NR566 FY25 MIDTERM EXAM WEEK 1, 2,
3 AND 4 STUDY GUIDE WITH 100%
COMPLETE SOLUTION
Advanced Pharmacology - Care of the Family (Chamberlain
University)
, NR566 Midterm Study Guide
This study guide covers content for the question bank for this course. There are 100 questions
on the exam and more content in the exam study bank than will be seen on any given exam.
Therefore, you may note more than 100 topic items noted in this study guide. However, there
may also be more than one question for a topic listed so you should know each one well. Some
items listed are more specific than others. If the item listed seems vague, if it’s a more general
question and to be more specific would be to risk the integrity of the question itself.
Number of Questions on Exam: 100
Point Value of Each Question:2
Styles of Questions of Exam: Multiple Choice Only
Knowledge Levels: Various (remember, understand,
apply)
Time Limit: 150 minutes
Number of Attempts: 1
Use of Support Materials: Not Allowed
Platform Used for Exam: Exam Soft/Examplify
Exam Expectations: Review Exam Expectations in
Course Announcements
Tips on Using this Study Guide
1. Review the topics each week to take notes as you move through the course and focus your
reading and content review in the course.
2. You can make notes directly on each tab for the respective week or print out and hand
write your notes.
3. If you choose to print, you will want to adjust the size of columns so the table width will fit
on a printed page.
4. Re-write your notes if you type them to connect the content to your memory more readily
as the activity of writing and saying it again as you write it creates repetition that helps
commit the content to memory.
5. Create your own practice questions that are clinical scenario based to move the content
from a memorization (Remember) level of learning to an application type of learning. Much
of your exam will be at the application level so it's not enough to memorize your notes.
6. Review your study guide and notes as often as you can. Read them out loud so you hear
the words externally as well as internally. The more senses you can engage while studying,
the more likely you are to remember it.
, Week 1
Chapter 79 Chapter 80
• Itraconazole Drug Interactions • Oseltamivir (Tamiflu) MOA
• Therapeutic Uses of Caspofungin • Oseltamivir (Tamiflu)
• Griseofulvin Indications Administration
• Oral terbinafine Indications • Oseltamivir (Tamiflu) Indications
• Azole Use in Older Adults • Acyclovir: Route of
• Pharmacokinetics of Amphotericin Administration
B Considerations
• Treatment Choice for • Purpose of Annual Flu Vaccine
Systemic Mycoses • Flu Vaccine: Contraindications
• Drug Interaction with Itraconazole • Palivizumab Indications
• Adverse Effects of Caspofungin • Acyclovir Indication
• Tinea Pedis Treatment • Acyclovir MOA
• Amphotericin B:
Minimizing
Nephrotoxicity
• Griseofulvin Indications
• Azole Use in Older Adults
Chapter 81 Chapter 83
• Protease inhibitors (PIs): • Mebendazole MOA
Adverse Effects • Enterobiasis Treatment Choices
• Integrase Strand Transfer • Albendazole MOA
Inhibitors (INSTIs): MOA
• NRTIs Adverse Effects
• protease inhibitors (PIs): MOA
• NRTIs MOA
• Chemokine Receptor 5
Antagonists (CCR5
antagonists): MOA
• Integrase Strand Transfer
Inhibitors (INSTIs): Adverse
Effects
• protease inhibitors (PIs):
Adverse Effects
• protease inhibitors (PIs):
Prescribing considerations
• NRTIs MOA
• NRTIs Adverse Effects
• NRTIs MOA
, Chapter 79
1. Itraconazole Drug Interactions
• Mechanism: Itraconazole inhibits the CYP3A4 enzyme, leading to potential
interactions with many other drugs.
• Examples of Common Medications and Interactions:
o Statins (e.g., simvastatin): Increased risk of myopathy and
rhabdomyolysis. Consider avoiding or switching to a non-interacting
statin like pravastatin.
o Calcium Channel Blockers (e.g., verapamil, diltiazem): Risk of
congestive heart failure due to additive negative inotropic effects.
o Warfarin: Increases INR and bleeding risk. Requires close INR
monitoring if used concurrently.
• Clinical Recommendations: Evaluate the need for itraconazole when
patients are on interacting drugs. Consider alternative antifungals or adjust
doses.
2. Therapeutic Uses of Caspofungin
• Primary Indications:
o Invasive Candidiasis: Effective against most Candida species, especially
useful for
C. glabrata and C. krusei, which are resistant to azoles.
o Invasive Aspergillosis: Second-line option for patients who cannot
tolerate or do not respond to amphotericin B or voriconazole.
• Example Medications: Caspofungin (Cancidas).
• Dosing and Duration: 70 mg loading dose, then 50 mg daily; duration
depends on infection severity and response to therapy.
3. Griseofulvin Indications
• Common Uses: Dermatophyte infections, especially when caused by
Microsporum and Trichophyton species.
• Indications:
o Tinea Capitis: Often used in children as it is effective against scalp
infections.
o Tinea Corporis and Tinea Cruris: Alternative option when topical
treatments are ineffective.
• Example Medications: Griseofulvin (Grifulvin V, Gris-PEG).
• Clinical Considerations: Requires several weeks to months of therapy
depending on the location and severity of the infection.
