NSG 6005 WEEK 3 EXAM PREPARATION PACK
2026 KEY CONCEPTS AND REVISION NOTES
◉ The elderly are at high risk of ADRs due to:
o Having greater muscle mass than younger adults, leading to higher
volume of distribution
o The extensive studies that have been conducted on drug safety in
this age group
o The blood-brain barrier being less permeable, requiring higher
doses to achieve therapeutic effect
o Age-related decrease in renal function
Answer: o Age-related decrease in renal function
◉ Which of the following factors may adversely affect a patient's
adherence to a therapeutic drug regimen?
o Complexity of the drug regimen
o Patient's perception of the potential adverse effects of the drugs
o Both A and B
o Neither A nor B
Answer: o Both A and B
,◉ The first step in the prescribing process according to the World
Health Organization is:
o Choosing the treatment
o Educating the patient about the medication
o Diagnosing the patient's problem
o Starting the treatment
Answer: o Diagnosing the patient's problem
◉ Patients with psychiatric illnesses have adherence rates to their
drug regimen between 35% and 60%. To improve adherence in this
population, prescribe drugs:
o With a longer half-life so that missed doses produce a longer taper
on the drug curve
o In oral formulations that are more easily taken
o That do not require frequent monitoring
o Combined with patient education about the need to adhere even
when symptoms are absent
Answer: o With a longer half-life so that missed doses produce a
longer taper on the drug curve
,◉ An advantage of prescribing a sublingual medication is that the
medication is:
o Absorbed rapidly
o Excreted rapidly
o Metabolized minimally
o Distributed equally
Answer: o Absorbed rapidly
◉ The time required for the amount of drug in the body to decrease
by 50% is called:
o Steady state
o Half-life
o Phase II metabolism
o Reduced bioavailability time
Answer: o Half-life
◉ A patient may develop neutropenia from using topical Silvadene
for burns. Neutropenia is:
o A cytotoxic hypersensitivity reaction
, o An immune complex hypersensitivity
o An immediate hypersensitivity reaction
o A delayed hypersensitivity reaction
Answer: o A cytotoxic hypersensitivity reaction
◉ Steady state is:
o The point on the drug concentration curve when absorption
exceeds excretion
o When the amount of drug in the body remains constant
o When the amount of drug in the body stays below the minimum
toxic concentration (MTC)
o All of the above
Answer: o When the amount of drug in the body remains constant
◉ What impact does developmental variation in renal function has
on prescribing for infants and children?
a. Lower doses of renal he excreted drugs may be prescribed to
infants younger than six months
b. Higher doses of water-soluble drugs may need to be prescribed
due to increased renal excretion
c. Renal excretion rates have no impact on prescribing
2026 KEY CONCEPTS AND REVISION NOTES
◉ The elderly are at high risk of ADRs due to:
o Having greater muscle mass than younger adults, leading to higher
volume of distribution
o The extensive studies that have been conducted on drug safety in
this age group
o The blood-brain barrier being less permeable, requiring higher
doses to achieve therapeutic effect
o Age-related decrease in renal function
Answer: o Age-related decrease in renal function
◉ Which of the following factors may adversely affect a patient's
adherence to a therapeutic drug regimen?
o Complexity of the drug regimen
o Patient's perception of the potential adverse effects of the drugs
o Both A and B
o Neither A nor B
Answer: o Both A and B
,◉ The first step in the prescribing process according to the World
Health Organization is:
o Choosing the treatment
o Educating the patient about the medication
o Diagnosing the patient's problem
o Starting the treatment
Answer: o Diagnosing the patient's problem
◉ Patients with psychiatric illnesses have adherence rates to their
drug regimen between 35% and 60%. To improve adherence in this
population, prescribe drugs:
o With a longer half-life so that missed doses produce a longer taper
on the drug curve
o In oral formulations that are more easily taken
o That do not require frequent monitoring
o Combined with patient education about the need to adhere even
when symptoms are absent
Answer: o With a longer half-life so that missed doses produce a
longer taper on the drug curve
,◉ An advantage of prescribing a sublingual medication is that the
medication is:
o Absorbed rapidly
o Excreted rapidly
o Metabolized minimally
o Distributed equally
Answer: o Absorbed rapidly
◉ The time required for the amount of drug in the body to decrease
by 50% is called:
o Steady state
o Half-life
o Phase II metabolism
o Reduced bioavailability time
Answer: o Half-life
◉ A patient may develop neutropenia from using topical Silvadene
for burns. Neutropenia is:
o A cytotoxic hypersensitivity reaction
, o An immune complex hypersensitivity
o An immediate hypersensitivity reaction
o A delayed hypersensitivity reaction
Answer: o A cytotoxic hypersensitivity reaction
◉ Steady state is:
o The point on the drug concentration curve when absorption
exceeds excretion
o When the amount of drug in the body remains constant
o When the amount of drug in the body stays below the minimum
toxic concentration (MTC)
o All of the above
Answer: o When the amount of drug in the body remains constant
◉ What impact does developmental variation in renal function has
on prescribing for infants and children?
a. Lower doses of renal he excreted drugs may be prescribed to
infants younger than six months
b. Higher doses of water-soluble drugs may need to be prescribed
due to increased renal excretion
c. Renal excretion rates have no impact on prescribing
