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MATERIAL PHARMACOLOGY PRINCIPLES NUR 210 VERIFIED VERSION OF -- EXAM With comprehensive Questions and Well Elaborated Correct Answers GRADED A+.

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MATERIAL PHARMACOLOGY PRINCIPLES NUR 210 VERIFIED VERSION OF -- EXAM With comprehensive Questions and Well Elaborated Correct Answers GRADED A+.

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MATERIAL PHARMACOLOGY
PRINCIPLES NUR 210 VERIFIED
VERSION OF {2026-2027} EXAM With
comprehensive Questions and Well
Elaborated Correct Answers GRADED
A+
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,drug response - correct ans:the intensity of the drug response is directly related to the concentration of
the drug at the SITE OF ACTION



Goal is to:

- maximize the beneficial effects- concentration high enough for desired response

- minimize harm- avoid to high a concentration



Three phases of drug action - correct ans:1. pharmaceutic phase (dissolution)

2. pharmacokinetic phase (drug moving through the body)

3. pharmacodynamic phase (what the drug does to the body)



1. pharmaceutic phase - correct ans:the drug goes into solution



- Dissolution: the process by which a drug goes into solution and becomes available for absorption



- must be dissolved before it can be absorbed

- most absorption takes place in the small intestine



2. pharmacokinetic phase: four processes - correct ans:"what the BODY does to the drug"

- absorption

- distribution

- metabolism/ biotransformation

- exertion



pharmacokinetic phase: Absorption - correct ans:(small intestine) the movement of a drug from its site
of administration into the blood



pharmacokinetic phase: Distribution - correct ans:drug moves from blood --> cell membrane

, pharmacokinetic phase: Metabolism/biotransformation - correct ans:lipid soluble metabolite (liver) --> a
water soluble metabolite



pharmacokinetic phase: Excretion - correct ans:water soluble metabolite (kidneys)



liver - correct ans:breaks down the drug



kidneys - correct ans:excretes the drug



Pharmacokinetic phase movement process - correct ans:orally --> stomach --> SI --> bloodstream --> site
of action --> liver (broken down) --> kidneys (excreted)



IV --> bloodstream --> cite of action --> liver --> kidneys



drugs crossing the cell membranes phospholipid cell layer - correct ans:-drugs must be LIPID SOLUBLE in
order to pass through the membrane



- WATER SOLUBLE drugs penetrate the cell membrane through channels and pores



Absorption



1. direct penetration of the membranes

2. channels and pores

3. transport systems - correct ans:the movement of a drug from its site of administration to the blood



How do drugs cross membranes?



1. Direct penetration of the membranes - correct ans:- use by MOST drugs

- most drugs to large to pass thru channels and pores

- most drugs lack transport systems

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