Updated Latest Test Bank for Berne and Levy Physiology 8th Edition Koeppen Comprehensive Physiology Study Resource with Verified Answers 2026–2027.

Berne and Levy Physiology 8th Edition
Koepp




Berne and Levy Physiology 8th Edition KoeppenTest Bank

KoeppenChapter 01: Principles of Cel Function Test Bank F




Multiple Choice

1. The subcellular structure that degrades proteins is called the:
F F F F F F F F




A. Tight junction F




B. Mitochondria
C. Lysosome
D. Plasma membrane F




E. Ribosome
ANS: C

2. An experiment is done to measure the uptake of an amino acid into a cell. The
F F F F F F F F F F F F F F F F




foll owing data are obtained:
F F F F




N




If Na+ is removed from the extracellular bathing solution, or if a drug is added
F F F F F F F F F F F F F F F that F




preve nts the cell from making adenosine triphosphate (ATP), the uptake of amino
F F F F F F F F F F F F F acid F




into th e cell is markedly reduced. According to this information, which of
F F F F F F F F F F F F F the F




followingmechan isms is probably responsible for the transport of the amino acid
F F F F F F F F F F F F into F




the cell?
F




A. Passive diffusion through the lipid bilayer F F F F F




B. Uniporter
C. Transport ATPase F




D. Na+ symporter F




E. Na+ antiporter
F




ANS: D F F




3. A membrane permeable by only Na+ separates two compartments contain
F F F F F F F F F F



ing Na2SO4,shown as follows:
F F F

, Berne and Levy Physiology 8th Edition
Koepp




Electrodes are placed in both compartments, and a voltage is applied (that of
F F F F F F F F F F F F F




compartme nt A is held at 0 mV). What voltage applied to compartment B would
F F F F F F F F F F F F F F F




resultin no net mo vement of Na+ across the membrane separating the compartments?
F F F F F F F F F F F F




A. –60 mV F




B. –30 mV F




C. 0 mVF




D. +30 mV F F




E.
+60 m F F




V ANS: EF F




4. The resting membrane potentN
F ial oRf a Ic e llGis – TV F F F F F F F F




B85.m U S N concentrations of several ions are indicat
CV. The intracellular and extracellular F F F F F F F F F F F



ed in the following table, as is the calculated
F F F F F F F F




Nernst equilibrium potential (Ei) for each of these ions:
F F F F F F F F




Ion Concentration Concentration Ei
Inside Cell F Outside Cell F



+
Na 12 mEq/L F 145 mEq/L F 66 mV
F




K+ 150 mEq/L F 4 mEq/L
F –96 mV F




Cl– 30 mEq/L F 105 mEq/L F –33 mV F




Ca++ 0.0001 mmol/dL F 1 mmol/dL
F 122 mV F




The membrane has channels for Na+, K+, Cl–
F F F F F F F




, and Ca++. The conductance of the membrane is the greatest for which ion
F F F F F F F F F F F F F




?

A. Na+
B. K+
C. Cl–
D. Ca++
ANS:
B

5. A cell contains the following membrane transporters:
F F F F F F




Na+ channelK+ channe
F F



l Na+,K+-ATPase
F

,Berne and Levy Physiology 8th Edition
Koepp
The resting membrane voltage of the cell is –80 mV, and the intracellular and
F F F F F F F F F F F F F



extracellular ion concentrations are as follows:
F F F F F




Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L F 145 mEq/L F




K+ 120 mEq/L F 4 mEq/L F




The cell is treated with a drug to inhibit the Na+,K+-
F F F F F F F F F F




ATPase. What would be the effect ofthis drug on the following parameters?
F F F F F F F F F F F




Intracellular [Na+] F Intracellular [K+] F Cell Volume F Membrane Voltage
F




A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
F




D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize

ANS: B

6. Which of the labeled proteins (shaded) is attached to the membrane
F F F F F F F F F F F




by a glycosylphosphatidylinositol (GPI) anchor?
F F F F




ANS: E


7.
A cell has channels for Na+, K+, and Cl–
F F F F F F F F




in its plasma membrane. The resting membrane potential is –
F F F F F F F F F




60 mV (cell interior negative). The intracellular and extracellular
F F F F F F F F F




concentrations for these ions, as well as the calculated Nernst potentials, are
F F F F F F F F F F F F




listed as follows: F F

, Berne and Levy Physiology 8th Edition
Koepp




Ion Intracellular F Extracellular F Ei
Concentration Concentration
Na+ 14 mEq/L F 140 mEq/L F 60 mV F




K+ 150 mEq/L F 5 mEq/L F –89 mV F




Cl– 10 mEq/L F 100 mEq/L F –60 mV F




A drug is applied to the cell that increases the permeability of the cell by Cl–
F F F F F F F F F F F F F F F




(i.e., it opens Cl–
F F F




channels). What effect will this drug have on the net movement of Cl–
F F F F F F F F F F F F



acrossthe plasma membrane? F F




A. Net Cl– movement out of the cell will be increased.
F F F F F F F F F




B. Net Cl– movement into the cell will be increased.
F
F
F F F F F F




C. There will be no change in the net movement of Cl–.
F F F F F F F F F F




ANS: C



8. Reducing the extracellular [K+] would be expected to have which of the follo wing
F F F F F F F F F F F F F F




effects on the resting membrane potential and on the excitability of ve ntricular
F F F F F F F F F F F F F




myocytes?

Membrane Potential F Excitability
A. Unchanged Unchanged
B. Hyperpolarized GDT
ecBre.aC
seO
d
C. Hyperpolarized Increased
D. Depolarized Decreased
E. Depolarized Increased

ANS: B


9. A cell is bathed in an isotonic NaCl solution that contains 5 mmol/L of
F F F F F F F F F F F F F F




glucose. The intracellular concentration of glucose is 10 mmol/L. What is the
F F F F F F F F F F F F




most likely mechanism for the transport of glucose across the plasma
F F F F F F F F F F F




membrane into this cel l? F F F F




A. Glucose uniporter F




B. Na+-glucose symporter F




C. Na+-glucose antiporter F




D. Diffusion of glucose through the lipid bilayer of the membr
F F F F F F F F F F




ane ANS: B
F F




10. A blood sample is taken from an individual whose blood osmolality is 295
F F F F F F F F F F F F F




mOs m per kilogram of water. Red blood cells from this sample are then
F F F F F F F F F F F F F F




placed in the following solutions: F F F F