NURS 5357 NEUROBIOLOGY EXAM 1
QUESTIONS & ANSWERS
What are the three major hypotheses of psychosis and their neurotransmitter networks?
- Correct Answers -Dopamine theory - hyperactive dopamine at D2 receptors in the
mesolimbic pathway
Glutamate theory - NMDA receptor hypofunction
Serotonin theory - 5HT2A receptor hyperfunction in the cortex
Briefly explain the dopamine hypothesis of the positive and negative symptoms of
schizophrenia. - Correct Answers -The dopamine hypothesis of schizophrenia consists
of:
There is too much dopamine activity in the mesolimbic dopamine pathway, which leads
to positive symptoms (such as hallucinations and delusions).
There is also too little dopamine activity in the mesocortical dopamine pathway, which
leads to negative symptoms (such as blunting of affect, poverty of speech, anhedonia,
and so on).
What pathway is responsible for regulating dopamine in the hypothalamus and affects
the release of prolactin? - Correct Answers -Tuberoinfundibular pathway
Drug-induced Parkinson's is caused by a decrease of dopamine in what pathway? -
Correct Answers -Nigrostriatal pathway
Brodmann's areas are differentiated by the: - Correct Answers -Cellular architecture
All of the following are true about the hippocampus except that it: - Correct Answers -Is
disrupted by frontal lobotomy
Which of the following statements is true about the cerebellum: - Correct Answers -Has
been implicated in autism.
Cytokines are involved with all of the following except: - Correct Answers -identifying T.
pallidum
Which of the following is a possible explanation for schizophrenia: - Correct Answers -
Excessive pruning
Possible explanations for the role of thyroid hormone in mood disorders include all of
the following except: - Correct Answers -Changes in GR's
QUESTIONS & ANSWERS
What are the three major hypotheses of psychosis and their neurotransmitter networks?
- Correct Answers -Dopamine theory - hyperactive dopamine at D2 receptors in the
mesolimbic pathway
Glutamate theory - NMDA receptor hypofunction
Serotonin theory - 5HT2A receptor hyperfunction in the cortex
Briefly explain the dopamine hypothesis of the positive and negative symptoms of
schizophrenia. - Correct Answers -The dopamine hypothesis of schizophrenia consists
of:
There is too much dopamine activity in the mesolimbic dopamine pathway, which leads
to positive symptoms (such as hallucinations and delusions).
There is also too little dopamine activity in the mesocortical dopamine pathway, which
leads to negative symptoms (such as blunting of affect, poverty of speech, anhedonia,
and so on).
What pathway is responsible for regulating dopamine in the hypothalamus and affects
the release of prolactin? - Correct Answers -Tuberoinfundibular pathway
Drug-induced Parkinson's is caused by a decrease of dopamine in what pathway? -
Correct Answers -Nigrostriatal pathway
Brodmann's areas are differentiated by the: - Correct Answers -Cellular architecture
All of the following are true about the hippocampus except that it: - Correct Answers -Is
disrupted by frontal lobotomy
Which of the following statements is true about the cerebellum: - Correct Answers -Has
been implicated in autism.
Cytokines are involved with all of the following except: - Correct Answers -identifying T.
pallidum
Which of the following is a possible explanation for schizophrenia: - Correct Answers -
Excessive pruning
Possible explanations for the role of thyroid hormone in mood disorders include all of
the following except: - Correct Answers -Changes in GR's
