PCB 4233 Quiz 1-12/ Exam MC Complete
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(Graded A+) | Brand New 2026/27
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Terms in this set (168)
,8. Yersinia pestis, the causative B. Increased production of TNF-a and IL-6
agent of the bubonic plague, has
multiple mechanisms of immune
evasion. This Gram-negative
bacterium is transmitted from fleas
(body temperature 26 deg C) to
humans (body temperature 37 deg
C) by flea bites. Studies have shown
that the lipopolysaccharide (LPS)
produced by Y. pestis grown at 37
deg C is about 10-fold less potent
at stimulating TLR4 signaling than is
the Y. pestis LPS from bacteria
grown at 26 deg C. When these two
forms of Y. pestis LPS are compared
for their abilities to induce
responses from human
macrophages, one would expect
that the 26 deg C Y. pestis LPS
would result in:
A. Increased production of
antimicrobial peptides
B. Increased production of TNF-a
and IL-6
C. Reduced production of IL-10
D. Increased activation of the
inflammasome
E.Reduced production of Type 1
interferons
,1. An infant with recurrent bacterial D. The defective immune response occurs too
and fungal infections is suspected rapidly following infection to be due to a defect
to have an in B or T lymphocytes responses.
immunodeficiency disease. Within
two days after exposure to a
pathogen, the organisms have
proliferated to dangerous levels
requiring immediate systemic
antibiotic treatment. It is
unlikely that this infant has a defect
in B or T lymphocyte responses to
the infection because:
A. Systemic infections of bacteria
and fungi are usually cleared by the
spleen.
B. Bacteria and fungi do not require
B cell or T cell responses for their
clearance.
C. Bacteria and fungi are not
efficiently transported to draining
lymph nodes to initiate adaptive
immune responses.
D. The defective immune response
occurs too rapidly following
infection to be due to a defect
in B or T lymphocytes responses.
E. Adaptive immune responses
require dendritic cells to take up
and degrade pathogens.
, 2. In patients with lymphomas, the B. Endothelial cells
cancer cells invade the bone
marrow and destroy the
environment required for normal
hematopoiesis. This leads to bone
marrow failure, which
disrupts the production of
hematopoietic cell lineages. All of
the following cell types would be
affected by this EXCEPT:
A. Red blood cells
B. Endothelial cells
C. Lymphocytes
D. Dendritic cells
E. Neutrophils
Questions and Answers with Verified Solutions
(Graded A+) | Brand New 2026/27
Save
Terms in this set (168)
,8. Yersinia pestis, the causative B. Increased production of TNF-a and IL-6
agent of the bubonic plague, has
multiple mechanisms of immune
evasion. This Gram-negative
bacterium is transmitted from fleas
(body temperature 26 deg C) to
humans (body temperature 37 deg
C) by flea bites. Studies have shown
that the lipopolysaccharide (LPS)
produced by Y. pestis grown at 37
deg C is about 10-fold less potent
at stimulating TLR4 signaling than is
the Y. pestis LPS from bacteria
grown at 26 deg C. When these two
forms of Y. pestis LPS are compared
for their abilities to induce
responses from human
macrophages, one would expect
that the 26 deg C Y. pestis LPS
would result in:
A. Increased production of
antimicrobial peptides
B. Increased production of TNF-a
and IL-6
C. Reduced production of IL-10
D. Increased activation of the
inflammasome
E.Reduced production of Type 1
interferons
,1. An infant with recurrent bacterial D. The defective immune response occurs too
and fungal infections is suspected rapidly following infection to be due to a defect
to have an in B or T lymphocytes responses.
immunodeficiency disease. Within
two days after exposure to a
pathogen, the organisms have
proliferated to dangerous levels
requiring immediate systemic
antibiotic treatment. It is
unlikely that this infant has a defect
in B or T lymphocyte responses to
the infection because:
A. Systemic infections of bacteria
and fungi are usually cleared by the
spleen.
B. Bacteria and fungi do not require
B cell or T cell responses for their
clearance.
C. Bacteria and fungi are not
efficiently transported to draining
lymph nodes to initiate adaptive
immune responses.
D. The defective immune response
occurs too rapidly following
infection to be due to a defect
in B or T lymphocytes responses.
E. Adaptive immune responses
require dendritic cells to take up
and degrade pathogens.
, 2. In patients with lymphomas, the B. Endothelial cells
cancer cells invade the bone
marrow and destroy the
environment required for normal
hematopoiesis. This leads to bone
marrow failure, which
disrupts the production of
hematopoietic cell lineages. All of
the following cell types would be
affected by this EXCEPT:
A. Red blood cells
B. Endothelial cells
C. Lymphocytes
D. Dendritic cells
E. Neutrophils
