UWSA 2 STEP 2 CERTIFICATION
SCRIPT 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
◍ Epidermoid Cyst presentation.
Answer: Discrete nodule under the skin from keratin lodged in the dermis,
just kinda looks like a solid lipoma
◍ 32 yo man with subQ nodule on his hand, larger nodule on achilles tendon,
and small yellow papules on his lower eyelid. What is decreased?.
Answer: Familial hypercholesterolemiaDecreased LDL R
◍ Decreased lipoprotein lipase.
Answer: Familial chylomicronemiaAt risk for acute pancreatitis
◍ Varicocele.
Answer: Chronic, distended pampiniform plexus within the spermatic cord,
presents with palpable bulge in groin and dull discomfort
◍ How do NSAIDs cause prerenal acute kidney injury (Mechanism).
Answer: Blockage of prostaglandin induced dilation of afferent arterioles :)
◍ Defective ApoE.
Answer: Familial dysbetalipoproteinemiaIncreases chylomicron and VLDL
remnants
◍ A 32 yo male presents to clinic with occasional mid-abdominal pain that is
gnawing. It wakes him up during the night and dan be relieved by eating a
light meal. What should you test for?.
Answer: Urease--> H. pylori
◍ Patient from Eastern Europe has increasing dyspnea. She has a noctural
cough and blood-tinged sputum. When the patient lies in the LLD position
, and exhales fully, there is a low-pitched, mid-diastolic murmur at the
cardiac apex. Cause?.
Answer: MS--> Rheumatic fever
◍ Bile leak presentation after lap chole.
Answer: RUQ Tenderness, low grade fever, nausea, and vomiting 2-10 days
after surgery, with leukocytosis and obstructive liver enzymes
◍ STK11 gene mutation.
Answer: Peutz-Jegher syndrome
◍ Liposarcoma.
Answer: Round cells with multiple mitoses that create a painful lesion.
Cause nuclear indentations and scalloping of the nuclear membrane.
◍ What do liver enzymes do in tylenol overdose.
Answer: >3000 damn
◍ What type of bilirubin is associated with gilbert.
Answer: Unconjugated
◍ Desmoid tumors.
Answer: Benign growths composed of broad fasicles and rounded
fibroblasts with abundant cytoplasm
◍ Guianne barre CSF Findings.
Answer: Increased protein with normal cell count (albuminocytologic
dissociation)
◍ Intertrigo.
Answer: Inflammatory condition involving skin folds, axilla, or abdominal
folds caused by candidaTypically like fat people with skin infection under
the boobs or in the arm pits
◍ Fibrosarcomas.
Answer: Marked diarray, pleomorphism, mitotic activity, hemorrhage, and
necrosis
◍ Lipoma.
, Answer: SubQ nodules that car composed on mature fat cells without
pleomorphism
◍ Where are immunoglobulin deposits in pemphigus vulgaris?.
Answer: Between keratinocytes--> anti-desmosomes which form
desmosomal junctions
◍ Intetrigo diagnosis.
Answer: KOH Prep shows pseudohyphae with budding yeast forms
(candida)
◍ Erythrasma.
Answer: skin infection of intertriginal areas ffrom corneybacterium
mintissimum wel demarcated red/brown plaques and wrinkling diagnose
with woods lamp
◍ Baby with congenital infection and you aren't sure which one (which is the
most common cause).
Answer: CMV Infection apparently (periventricular calcifications)
◍ Deposits of IgG autoantibodies against the BM.
Answer: Bullous pemphigoid
◍ A lesion where causes Horner's syndrome?.
Answer: Cervical chain ganglion
◍ Ciliary ganglion.
Answer: Controls CN III
◍ Patient with a long history of alcohol abuse comes to the ED due to frequent
falls. He feels unsteady, has blurred vision, and has a course postural tremor.
Where is the lesion?.
Answer: Cerebellum Alcoholic cerebellar degeneration--> most prominent
in the cerebellar vermis.
◍ congenital parvovirus infection presentation.
Answer: severe anemia and hydrops
◍ Defect with nephrogenic diabetes insipidus.
