(LAT) Questions and Answers Exam
Erasistratus - ANSWER>>Early philosopher that studied animal anatomy and was
the first to demonstrate that the heart's valves limit blood flow to one direction
Early 1500's - ANSWER>>The time period signifying the start of the modern
experimental era
William Harvey - ANSWER>>English physician and scientist who described the
circulation of the blood in the 1600s
Carl Linnaeus - ANSWER>>Physician and zoologist who developed a taxonomic
system that classified organisms based on anatomical traits
Claude Bernard - ANSWER>>Validated the scientific method in France (1800s)
Louis Pasteur - ANSWER>>A French chemist, this man discovered that heat could
kill bacteria that otherwise spoiled liquids. Studied infectious disease.
Robert Koch - ANSWER>>Developed the culture plate method to identify
pathogens
Dr. Walter Reed - ANSWER>>Confirmed that yellow fever was transmitted via
mosquito species in the early 1900s
Compound microscope - ANSWER>>Invented in the late 1500s, aided in research
development
,Research study - ANSWER>>Systematic investigation to establish facts; Define
question --> formulate objective framework --> establish hypothesis --> create
research design --> identify variables --> collect/analyze data --> report data and
conclusions
Grants - ANSWER>>Provide money for 3 to 5-year period during which the
investigator must conduct the study and publish results in one or more scientific
journals
NIH - ANSWER>>Most ______ grants go to research programs at colleges and
universities
NIH & NSF - ANSWER>>what are the 2 main public agencies that fund research
NSF - ANSWER>>Agency supporting non-biomedical research that may involved
animals (physics, chemistry, engineering, etc.)
Office of Research and Grants - ANSWER>>Administrative unit that manages
grants, supports, research activities, assists grantees in managing their grants,
helps search for grant opportunities, and protects intellectual property rights
OLAW (Office of Laboratory Animal Welfare) - ANSWER>>monitors compliance
with PHS policy by assured institutions through site visits
IACUC - ANSWER>>Mandated by federal law and institutional policies that govern
the use of animals in research
CEO - ANSWER>>Appoints members of the IACUC
USDA, OLAW, and AAALAC - ANSWER>>The IACUC can suspend animal-related
activities at any time, but they must notify _________
,5 consecutive hours - ANSWER>>the twenty-eight hour law dictates that animals
cannot be transported for >28 hours without being unloaded for at least _______
for rest, water, and food
Cruelty to Animals Act (Britain 1876) - ANSWER>>first law limiting animal
experimentation
AWR (Animal Welfare Regulations) - ANSWER>>mandate that protocols for USDA-
covered species may only be approved for 1 year
Laboratory Animal Welfare Act of 1966 - ANSWER>>first law in U.S. addressing
animal use in research; established care and use standards for animals including
housing, sale, transport, dealer licensing, facility registration, and identification of
dogs and cats
USDA - ANSWER>>tasked with enforcing the laboratory animal welfare act of
1966
Animal Welfare Act (AWA) - ANSWER>>the laboratory animal welfare act of 1966
was renamed to this in 1970 to cover all warm-blooded animals used in research,
sold as pets, or used in exhibitions; required all animal dealers to be licensed and
mandated use of pain-relieving drugs for animals used in regulated activities
1985 amendment to the animal welfare act (AWA) - ANSWER>>called for
excersize for dogs and psychological enrichment for primates, minimizing
pain/distress and only 1 major surgery/animal with exceptions
National Agricultural Library (NAL) - ANSWER>>assists researchers in preventing
unnecessary duplication, reducing pain and distress (resulted from 1985
amendment to AWA)
, live or dead dog, cat, primate guinea pig, hamster, rabbit, or other warm-blooded
animals used for research/pets; excludes birds, rats, mice, farm animals, and
horses (not used for research) - ANSWER>>AWA definition for 'animal'
Animal Welfare Regulations - ANSWER>>developed by the USDA to enforce the
AWA; establishes rules and standards for humane care and treatment of covered
species
Terms, Regulations, Standards, Rules of Practice - ANSWER>>Four parts of the
animal welfare regulations (AWR) developed by the USDA to enforce the AWA
Animal and Plant Health Inspection Service (APHIS) - ANSWER>>administers AWR
(animal welfare regulations) to enforce the AWA (animal welfare act)
USDA veterinary medical officers (VMO) - ANSWER>>conduct unannounced
inspections of animal care and use programs following the Animal Care Inspection
Guide in order to enforce the AWA through APHIS
APHIS - ANSWER>>Animal and Plant Health Inspection Service
IO - ANSWER>>person responsible for making sure the organization is AWA-
compliant
USDA - ANSWER>>research facilities must register with ______ if they use AWA-
covered species, registration must be signed by IO/CEO
Annually - ANSWER>>Institutions housing USDA-covered animals must submit a
report to the USDA including location of animal facilities, how many animals used,
and pain categories HOW OFTEN?
Animal facility - ANSWER>>building, room, area, enclosure, or vehicle used for
animal confinement, transport, maintenance, breeding, or experiments (includes