3 AND 4 STUDY GUIDE WITH 100%
COMPLETE SOLUTION
Advanced Pharmacology - Care of the Family (Chamberlain
University)
, NR566 Midterm Study Guide
This study guide covers content for the question bank for this course. There are 100 questions
on the exam and more content in the exam study bank than will be seen on any given exam.
Therefore, you may note more than 100 topic items noted in this study guide. However, there
may also be more than one question for a topic listed so you should know each one well. Some
items listed are more specific than others. If the item listed seems vague, if it’s a more general
question and to be more specific would be to risk the integrity of the question itself.
Number of Questions on Exam: 100
Point Value of Each Question:2
Styles of Questions of Exam: Multiple Choice Only
Knowledge Levels: Various (remember, understand,
apply)
Time Limit: 150 minutes
Number of Attempts: 1
Use of Support Materials: Not Allowed
Platform Used for Exam: Exam Soft/Examplify
Exam Expectations: Review Exam Expectations in
Course Announcements
Tips on Using this Study Guide
1. Review the topics each week to take notes as you move through the course and focus your
reading and content review in the course.
2. You can make notes directly on each tab for the respective week or print out and hand
write your notes.
3. If you choose to print, you will want to adjust the size of columns so the table width will fit
on a printed page.
4. Re-write your notes if you type them to connect the content to your memory more readily
as the activity of writing and saying it again as you write it creates repetition that helps
commit the content to memory.
5. Create your own practice questions that are clinical scenario based to move the content
from a memorization (Remember) level of learning to an application type of learning. Much
of your exam will be at the application level so it's not enough to memorize your notes.
6. Review your study guide and notes as often as you can. Read them out loud so you hear
the words externally as well as internally. The more senses you can engage while studying,
the more likely you are to remember it.
, Week 1
Chapter 79 Chapter 80
• Itraconazole Drug Interactions • Oseltamivir (Tamiflu) MOA
• Therapeutic Uses of Caspofungin • Oseltamivir (Tamiflu)
• Griseofulvin Indications Administration
• Oral terbinafine Indications • Oseltamivir (Tamiflu) Indications
• Azole Use in Older Adults • Acyclovir: Route of
• Pharmacokinetics of Amphotericin Administration
B Considerations
• Treatment Choice for • Purpose of Annual Flu Vaccine
Systemic Mycoses • Flu Vaccine: Contraindications
• Drug Interaction with Itraconazole • Palivizumab Indications
• Adverse Effects of Caspofungin • Acyclovir Indication
• Tinea Pedis Treatment • Acyclovir MOA
• Amphotericin B:
Minimizing
Nephrotoxicity
• Griseofulvin Indications
• Azole Use in Older Adults
Chapter 81 Chapter 83
• Protease inhibitors (PIs): • Mebendazole MOA
Adverse Effects • Enterobiasis Treatment Choices
• Integrase Strand Transfer • Albendazole MOA
Inhibitors (INSTIs): MOA
• NRTIs Adverse Effects
• protease inhibitors (PIs): MOA
• NRTIs MOA
• Chemokine Receptor 5
Antagonists (CCR5
antagonists): MOA
• Integrase Strand Transfer
Inhibitors (INSTIs): Adverse
Effects
• protease inhibitors (PIs):
Adverse Effects
• protease inhibitors (PIs):
Prescribing considerations
• NRTIs MOA
• NRTIs Adverse Effects
• NRTIs MOA
, Chapter 79
1. Itraconazole Drug Interactions
• Mechanism: Itraconazole inhibits the CYP3A4 enzyme, leading to potential
interactions with many other drugs.
• Examples of Common Medications and Interactions:
o Statins (e.g., simvastatin): Increased risk of myopathy and
rhabdomyolysis. Consider avoiding or switching to a non-interacting
statin like pravastatin.
o Calcium Channel Blockers (e.g., verapamil, diltiazem): Risk of
congestive heart failure due to additive negative inotropic effects.
o Warfarin: Increases INR and bleeding risk. Requires close INR
monitoring if used concurrently.
• Clinical Recommendations: Evaluate the need for itraconazole when
patients are on interacting drugs. Consider alternative antifungals or adjust
doses.
2. Therapeutic Uses of Caspofungin
• Primary Indications:
o Invasive Candidiasis: Effective against most Candida species, especially
useful for
C. glabrata and C. krusei, which are resistant to azoles.
o Invasive Aspergillosis: Second-line option for patients who cannot
tolerate or do not respond to amphotericin B or voriconazole.
• Example Medications: Caspofungin (Cancidas).
• Dosing and Duration: 70 mg loading dose, then 50 mg daily; duration
depends on infection severity and response to therapy.
3. Griseofulvin Indications
• Common Uses: Dermatophyte infections, especially when caused by
Microsporum and Trichophyton species.
• Indications:
o Tinea Capitis: Often used in children as it is effective against scalp
infections.
o Tinea Corporis and Tinea Cruris: Alternative option when topical
treatments are ineffective.
• Example Medications: Griseofulvin (Grifulvin V, Gris-PEG).
• Clinical Considerations: Requires several weeks to months of therapy
depending on the location and severity of the infection.
