Clayton’s Basic Pharmacology for Nurses (20th Ed, ISBN 9780443126994) – Test Bank + Answers

TestBank For Clayton’s Basic PharmacologyforNurses 19th Edition
c3 c3 c3 c3 c3 c3 c3 c3 c3 1


Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
c3 c3 c3 c3 c3 c3 c3 c3




Clayton’sBasicPharmacology forNurses,19thEdition
c3 c3 c3 c3 c3 c3 c3




MULTIPLECHOICE c3




1. Whichnameidentifies adruglisted bythe US Food and
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




Drug Administration (FDA)?
c3 c3 c3




a. Brand
b. Nonproprietary
c. Official
d. Trademark

ANS: C c 3




The official name is the name under which a drug is listed by the
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




FDA. The brand name, or trademark, is the name given to a drug
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




by its manufacturer. The nonproprietary, or generic, name is
c3 c3 c3 c3 c3 c3 c3 c3 c3




provided by the United States Adopted Names Council.
c3 c3 c3 c3 c3 c3 c3 c3




DIF: CognitiveLevel:Knowledge REF: p. 9 c3 c3 c 3 c3




OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care c3 c3 c3 c3 c3 c3 c3 c3




Environment TOP: Nursing Process Step: Assessment
c3 CON: c3 c 3 c3 c3 c3




Patient Education
c3 c3




2. Whichsourcecontains information specificto nutritional supplements?
c3 c3 c3 c3 c3 c3 c3




a. USPDictionary of USAN &International Drug Names c3 c3 c3 c3 c3 c3 c3




b. NaturalMedicinesComprehensiveDatabase c3 c3 c3




c. UnitedStatesPharmacopoeia/NationalFormulary (USPNF) c3 c3 c3 c3 c3




d. DrugInteractionFacts c3 c3




ANS: C c 3




UnitedStatesPharmacopoeia/NationalFormularycontainsinformationspecifictonutritional
c3 c3 c3 c3 c3 c3 c3 c3




supplements. USP Dictionary of USAN &International Drug Names is a compilation of drug
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




names, pronunciation guide, and possible future FDA approved drugs; it does not include
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




nutritional supplements. Natural Medicines Comprehensive Database contains
c3 c3 c3 c3 c3 c3 c3




evidence-based informationonherbalmedicines andherbal combinationproducts;itdoesnot c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




include information specific to nutritional supplements. Drug Interaction Facts contains
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




comprehensive information on drug interaction facts; it does not include nutritional supplements.
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 c3 c3 c 3 c3 c3




NAT: NCLEX Client Needs Category: Physiological Integrity
c3 c 3 c3 c3 c3 c3 c3




TOP: NursingProcess Step: Assessment
c CON: Nutrition |Patient Education
3 c3 c3 c3 c 3 c3 c3 c3




3. Whichdrugreference contains drugmonographs that describe all drugs ina therapeutic class?
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




a. DrugFactsandComparisons c3 c3 c3




TestBank For Clayton’s Basic Pharmacology for Nurses 19th Edition c3 c3 c3 c3 c3 c3 c3 c3 c3

,TestBank For Clayton’s Basic PharmacologyforNurses 19th Edition
c3 c3 c3 c3 c3 c3 c3 c3 c3 2

b. DrugInteractionFacts c3 c3




c. Handbookon Injectable Drugs c3 c3 c3




d. Martindale—TheCompleteDrugReference c3 c3 c3




ANS: A c 3




Drug Facts and Comparisons contains drug monographs that describe all drugs in a
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




therapeuticclass.Monographsareformattedastablestoallowcomparison ofsimilar
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




products, brand names, manufacturers, cost indices, and available dosage forms Online
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




version is available.
c3 c3 c3




DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 c3 c3 c 3 c3 c3 c3




OBJ: 3 NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
c 3 c 3 c 3 c3 c3 c3 c3 c3




TOP: NursingProcess Step: Assessment CON: Safety|Patient Education |Clinical Judgment
c 3 c3 c3 c3 c 3 c3 c3 c3 c3 c3 c3




4. Whichdrugreference contains monographs about virtuallyeverysingle-entitydrugavailable in
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




the United States and describes therapeutic uses of drugs, including approved and unapproved
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




uses?
c3




a. Martindale:TheCompleteDrugReference c3 c3 c3 c3




b. AHFSDrugInformation c3 c3




c. DrugReference c3




d. DrugFactsandComparisons c3 c3 c3




ANS: B c 3




AHFS Drug Information contains monographs about virtually every single-entity drug available
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




intheUnitedStatesanddescribes therapeuticusesofdrugs, includingapproved and unapproved
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




uses.
c3




DIF: Cognitive Level: Knowledge REF: p. 4Table 1.2 c3 c3 c 3 c3 c3 c3




OBJ: 3 NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
c 3 c 3 c 3 c3 c3 c3 c3 c3




