Exam Questions and Correct
Answers | New Update
What is the first line of tx for anxiety disorder? - ANSWER ✔✔SSRI
for chronic anxiety, GAD, panic disorder
Between TCA vs. SSRI vs Benzo, which has the highest anticholinergic
effects? - ANSWER ✔✔TCA
Activating antidepressants that can result in symptoms of anxiety,
agitation, restlessness? - ANSWER ✔✔venlafaxine
,What medical conditions may precipitate anxiety? - ANSWER
✔✔Endocrine: DM, thyroid
Neuro: seizures
Resp: COPD/ asthma
Cardiac disease
MOA of benzodiazepines: - ANSWER ✔✔-enhance activity of GABA
at GABA-A receptor
-enhancing the effects of Gamma-aminobutyric acid GABA
-work as positive allosteric modulators, bind to specific receptor site and
increase receptor's affinity for GABA
--> increased chloride ion influx neurons leading to hyperpolarization and
decreased neuronal excitability
What are the effects of benzos in the elderly population? - ANSWER
✔✔-increased fall risk
-hip fx risk
, Clinical concerns when prescribing benzodiazepines: - ANSWER
✔✔-potential for abuse & addiction
-pt becomes physical dependence and builds tolerance
-known limitations of benzo= rebound insomnia
Benzodiazepines recommended for patients w/ liver disorders, alcohol
use disorders: - ANSWER ✔✔OTL= lorazepam, oxazpam,
temazepam= not metabolized by liver
When can benzodiazepines can be administered in anxiety patients? -
ANSWER ✔✔-panic attacks
-useful in the initial weeks of SSRI/ SNRI initiation to rapidly reduce
anxiety
CM of benzo withdrawal: - ANSWER ✔✔-similar to ETOH withdrawal
-insomnia
-anxiety
-hand tremors
-irritability
-anorexia
-n/v
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