What is the ultimate concern for the nurse when administering a drug?
a. intensity of the response
b. dosage
c. route of administration
d. timing of administration
Give this one a try later!
a. intensity of the response (which is determined by the other factors)
Which statement about the percentage of oral drug absorption is true?
a. The percentage absorbed severely declines with age.
,b. The percentage absorbed increases with age.
c. The percentage absorbed decreases with age.
d. The percentage absorbed does not usually change with age.
Give this one a try later!
d. The percentage absorbed does not usually change with age.
The nurse is preparing to administer a dose of penicillin. Before administering the
medication, the nurse assesses the patient's allergy history. Which aspect of drug therapy
does this represent?
a. identifying high-risk patients
b. ensuring proper dosage
c. making PRN (as needed) decisions
d. evaluating therapeutic effects
Give this one a try later!
a. identifying high-risk patients
A new medication becomes available for treatment of a debilitating neurologic disease.
What would the nurse expect about the safety of the drug?
a. The drug has been tested in pregnant women
b. All possible adverse effects have been identified by animal testing
c. The drug has passed the FDA approval process
d. The drug is safe for administration to children
,Give this one a try later!
c. The drug has passed the FDA approval process
A nursing student is caring for a patient who has been taking morphine sulfate for pain
for 2 weeks. The nursing student shows an understanding of pharmacodynamic tolerance
by describing it to the instructor in what way?
a. "It is a form of tolerance that is a reduction in drug responsiveness brought on by
repeated dosing over a short period."
b. "It is a condition in which the patient requires increased doses of morphine sulfate to
achieve pain relief."
c. "It is a drug response caused by psychologic factors, not by biochemical or
physiological properties."
d. "It affects the minimum effective concentration."
Give this one a try later!
b. "It is a condition in which the patient requires increased doses of morphine
sulfate to achieve pain relief."
Pharmacodynamic tolerance is the phenomenon of decreased responsiveness
to a drug as a result of repeated drug administration. Tachyphylaxis is a
reduction in drug responsiveness as a result of repeated dosing over a short
time. Metabolic tolerance results from accelerated drug metabolism and not
repeated dosages; therefore, the minimum effective concentration is not
affected. The placebo effect is a drug response caused by psychologic
factors and not by the drug's biochemical or physiologic properties.
, Why does the nurse monitor the patient closely when administering a drug with a low
therapeutic index?
a. There is a low variability of responses to this drug.
b. The highest dose needed to produce a therapeutic effect is close to the lethal dose.
c. The average lethal dose of the drug is much higher than the therapeutic dose.
d. The dose required to produce a therapeutic response in 50% of patients is low.
Give this one a try later!
b. The highest dose needed to produce a therapeutic effect is close to the
lethal dose.
(A low therapeutic index indicates that the high doses needed to produce
therapeutic effects in some people may be large enough to cause death. A
high therapeutic index is more desirable, because the average lethal dose is
higher than the therapeutic dose. Low variability of responses to a drug is not
the definition of a low therapeutic index.)
The nurse is reviewing the laboratory value for a patient prescribed atorvastatin [Lipitor].
Which laboratory value is most useful for monitoring this drug?
a. Blood urea nitrogen (BUN)
b. Aspartate aminotransferase (AST)
c. C-reactive protein (CRP)
d. International normalized ratio (INR)
a. intensity of the response
b. dosage
c. route of administration
d. timing of administration
Give this one a try later!
a. intensity of the response (which is determined by the other factors)
Which statement about the percentage of oral drug absorption is true?
a. The percentage absorbed severely declines with age.
,b. The percentage absorbed increases with age.
c. The percentage absorbed decreases with age.
d. The percentage absorbed does not usually change with age.
Give this one a try later!
d. The percentage absorbed does not usually change with age.
The nurse is preparing to administer a dose of penicillin. Before administering the
medication, the nurse assesses the patient's allergy history. Which aspect of drug therapy
does this represent?
a. identifying high-risk patients
b. ensuring proper dosage
c. making PRN (as needed) decisions
d. evaluating therapeutic effects
Give this one a try later!
a. identifying high-risk patients
A new medication becomes available for treatment of a debilitating neurologic disease.
What would the nurse expect about the safety of the drug?
a. The drug has been tested in pregnant women
b. All possible adverse effects have been identified by animal testing
c. The drug has passed the FDA approval process
d. The drug is safe for administration to children
,Give this one a try later!
c. The drug has passed the FDA approval process
A nursing student is caring for a patient who has been taking morphine sulfate for pain
for 2 weeks. The nursing student shows an understanding of pharmacodynamic tolerance
by describing it to the instructor in what way?
a. "It is a form of tolerance that is a reduction in drug responsiveness brought on by
repeated dosing over a short period."
b. "It is a condition in which the patient requires increased doses of morphine sulfate to
achieve pain relief."
c. "It is a drug response caused by psychologic factors, not by biochemical or
physiological properties."
d. "It affects the minimum effective concentration."
Give this one a try later!
b. "It is a condition in which the patient requires increased doses of morphine
sulfate to achieve pain relief."
Pharmacodynamic tolerance is the phenomenon of decreased responsiveness
to a drug as a result of repeated drug administration. Tachyphylaxis is a
reduction in drug responsiveness as a result of repeated dosing over a short
time. Metabolic tolerance results from accelerated drug metabolism and not
repeated dosages; therefore, the minimum effective concentration is not
affected. The placebo effect is a drug response caused by psychologic
factors and not by the drug's biochemical or physiologic properties.
, Why does the nurse monitor the patient closely when administering a drug with a low
therapeutic index?
a. There is a low variability of responses to this drug.
b. The highest dose needed to produce a therapeutic effect is close to the lethal dose.
c. The average lethal dose of the drug is much higher than the therapeutic dose.
d. The dose required to produce a therapeutic response in 50% of patients is low.
Give this one a try later!
b. The highest dose needed to produce a therapeutic effect is close to the
lethal dose.
(A low therapeutic index indicates that the high doses needed to produce
therapeutic effects in some people may be large enough to cause death. A
high therapeutic index is more desirable, because the average lethal dose is
higher than the therapeutic dose. Low variability of responses to a drug is not
the definition of a low therapeutic index.)
The nurse is reviewing the laboratory value for a patient prescribed atorvastatin [Lipitor].
Which laboratory value is most useful for monitoring this drug?
a. Blood urea nitrogen (BUN)
b. Aspartate aminotransferase (AST)
c. C-reactive protein (CRP)
d. International normalized ratio (INR)
