NURS 611 Advanced Pathophysiology Exam 2
Questions and Answers | Latest Update 2026
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Terms in this set (116)
SIADH (syndrome of inappropriate *Over secretion of ADH, Kidneys retain water
antidiuretic hormone) causing hypervolemia (dilute sodium-
Causes hyponatremia)
S/S
Treatment CAUSES- cancers, lung cancer, duodenum, etc
Infection in lungs or CNS -> pneumonia,
meningitis,
AVP gene mutation, any surgerys
medication- Chlopropamide (oral antidiabetic)
S/S- THIRSTY, DEC urine (very concentrated) ,
anoerxia, (not hungry/uncomfortable) fluid
overload, dyspnea fatigue vomiting,
hyponatremia, confusion, seizures
Treatment - Treat hyponatremia
,Diabetes Insuipidus (DI) *DECREASED secretion of ADH,
Patho diluted and excessive urine output,
Causes (concentrated -> Hypernatremia, INC plasma
S/S osmalality),
Treatment
CAUSES- ** Nephrogenic - problems with the
kidneys- Genetic (Vasopressin & Aquaphorin
genes),
diseases- amyloidosis & pylenephritis
Drug- lithium carbonate (can damage kidney
tubules)
** Neurogenic - lesions or trauma to
hypothalamus, posterior pituitary, TBI
complications
Pregnancy- body produces vasopressinase which
causes ADH to break down (decrease)
S/S- polydispisa (extreme thirst), Inc Urine output
(Polyuria) diluted, hypotension,
Treatment- If tolerable, Drink alot of water to
correct the problem
Antidiuretic Hormone Produced by the hypothalamus
Where is it produced? secreted and stored by the posterior pituitary
Where is it stored/secreted? regulates the amount of water in the body
Normal function (can also constrict blood vessels and also called
vasopressin)
, Hypopituitarism (Disease of the anterior pituitary)
Cause- ischemia/infarction, edema, adenoma,
aneyursm of the pituitary - pituitary enlarges due
to edema which causes more damage (pituitary is
in an enclosed space) -> Tiusse damage,
decreased blood supply, fibrosis
Dec in all pituitary hormones-
(Panhypopituitarism)
ACTH - Adrenocorticotropic
TSH- thyroid stimulating hormone
FSH & LH follicle stimulating & Lutenizing
GH- Growth hormone
Oxytocin Toxicity / Oxytocin Disease of posterior pituitary
Insufficiency Hyper secretion- Toxicity
Hypo secretion- Insufficiency
ACTH Deficiency (Hypopituitarism) N/V, weakness, lack of energy
Adrenocorticotropic deficiency HYPOGLYCEMIA, hypocortisol, low urine
due to hypocortisol insulin sensitivity is increased
due to less glycogen stores/ less glucogensis
Can be life threatening
Low aldosterone (RAAS can help)
Low urine output
TSH Deficiency (hypopituitarism) Same as hypothyroidism
Thyroid Stimulating Hormone Cold intolerance, Myxedema (wax appearance of
Deficiency swelled skin), Slowed metabolic rate (inc weight
gain?),
contipation, dry skin, fatigue
Questions and Answers | Latest Update 2026
Save
Terms in this set (116)
SIADH (syndrome of inappropriate *Over secretion of ADH, Kidneys retain water
antidiuretic hormone) causing hypervolemia (dilute sodium-
Causes hyponatremia)
S/S
Treatment CAUSES- cancers, lung cancer, duodenum, etc
Infection in lungs or CNS -> pneumonia,
meningitis,
AVP gene mutation, any surgerys
medication- Chlopropamide (oral antidiabetic)
S/S- THIRSTY, DEC urine (very concentrated) ,
anoerxia, (not hungry/uncomfortable) fluid
overload, dyspnea fatigue vomiting,
hyponatremia, confusion, seizures
Treatment - Treat hyponatremia
,Diabetes Insuipidus (DI) *DECREASED secretion of ADH,
Patho diluted and excessive urine output,
Causes (concentrated -> Hypernatremia, INC plasma
S/S osmalality),
Treatment
CAUSES- ** Nephrogenic - problems with the
kidneys- Genetic (Vasopressin & Aquaphorin
genes),
diseases- amyloidosis & pylenephritis
Drug- lithium carbonate (can damage kidney
tubules)
** Neurogenic - lesions or trauma to
hypothalamus, posterior pituitary, TBI
complications
Pregnancy- body produces vasopressinase which
causes ADH to break down (decrease)
S/S- polydispisa (extreme thirst), Inc Urine output
(Polyuria) diluted, hypotension,
Treatment- If tolerable, Drink alot of water to
correct the problem
Antidiuretic Hormone Produced by the hypothalamus
Where is it produced? secreted and stored by the posterior pituitary
Where is it stored/secreted? regulates the amount of water in the body
Normal function (can also constrict blood vessels and also called
vasopressin)
, Hypopituitarism (Disease of the anterior pituitary)
Cause- ischemia/infarction, edema, adenoma,
aneyursm of the pituitary - pituitary enlarges due
to edema which causes more damage (pituitary is
in an enclosed space) -> Tiusse damage,
decreased blood supply, fibrosis
Dec in all pituitary hormones-
(Panhypopituitarism)
ACTH - Adrenocorticotropic
TSH- thyroid stimulating hormone
FSH & LH follicle stimulating & Lutenizing
GH- Growth hormone
Oxytocin Toxicity / Oxytocin Disease of posterior pituitary
Insufficiency Hyper secretion- Toxicity
Hypo secretion- Insufficiency
ACTH Deficiency (Hypopituitarism) N/V, weakness, lack of energy
Adrenocorticotropic deficiency HYPOGLYCEMIA, hypocortisol, low urine
due to hypocortisol insulin sensitivity is increased
due to less glycogen stores/ less glucogensis
Can be life threatening
Low aldosterone (RAAS can help)
Low urine output
TSH Deficiency (hypopituitarism) Same as hypothyroidism
Thyroid Stimulating Hormone Cold intolerance, Myxedema (wax appearance of
Deficiency swelled skin), Slowed metabolic rate (inc weight
gain?),
contipation, dry skin, fatigue
