnosis of Multiple Sclerosis? Answer:
Evidence of at least 2 inflammatory demyelinating lesions in at least 2
different locations in the CNS and two or more attacks occurring at
different times.
