D116 Pharmacology Study
Guide
Pharmacology (Western
Governors University)
,Grapefruit juice inhibits CYP3A4, which lowers the
metabolism of some drugs, leading to toxic effects of drugs
affected by these isoenzymes.
Some foods can inhibit CYP isoenzymes and alter drug metabolism.
With respect to the cytochrome P450 (CYP) system, what will
result in a higher concentration of a drug? Inhibition of the
enzyme (Decreasing
, enzyme activity leads to decreased metabolism of the drug.)
The therapeutic index is calculated by dividing the median
toxic dose by the median efficacious dose.
antibiotics can interact with warfarin and his PT/INR needs to
be checked more often.
Morphine is a medication that is selective to receptor types
that regulate more than one process. Hence –Constipation
Schedule IV substance and all scheduled substances require
the prescriber to be registered with the DEA.
A special waiver (DATA 2000) is required in addition to your
DEA registration in order to prescribe Schedule II and
Schedule III controlled substances for addiction.
Macrolide antibiotics are inhibitors of the cytochrome system.
Therapeutic drug monitoring promotes an individualized drug
plan based on serum levels of drug and patient outcomes.
Digoxin is a narrow therapeutic window index drug that
requires levels to be drawn frequently to assess for efficacy
and toxicity.
Guide
Pharmacology (Western
Governors University)
,Grapefruit juice inhibits CYP3A4, which lowers the
metabolism of some drugs, leading to toxic effects of drugs
affected by these isoenzymes.
Some foods can inhibit CYP isoenzymes and alter drug metabolism.
With respect to the cytochrome P450 (CYP) system, what will
result in a higher concentration of a drug? Inhibition of the
enzyme (Decreasing
, enzyme activity leads to decreased metabolism of the drug.)
The therapeutic index is calculated by dividing the median
toxic dose by the median efficacious dose.
antibiotics can interact with warfarin and his PT/INR needs to
be checked more often.
Morphine is a medication that is selective to receptor types
that regulate more than one process. Hence –Constipation
Schedule IV substance and all scheduled substances require
the prescriber to be registered with the DEA.
A special waiver (DATA 2000) is required in addition to your
DEA registration in order to prescribe Schedule II and
Schedule III controlled substances for addiction.
Macrolide antibiotics are inhibitors of the cytochrome system.
Therapeutic drug monitoring promotes an individualized drug
plan based on serum levels of drug and patient outcomes.
Digoxin is a narrow therapeutic window index drug that
requires levels to be drawn frequently to assess for efficacy
and toxicity.
