Advanced Pharmacology Final Exam Review ACTUAL UPDATED QUESTIONS
AND CORRECT ANSWERS
Why are nitrate-free periods every 24 hours necessary To inhibit the development of tolerance
for the patient on nitroglycerin therapy?
What does a low level of thyroid-stimulating hormone Hyperthroidism
indicate?
What would be the best option to treat a newly Propanolol (Inderal)
diagnosed patient with a low TSH level with?
Spironoaldactone (Aldactone) has what mechanism of Aldosterone antagonist
action (MOA)?
Heparin exerts its therapeutic action by what? Upregulating the activity of one of the body's natural anticoagulant molecules,
antithrombin III
What physiologic action happens when the offending Mast cells liberate large doses of histamine.
drug is administered during an anaphylactic reaction.
What are two systemic psoriasis medications? Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of Thiazide diuretics
patients with uncomplicated stage I hypertension?
What is the effect of cardiac glycosides? Digitalis glycosides have a negative chronotropic effect on the cardiac muscle
cells.
, Amenorrhea is the most common side effect of which Medroxyprogesterone (Depo-Provera)
birth control medication?
What is an anti-hypertensive agent which competes with Atenolol (Tenormin)
epinephrine for available beta-receptor sites?
What type of action does nitrates have on the body? Reduction in systemic venous tone.
What is the recommended level of low-density 100mg/dl or less.
lipoprotein cholesterol (LDL) for patients with known
coronary artery disease?
What is the MOA of group IV anti-dysrhythmia drugs? Depressing phase 4 depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum Anti-thyroid drugs.
concentration of thyroid hormones and re-establish
eumetabolic state in a patient with Graves' disease?
Which type of diuretic would be used for a stage I Loop diuretic.
hypertension in a patient with renal insufficiency?
What drug should be considered as first-line therapy for Enalapril (Vasotec)
a client with hypertension and heart failure?
Which drug is considered safe for hypertension treatment Methyldopa (Aldomet)
during pregnancy?
What drug will reduce afterload because it is an alpha- Prazosin (Minipress)
adrenergic blocker?
What is an expected effect of the use of a beta- Reduced force of cardiac contraction.
adrenergic blocker to control angina?
What side effect should be monitored closely in the Lactic acidosis.
elderly when taking Metformin (Glucophage) for type 2
diabetes?
What is the primary role of cytochrome p-450 in the Deactivate and detoxify medications and other substances.
liver?
What is a component of Vitamin K-dependent clotting Prothrombin
factors?
How are IV morphine and nitroglycerin beneficial in Decrease preload.
acute heart failure?
What is the purpose of administering a vasodilating drug Decrease afterload.
to a patient in heart failure?
AND CORRECT ANSWERS
Why are nitrate-free periods every 24 hours necessary To inhibit the development of tolerance
for the patient on nitroglycerin therapy?
What does a low level of thyroid-stimulating hormone Hyperthroidism
indicate?
What would be the best option to treat a newly Propanolol (Inderal)
diagnosed patient with a low TSH level with?
Spironoaldactone (Aldactone) has what mechanism of Aldosterone antagonist
action (MOA)?
Heparin exerts its therapeutic action by what? Upregulating the activity of one of the body's natural anticoagulant molecules,
antithrombin III
What physiologic action happens when the offending Mast cells liberate large doses of histamine.
drug is administered during an anaphylactic reaction.
What are two systemic psoriasis medications? Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of Thiazide diuretics
patients with uncomplicated stage I hypertension?
What is the effect of cardiac glycosides? Digitalis glycosides have a negative chronotropic effect on the cardiac muscle
cells.
, Amenorrhea is the most common side effect of which Medroxyprogesterone (Depo-Provera)
birth control medication?
What is an anti-hypertensive agent which competes with Atenolol (Tenormin)
epinephrine for available beta-receptor sites?
What type of action does nitrates have on the body? Reduction in systemic venous tone.
What is the recommended level of low-density 100mg/dl or less.
lipoprotein cholesterol (LDL) for patients with known
coronary artery disease?
What is the MOA of group IV anti-dysrhythmia drugs? Depressing phase 4 depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum Anti-thyroid drugs.
concentration of thyroid hormones and re-establish
eumetabolic state in a patient with Graves' disease?
Which type of diuretic would be used for a stage I Loop diuretic.
hypertension in a patient with renal insufficiency?
What drug should be considered as first-line therapy for Enalapril (Vasotec)
a client with hypertension and heart failure?
Which drug is considered safe for hypertension treatment Methyldopa (Aldomet)
during pregnancy?
What drug will reduce afterload because it is an alpha- Prazosin (Minipress)
adrenergic blocker?
What is an expected effect of the use of a beta- Reduced force of cardiac contraction.
adrenergic blocker to control angina?
What side effect should be monitored closely in the Lactic acidosis.
elderly when taking Metformin (Glucophage) for type 2
diabetes?
What is the primary role of cytochrome p-450 in the Deactivate and detoxify medications and other substances.
liver?
What is a component of Vitamin K-dependent clotting Prothrombin
factors?
How are IV morphine and nitroglycerin beneficial in Decrease preload.
acute heart failure?
What is the purpose of administering a vasodilating drug Decrease afterload.
to a patient in heart failure?
