NSG 5240 ADVANCED PHARMACOLOGY FINAL
EXAM 2026-2027 QUESTIONS AND CORRECT
ANSWERS GRADED A+
Charlie is a 65-year-old male who has been diagnosed with hypertension and
benign prostatic hyperplasia. Doxazosin has been chosen to treat his hypertension
because it:
1. Increases peripheral vasoconstriction
2. Decreases detrusor muscle contractility
3. Lowers supine blood pressure more than standing pressure
4. Relaxes smooth muscle in the bladder neck
4. Relaxes smooth muscle in the bladder neck
To reduce potential adverse effects, patients taking a peripherally acting alpha1
antagonist should do all of the following EXCEPT:
1. Take the dose at bedtime
2. Sit up slowly and dangle their feet before standing
3. Monitor their blood pressure and skip a dose if the pressure is less than 120/80
4. Weigh daily and report weight gain of greater than 2 pounds in one day
3. Monitor their blood pressure and skip a dose if the pressure is less than 120/80
,John has clonidine, a centrally acting adrenergic blocker, prescribed for his
hypertension. He should:
1. Not miss a dose or stop taking the drug because of potential rebound
hypertension
2. Increase fiber in the diet to treat any diarrhea that may occur
3. Reduce fluid intake to less than 2 liters per day to prevent fluid retention
4. Avoid sitting for long periods, as this can lead to deep vein thrombosis
1. Not miss a dose or stop taking the drug because of potential rebound
hypertension
Clonidine has several off-label uses, including:
1. Alcohol and nicotine withdrawal
2. Post-herpetic neuralgia
3. Both 1 and 2
4. Neither 1 nor 2
3. Both 1 and 2
Combined alpha-beta antagonists are used to reduce the progression of heart failure
because they:
1. Vasodilate the peripheral vasculature
2. Decrease cardiac output
3. Increase renal vascular resistance
4. Reduce atherosclerosis secondary to elevated serum lipoproteins
1. Vasodilate the peripheral vasculature
,Carvedilol is heavily metabolized by CYP2D6 and 2C9, resulting in drug
interactions with which of the following drug classes?
1. Histamine 2 blockers
2. Quinolones
3. Serotonin re-uptake inhibitors
4. All of the above
4. All of the above
Alpha-beta blockers are especially effective to treat hypertension for which ethnic
group?
1. White
2. Asian
3. African American
4. Native American
3. African American
Bethanechol:
1. Increases detrusor muscle tone to empty the bladder
2. Decreases gastric acid secretion to treat peptic ulcer disease
3. Stimulates voluntary muscle tone to improve strength
4. Reduces bronchial airway constriction to treat asthma
1. Increases detrusor muscle tone to empty the bladder
, Clinical dosing of Bethanechol:
1. Begins at the highest effective dose to obtain a rapid response
2. Starts at 5 mg to 10 mg PO and is repeated every hour until a satisfactory
clinical response is achieved
3. Requires dosing only once daily
4. Is the same for both the oral and parenteral route
2. Starts at 5 mg to 10 mg PO and is repeated every hour until a satisfactory
clinical response is achieved
Patients who need to remain alert are taught to avoid which drug due to its
antimuscarinic effects?
1. Levothyroxine
2. Prilosec
3. Dulcolax
4. Diphenhydramine
4. Diphenhydramine
Anticholinesterase inhibitors are used to treat:
1. Peptic ulcer disease
2. Myasthenia gravis
3. Both 1 and 2
4. Neither 1 nor 2
EXAM 2026-2027 QUESTIONS AND CORRECT
ANSWERS GRADED A+
Charlie is a 65-year-old male who has been diagnosed with hypertension and
benign prostatic hyperplasia. Doxazosin has been chosen to treat his hypertension
because it:
1. Increases peripheral vasoconstriction
2. Decreases detrusor muscle contractility
3. Lowers supine blood pressure more than standing pressure
4. Relaxes smooth muscle in the bladder neck
4. Relaxes smooth muscle in the bladder neck
To reduce potential adverse effects, patients taking a peripherally acting alpha1
antagonist should do all of the following EXCEPT:
1. Take the dose at bedtime
2. Sit up slowly and dangle their feet before standing
3. Monitor their blood pressure and skip a dose if the pressure is less than 120/80
4. Weigh daily and report weight gain of greater than 2 pounds in one day
3. Monitor their blood pressure and skip a dose if the pressure is less than 120/80
,John has clonidine, a centrally acting adrenergic blocker, prescribed for his
hypertension. He should:
1. Not miss a dose or stop taking the drug because of potential rebound
hypertension
2. Increase fiber in the diet to treat any diarrhea that may occur
3. Reduce fluid intake to less than 2 liters per day to prevent fluid retention
4. Avoid sitting for long periods, as this can lead to deep vein thrombosis
1. Not miss a dose or stop taking the drug because of potential rebound
hypertension
Clonidine has several off-label uses, including:
1. Alcohol and nicotine withdrawal
2. Post-herpetic neuralgia
3. Both 1 and 2
4. Neither 1 nor 2
3. Both 1 and 2
Combined alpha-beta antagonists are used to reduce the progression of heart failure
because they:
1. Vasodilate the peripheral vasculature
2. Decrease cardiac output
3. Increase renal vascular resistance
4. Reduce atherosclerosis secondary to elevated serum lipoproteins
1. Vasodilate the peripheral vasculature
,Carvedilol is heavily metabolized by CYP2D6 and 2C9, resulting in drug
interactions with which of the following drug classes?
1. Histamine 2 blockers
2. Quinolones
3. Serotonin re-uptake inhibitors
4. All of the above
4. All of the above
Alpha-beta blockers are especially effective to treat hypertension for which ethnic
group?
1. White
2. Asian
3. African American
4. Native American
3. African American
Bethanechol:
1. Increases detrusor muscle tone to empty the bladder
2. Decreases gastric acid secretion to treat peptic ulcer disease
3. Stimulates voluntary muscle tone to improve strength
4. Reduces bronchial airway constriction to treat asthma
1. Increases detrusor muscle tone to empty the bladder
, Clinical dosing of Bethanechol:
1. Begins at the highest effective dose to obtain a rapid response
2. Starts at 5 mg to 10 mg PO and is repeated every hour until a satisfactory
clinical response is achieved
3. Requires dosing only once daily
4. Is the same for both the oral and parenteral route
2. Starts at 5 mg to 10 mg PO and is repeated every hour until a satisfactory
clinical response is achieved
Patients who need to remain alert are taught to avoid which drug due to its
antimuscarinic effects?
1. Levothyroxine
2. Prilosec
3. Dulcolax
4. Diphenhydramine
4. Diphenhydramine
Anticholinesterase inhibitors are used to treat:
1. Peptic ulcer disease
2. Myasthenia gravis
3. Both 1 and 2
4. Neither 1 nor 2
