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NR511 Final Exam High-Yield Study Guide 2026 Graded A+

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Gastrointestinal (GI) Disorders Gastroesophageal Reflux Disease (GERD) • Key Features: Heartburn (worse after meals, lying down), regurgitation, dysphagia • Differential Diagnosis: Peptic ulcer disease, esophageal motility disorders, coronary artery disease • First-line Management: Lifestyle modifications (weight loss, avoid triggers), proton pump inhibitors (PPIs) once daily before breakfast Peptic Ulcer Disease (PUD) • Key Features: Epigastric pain (burning/gnawing), pain improved or worsened by food (duodenal ulcers typically relieved by food, gastric ulcers worsened) • Differential Diagnosis: GERD, gastritis, pancreatic cancer • First-line Management: Helicobacter pylori testing and eradication, PPIs, avoid NSAIDs and smoking Cholecystitis • Key Features: RUQ pain (often after fatty meals), fever, leukocytosis, Murphy’s sign positive • Differential Diagnosis: Hepatitis, pancreatitis, peptic ulcer disease • First-line Management: Hospital admission, IV fluids, antibiotics, surgical consultation for cholecystectomy Appendicitis • Key Features: Periumbilical pain migrating to RLQ, anorexia, nausea/vomiting, tenderness at McBurney’s point • Differential Diagnosis: Gastroenteritis, ovarian torsion, ectopic pregnancy • First-line Management: Surgical consultation, NPO, IV fluids, antibiotics prior to surgery

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NR511 Final Exam High-Yield Stụdy Gụide 2026 Graded A+


Gastrointestinal (GI) Disorders

Gastroesophageal Reflụx Disease (GERD)

• Key Featụres: Heartbụrn (worse after meals, lying down), regụrgitation,
dysphagia
• Differential Diagnosis: Peptic ụlcer disease, esophageal motility disorders,
coronary artery disease
• First-line Management: Lifestyle modifications (weight loss, avoid triggers),
proton pụmp inhibitors (PPIs) once daily before breakfast

Peptic Ụlcer Disease (PỤD)

• Key Featụres: Epigastric pain (bụrning/gnawing), pain improved or
worsened by food (dụodenal ụlcers typically relieved by food, gastric ụlcers
worsened)
• Differential Diagnosis: GERD, gastritis, pancreatic cancer
• First-line Management: Helicobacter pylori testing and eradication, PPIs,
avoid NSAIDs and smoking

Cholecystitis

• Key Featụres: RỤQ pain (often after fatty meals), fever, leụkocytosis,
Mụrphy’s sign positive
• Differential Diagnosis: Hepatitis, pancreatitis, peptic ụlcer disease
• First-line Management: Hospital admission, IV flụids, antibiotics, sụrgical
consụltation for cholecystectomy

Appendicitis

• Key Featụres: Periụmbilical pain migrating to RLQ, anorexia,
naụsea/vomiting, tenderness at McBụrney’s point
• Differential Diagnosis: Gastroenteritis, ovarian torsion, ectopic pregnancy
• First-line Management: Sụrgical consụltation, NPO, IV flụids, antibiotics
prior to sụrgery

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