TOP: NursingProcess Step: Planning CON: Safety|Patient Education |Clinical Judgment
c 3 c3 c3 c3 c 3 c3 c3 c3 c3 c3 c3




5. Which online drug reference makes available to healthcare providers and the public a standard,
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




comprehensive, up-to-datelookupanddownloadableresourceaboutmedicines?
c3 c3 c3 c3 c3 c3 c3 c3 c3




a. AmericanDrugIndex c3 c3




b. AmericanHospitalFormulary c3 c3




c. DailyMed
d. DrugReference c3




ANS: C c 3




DailyMed makes available tohealthcareproviders and thepublic astandard,comprehensive, up- c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




to-datelook upanddownloadableresourceabout medicines. TheAmericanDrugIndexis not
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




The drug reference is not appropriate for patient use.
c3 c3 c3 c3 c3 c3 c3 c3 c3




DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 c3 c3 c 3 c3 c3 c3 c3 OBJ:3 c3




NAT: NCLEX Client Needs Category: Physiological Integrity
c3 c 3 c3 c3 c3 c3 c3




TOP: NursingProcessStep: Implementation
c 3 c3 c3 c3




CON: Safety|PatientEducation |ClinicalJudgment
c 3 c3 c3 c3 c3 c3 c3




6. Whichlegislation authorizes theFDA to determinethesafetyof adrugbeforeits marketing?
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




a. FederalFood,Drug,and CosmeticAct(1938) c3 c3 c3 c3 c3 c3




b. DurhamHumphreyAmendment (1952) c3 c3 c3




TestBank For Clayton’s Basic Pharmacology for Nurses 19th Edition c3 c3 c3 c3 c3 c3 c3 c3 c3 c 3

,TestBank For Clayton’s Basic PharmacologyforNurses 19th Edition
c3 c3 c3 c3 c3 c3 c3 c3 c3 3

c. ControlledSubstancesAct(1970) c3 c3 c3




d. KefauverHarrisDrugAmendment(1962) c3 c3 c3 c3




ANS: A c 3




The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




safely without medical supervision and restricts their sale to prescription by a licensed
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




practitioner.The ControlledSubstancesActaddressesonlycontrolledsubstances and their
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




categorization. The Kefauver Harris Drug Amendment ensures drug efficacyand greater drug
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




before marketing them.
c3 c3 c3




DIF: Cognitive Level: Knowledge REF: p. 5Table l.3 c3 c3 c 3 c3 c3 c3




OBJ: c 3 5 NAT: NCLEX Client NeedsCategory: Physiological Integrity c3 c3 c3 c3 c3 c3




TOP:
c3 c Nursing Process Step: Assessment
3 c3 c3 c3




CON: c Safety|Patient Education|Evidence |Health Care Law
3 c3 c3 c3 c3 c3 c3 c3 c3 c3




7. Whichclassification doesmeperidine(Demerol)fall under?
c3 c3 c3 c3 c3 c3




a. I
b. II
c. III
d. IV
ANS: B c 3




Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




psychological and physical dependence. Schedule Idrugs havehigh potentialforabuse and no
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low to
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




moderate physical dependence or high psychological dependence. Schedule IV drugs have low
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




potential for abuse. Use may lead to limited physical or psychological dependence.
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




DIF: Cognitive Level: Knowledge REF: p. 10 OBJ:2 c3 c3 c 3 c3 c3




NAT: NCLEX Client NeedsCategory: Safe, EffectiveCare Environment
c3 c 3 c3 c3 c3 c3 c3 c3 c3




TOP: NursingProcess Step: Assessment
c CON: Patient Education |Addiction|Pain
3 c3 c3 c3 c 3 c3 c3 c3 c3 c3