SCRIPT 2026 QUESTIONS WITH
SOLUTIONS GRADED A+
◍ Epidermoid Cyst presentation.
Answer: Discrete nodule under the skin from keratin lodged in the dermis,
just kinda looks like a solid lipoma
◍ 32 yo man with subQ nodule on his hand, larger nodule on achilles tendon,
and small yellow papules on his lower eyelid. What is decreased?.
Answer: Familial hypercholesterolemiaDecreased LDL R
◍ Decreased lipoprotein lipase.
Answer: Familial chylomicronemiaAt risk for acute pancreatitis
◍ Varicocele.
Answer: Chronic, distended pampiniform plexus within the spermatic cord,
presents with palpable bulge in groin and dull discomfort
◍ How do NSAIDs cause prerenal acute kidney injury (Mechanism).
Answer: Blockage of prostaglandin induced dilation of afferent arterioles :)
◍ Defective ApoE.
Answer: Familial dysbetalipoproteinemiaIncreases chylomicron and VLDL
remnants
◍ A 32 yo male presents to clinic with occasional mid-abdominal pain that is
gnawing. It wakes him up during the night and dan be relieved by eating a
light meal. What should you test for?.
Answer: Urease--> H. pylori
◍ Patient from Eastern Europe has increasing dyspnea. She has a noctural
cough and blood-tinged sputum. When the patient lies in the LLD position
, and exhales fully, there is a low-pitched, mid-diastolic murmur at the
cardiac apex. Cause?.
Answer: MS--> Rheumatic fever
◍ Bile leak presentation after lap chole.
Answer: RUQ Tenderness, low grade fever, nausea, and vomiting 2-10 days
after surgery, with leukocytosis and obstructive liver enzymes
◍ STK11 gene mutation.
Answer: Peutz-Jegher syndrome
◍ Liposarcoma.
Answer: Round cells with multiple mitoses that create a painful lesion.
Cause nuclear indentations and scalloping of the nuclear membrane.
◍ What do liver enzymes do in tylenol overdose.
Answer: >3000 damn
◍ What type of bilirubin is associated with gilbert.
Answer: Unconjugated
◍ Desmoid tumors.
Answer: Benign growths composed of broad fasicles and rounded
fibroblasts with abundant cytoplasm
◍ Guianne barre CSF Findings.
Answer: Increased protein with normal cell count (albuminocytologic
dissociation)
◍ Intertrigo.
Answer: Inflammatory condition involving skin folds, axilla, or abdominal
folds caused by candidaTypically like fat people with skin infection under
the boobs or in the arm pits
◍ Fibrosarcomas.
Answer: Marked diarray, pleomorphism, mitotic activity, hemorrhage, and
necrosis
◍ Lipoma.
, Answer: SubQ nodules that car composed on mature fat cells without
pleomorphism
◍ Where are immunoglobulin deposits in pemphigus vulgaris?.
Answer: Between keratinocytes--> anti-desmosomes which form
desmosomal junctions
◍ Intetrigo diagnosis.
Answer: KOH Prep shows pseudohyphae with budding yeast forms
(candida)
◍ Erythrasma.
Answer: skin infection of intertriginal areas ffrom corneybacterium
mintissimum wel demarcated red/brown plaques and wrinkling diagnose
with woods lamp
◍ Baby with congenital infection and you aren't sure which one (which is the
most common cause).
Answer: CMV Infection apparently (periventricular calcifications)
◍ Deposits of IgG autoantibodies against the BM.
Answer: Bullous pemphigoid
◍ A lesion where causes Horner's syndrome?.
Answer: Cervical chain ganglion
◍ Ciliary ganglion.
Answer: Controls CN III
◍ Patient with a long history of alcohol abuse comes to the ED due to frequent
falls. He feels unsteady, has blurred vision, and has a course postural tremor.
Where is the lesion?.
Answer: Cerebellum Alcoholic cerebellar degeneration--> most prominent
in the cerebellar vermis.
◍ congenital parvovirus infection presentation.
Answer: severe anemia and hydrops
◍ Defect with nephrogenic diabetes insipidus.
