MIC 130 LATEST EXAMS SCRIPT ALL QUESTIONS
AND ANSWERS SURE A+
✔✔Category B agents - ✔✔Moderately easy to disseminate. Moderate morbidity and
low mortality
Ex: Typhus, Glanders
✔✔Category C agents - ✔✔Include emerging pathogens that could be engineered that
are easily available. Potential is there for high morbidity and mortality
Ex: Yellow fever virus, Dengue fever virus, MDR-Tb
✔✔Zoonotic disease - ✔✔diseases of animals that can be transmitted to humans
✔✔vector transmitted zoonotic disease - ✔✔diseases that are transmitted to humans by
an animal
✔✔emerging infections - ✔✔infectious diseases whose incidence in humans has
increased recently
✔✔Re-emerging diseases - ✔✔infectious diseases that were under control and are now
on the rise
✔✔Zika Emergence - ✔✔-First seen in Uganda in 1947 in a monkey
, -Transmitted by mosquito bite
-No treatment or vaccine is available
-Symptoms: fever, rash, joint pain, conjunctivitis
✔✔How do human activities increase emergence of disease? - ✔✔Global air travel;
moving great distances in short periods of time, moving microbes easily
✔✔Zika emergence in the US (2015) - ✔✔-5,754 cases reported
-Most were travel-associated
-229 local mosquito-borne (FL, TX)
-55 other case (52 sex, 2 lab, 1 unknown)
✔✔Lyme disease - ✔✔-Emerged in 1982
-From contact with wild or exotic animal species
-increased deer populations, deer mouse, and tick populaitons in proximity to human
habitation
✔✔Zoonoses - ✔✔Diseases of animals (reservior hosts) that may be transmitted ot
humans under natural conditions
Many have a vector (insects, ticks or mites)
Ex: Rabies, lyme disease, plague, West nile, Monkey pox
✔✔Monkey pox - ✔✔-Discoverd in 1958 in monkey colony
-First human case 1970 in DRC
-Human to human transmission from direct contact, respiratory tract or mucous
membranes (eye, nose, mouth)
-Similar to small pox but milder: fever, headaches, muscle aches, exhaustion, swollen
nodes, rash 1-3 days later
-Small pox vaccine offers some protection
✔✔Monkey pox virus in US - ✔✔-2003 outbreak in Marshfield Wisconsin
-Imported Gambian giant rats, prarie dogs as pets
-Pet dealer in texas brought infected rats
-Companies in texas suck up prarie dogs because they are a nucence to farming
-Rats and dogs had enough contact to be infected
-Prarie dogs bit and scratched infecting humans
-Banned imported rats to prevent disease spread
✔✔Challenges with Zika - ✔✔Can't tell who has it. Mosquito control, Population of
children with macrocephaly. Lack of access to birth control. How to distribute birth
control
✔✔Hantavirus Pulmonary Syndrome - ✔✔Outbreak in May 1993 in the four corner
region of the southwest US
AND ANSWERS SURE A+
✔✔Category B agents - ✔✔Moderately easy to disseminate. Moderate morbidity and
low mortality
Ex: Typhus, Glanders
✔✔Category C agents - ✔✔Include emerging pathogens that could be engineered that
are easily available. Potential is there for high morbidity and mortality
Ex: Yellow fever virus, Dengue fever virus, MDR-Tb
✔✔Zoonotic disease - ✔✔diseases of animals that can be transmitted to humans
✔✔vector transmitted zoonotic disease - ✔✔diseases that are transmitted to humans by
an animal
✔✔emerging infections - ✔✔infectious diseases whose incidence in humans has
increased recently
✔✔Re-emerging diseases - ✔✔infectious diseases that were under control and are now
on the rise
✔✔Zika Emergence - ✔✔-First seen in Uganda in 1947 in a monkey
, -Transmitted by mosquito bite
-No treatment or vaccine is available
-Symptoms: fever, rash, joint pain, conjunctivitis
✔✔How do human activities increase emergence of disease? - ✔✔Global air travel;
moving great distances in short periods of time, moving microbes easily
✔✔Zika emergence in the US (2015) - ✔✔-5,754 cases reported
-Most were travel-associated
-229 local mosquito-borne (FL, TX)
-55 other case (52 sex, 2 lab, 1 unknown)
✔✔Lyme disease - ✔✔-Emerged in 1982
-From contact with wild or exotic animal species
-increased deer populations, deer mouse, and tick populaitons in proximity to human
habitation
✔✔Zoonoses - ✔✔Diseases of animals (reservior hosts) that may be transmitted ot
humans under natural conditions
Many have a vector (insects, ticks or mites)
Ex: Rabies, lyme disease, plague, West nile, Monkey pox
✔✔Monkey pox - ✔✔-Discoverd in 1958 in monkey colony
-First human case 1970 in DRC
-Human to human transmission from direct contact, respiratory tract or mucous
membranes (eye, nose, mouth)
-Similar to small pox but milder: fever, headaches, muscle aches, exhaustion, swollen
nodes, rash 1-3 days later
-Small pox vaccine offers some protection
✔✔Monkey pox virus in US - ✔✔-2003 outbreak in Marshfield Wisconsin
-Imported Gambian giant rats, prarie dogs as pets
-Pet dealer in texas brought infected rats
-Companies in texas suck up prarie dogs because they are a nucence to farming
-Rats and dogs had enough contact to be infected
-Prarie dogs bit and scratched infecting humans
-Banned imported rats to prevent disease spread
✔✔Challenges with Zika - ✔✔Can't tell who has it. Mosquito control, Population of
children with macrocephaly. Lack of access to birth control. How to distribute birth
control
✔✔Hantavirus Pulmonary Syndrome - ✔✔Outbreak in May 1993 in the four corner
region of the southwest US
