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Abnormal Uterine Bleeding - ANSWER--Physiologic, pathologic, or
pharmacologic
-Disruption of endocrine function at any level of the HPOA can disrupt
normal menstrual physiology-regularity, frequency, duration, or
volume
-The most common cause is a complication of pregnancy (threatened
or incomplete abortion, ectopic pregnancy, retained products of
conception, or gestational trophoblastic disease)
-Always first exclude pregnancy or a complication of pregnancy as a
cause of the bleeding.
Abnormal uterine bleeding diagnostic testing - ANSWER--HCG
-CBC to rule out anemia
-TSH to rule out hypo/hyper thyroid
,-Prolactin for complaints of headaches, galactorrhea, or peripheral
vision changes
-Pap smear
-NAAT for chlamydia and gonorrhea
-Wet mount/KOH
-Coagulation studies for history of easy bleeding/bruising, or
unexplained menorrhagia (excessive bleeding)
-Serum progesterone to confirm ovulation
Abnormal uterine bleeding non-structural abnormalities - ANSWER--
COEIN: coagulopathy, ovulatory dysfunction [most common cause of
AUB], endometrial, iatrogenic, not yet classified
Abnormal uterine bleeding structural abnormalities - ANSWER--PALM:
polyps, adenomyosis, leiomyoma, malignancy/ hyperplasia
Abnormal uterine bleeding treatment - ANSWER--Focus on
normalizing bleeding
-Correct anemia if needed
-Prevent cancer
-Restore quality of life
-Treatment depends on the cause and includes contraceptives, GnRHs,
NSAIDs, and antifibrinolytics
-Non-pharm interventions: endometrial ablation, thermal
endometrium destruction, uterine artery embolization, hysterectomy
ACOG PMS dx criteria - ANSWER--1 affective + 1 somatic symptom
, -Symptoms occur during the 5 days prior to menstrual flow
-Symptom relief within 4 days of menses
-Symptoms do not return until luteal phase (day 13 or after)
-Symptoms for 3 or more cycles
-Other conditions ruled out
-Reported negative impact on social or economic function
Adolescent recommended vaccines - ANSWER--Tdap (age 11), HPV
(boys and girls), Hep A if not previously given, and meningococcal
Amenorrhea classifications - ANSWER--Disorders of the genital
outflow tract
-Disorders of the ovary (most common cause, test estrogen levels)
-Disorders of the anterior pituitary
-Disorders of the hypothalamus or central nervous system
Amenorrhea: Etiology - ANSWER--Most common causes: pregnancy,
hypothalamic amenorrhea, and PCOS
-Primary amenorrhea: the failure to begin menses by age 16
-Secondary amenorrhea: 3 months without menses once menses has
been established
-Causes: anatomic defects, ovarian failure, chronic anovulation,
anterior pituitary disorders, CNS disorders
Anticipatory guidance - ANSWER--Expected growth and development
of their children