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PHARMACOLOGY_CONNECTIONS_TO_NURSING_PRACTICE_5TH_EDITION_MICHAEL

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PHARMACOLOGY CONNECTIONS TO
NURSING PRACTICE 5TH EDITION
MICHAEL ADAMS CAROL URBAN ACTUAL
TEST PAPER 2026 QUESTIONS WITH
ANSWERS GRADED A+

⩥ acetaminophen. Answer: centrally acting cox inhibitor; analgesic and
antipyretic properties; no antiinflammatory,antirheumatic properties


⩥ acyclovir. Answer: Antimetabolite for Treating Herpes Simplex Virus
& Varicella-Zoster Virus Infections;
MOAs: Purine necleoside analog: DNA polymerase inhibitor, suppresses
synthesis of viral DNA, resistance.


⩥ amiodarone. Answer: Class 3 Potassium channel blocker
Only approved for life-threatening dysrhythmias.
Delays repolarization and extends action potential of heart muscle cells.
SE: Profound hypotension."


⩥ amoxicillin. Answer: Broad-spectrum penicillin active against H.
influenzae, E. coli, and N. Gonorrhoeae. It is inactivated by beta-
lactamases, so not helpful for Staphylococcus.

,⩥ atropine. Answer: muscinarinic receptor antagonist/anticholinergic
drug; used for mydriases (eye exams), to raise HR, lower GI motility,
and as antidote to muscarinic poisoning (rx, shrooms)


⩥ amphotericin B. Answer: broad spectrum antifungal, which is the
agent of choice for systemic mycoses, despite being highly toxic. Its
uses are limited to treating progressive and potentially fatal infections.
Adverse effects include infusion reactions, nephrotoxicity, and
hypokalemia.


⩥ aspirin. Answer: A drug that decrease platelet aggregation and is used
to prevent arterial thrombosis, stroke, or MI. Major SEs include risk of
major GI bleeding. This drug is an NSAID that works by inhibiting
platelet COX, COX-1, and COX-2.


⩥ beclomethasone. Answer: inhaled corticosteroid used to treat airway
inflammation in asthma


⩥ bethanechol. Answer: muscarinic agnonist, used primarily for urinary
retention


⩥ buproprion. Answer: (DA and NE). Weight loss, seizure, insomnia,
headache, serotonin syndrome (see laundry list above), withdrawal,
Neonatal Abstinence Syndrome

, ⩥ captopril. Answer: ACE inhibitor - shown to have efficacious effects
in treating a patient with heart failure. Blocks production of angiotensin
II, dilates arterioles and veins, and decreases release of aldosterone. It
may show the adverse effects of hypotension, hyperkalemia, or
persistant cough, CARDIAC REMODELING


⩥ carbenicillin. Answer: "Extended spectrum (antipseudomonal
penicillins), which has the same spectrum of activity as broad-spectrum
penicillins, plus treatment of Pseudomonas aeruginosa


⩥ cefotaxime. Answer: "Third generation cephalosporin with activity
against meningitis and nosocomial infections resistant to others
(restricted use). It has greater activity against Gram negative bacteria,
increased resistance to beta-lactamases, and better ability to reach CSF.


⩥ cephalexin. Answer: "First generation cephalosporin poor activity
against Gram negative bacteria, sensitive to to most beta-lactamases,
unable to reach CSF. Used for Staphylococcus if mild penicillin allergy.


⩥ celecoxib. Answer: 2nd Generation Nonsteroidal Antiinflammatory
Drug (COX-2 Selective NSAID); AE: risk of CV events, warfarin may
be more effective with celecoxib


⩥ cholestyramine. Answer: Inhibits bile reabsorption in intenstine,
increases LDL receptors in liver, accelerates bile excretion. Many of the
adverse effects result from the drug not being absorbed from GI,

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