8. Whichaction would theFDAtaketo expeditedrugdevelopment and approval foran outbreak of
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




smallpox?
c3




a. Listsmallpox asahealth orphandisease. c3 c3 c3 c3 c3 c3




b. Omitthepreclinical researchphase. c3 c3 c3 c3




c. Extendtheclinicalresearchphase. c3 c3 c3 c3




d. Fasttracktheinvestigationaldrug. c3 c3 c3 c3




ANS: D c 3




Once the Investigational New Drug Application has been approved, the drug can receive highest
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




priority within the agency, which is called fast tracking. A smallpox outbreak would become a
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




priority concern in the world. Orphan diseases are not researched in a priority manner. Preclinical
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




research is not omitted. Extending any phase of the research would mean alongertimeto develop a
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




vaccine.The FDAmust ensurethatall phasesof thepreclinical and clinical research phase have been
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




completed in a safe manner.
c3 c3 c3 c3 c3




DIF: Cognitive Level: Knowledge c3 c3 REF: p. 7 c 3 c 3 c3 OBJ: c 3 5




TestBank For Clayton’s Basic Pharmacology for Nurses 19th Edition c3 c3 c3 c3 c3 c3 c3 c3 c3 c 3

, TestBank For Clayton’s Basic PharmacologyforNurses 19th Edition
c3 c3 c3 c3 c3 c3 c3 c3 c3 4

NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
c3 c3 c3 c3 c3 c3 c3 c3




TOP: Nursing Process Step: Assessment
c3 c 3 c3 c3 c3




CON: HealthCareLaw|Health Care Policy|Infection |Care Coordination
c 3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




9. Whichstatement is trueabout over-the-counter(OTC) drugs? c3 c3 c3 c3 c3 c3 c3




a. Theyare not listed in theUSPNF. c3 c3 c3 c3 c3 c3 c3




b. Aprescription froma healthcareprovideris needed.
c3 c3 c3 c3 c3 c3 c3




c. Theyaresold without aprescription. c3 c3 c3 c3 c3




d. Theyare known onlybytheir brand names. c3 c3 c3 c3 c3 c3 c3




ANS: C c 3




OTC medications do not require a prescription. A variety of names, both generic and trade, canbe
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




used forindividualdrugs sold OTC. OTC drugs arelisted inthe USP NF. Prescription drugs require
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




an order by a health professional who is licensed to prescribe, such as a physician, nurse
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




practitioner, physician assistant, or dentist.
c3 c3 c3 c3 c3




DIF: Cognitive Level: Comprehension REF: p. 2 OBJ:2 c3 c3 c 3 c3 c3




NAT: NCLEX Client Needs Category: Physiological Integrity
c3 c 3 c3 c3 c3 c3 c3




TOP: NursingProcess Step: Planning c CON: PatientEducation
3 c3 c3 c3 c 3 c3




10. Whichisthemost authoritativereference formedications thatareinjected?
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




a. Martindale:TheComplete c3 c3




b. Handbookon Injectable Drugs c3 c3 c3




c. DailyMed
d. Handbookof Nonprescription Drugs c3 c3 c3




ANS: B c 3




The Handbook on Injectable Drugs is the most comprehensive reference available on the topicof
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




compatibilityofinjectabledrugs. It isacollection ofmonographs formorethan 300 injectable drugs
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




that are listed alphabetically by generic name.
c3 c3 c3 c3 c3 c3 c3




DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 c3 c3 c 3 c3 c3




NAT: NCLEX Client Needs Category: Physiological Integrity
c3 c 3 c3 c3 c3 c3 c3




TOP: NursingProcess Step: Assessmentc CON: ClinicalJudgment |Safety
3 c3 c3 c3 c 3 c3 c3 c3




11. Whichstatement istrueabout Lomotil? c3 c3 c3 c3 c3




a. Abusepotential forthis drugis low. c3 c3 c3 c3 c3 c3




b. Psychologicaldependencyislikely. c3 c3 c3




c. Thereis ahigh potential forabuse. c3 c3 c3 c3 c3 c3




d. This drugis not acontrolled substance. c3 c3 c3 c3 c3 c3




ANS: A c 3




Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




dependenceliabilitycompared with drugs inSchedule IV. Because abusepotential islowwith a
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




Schedule Vdrug, a prescription maynot be required. Psychological dependencyis not likely with a
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




Schedule V drug. Schedule V drugs are classified as controlled substances.
c3 c3 c3 c3 c3 c3 c3 c3 c3 c3 c3




DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ:2 c3 c3 c 3 c3 c3 c3 c3




NAT: NCLEX Client Needs Category: Physiological Integrity
c3 c 3 c3 c3 c3 c3 c3




TOP: NursingProcess Step: Assessmentc CON: ClinicalJudgment |Safety|Patient Education
3 c3 c3 c3 c 3 c3 c3 c3 c3 c3 c3