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Moleculaire Biologie

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Moleculaire Biologie
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Moleculaire Biologie
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Moleculaire Biologie Coderende streng Heeft dezelfde sequentie als mRNA (T→U). Waar bindt RNA‑polymerase? Aan de promoter (TATA‑box). TFIIH functie Opent DNA en fosforyleert polymerase. 5'-capping 7‑methyl‑G toevoegen voor bescherming en herkenning. Splicing Introns eruit, exons aan elkaar. Poly‑A‑tail ±200 A's → stabiliteit, export, translatie. mRNA‑export Alleen met cap, poly‑A en EJC's via nuclear pore. Translatie Ribosomen maken eiwitten op basis van mRNA. Startcodon AUG (methionine). Stopcodons UAA, UAG, UGA. tRNA functie Brengt aminozuren; anticodon herkent codon.

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