Page 1 of 124
BPK 105 Midterm Exam 2025/26 – 50
Human Biology Questions with Answers
and Rationales | Complete Study Guide
Intro: Prepare confidently for your
upcoming BPK 105: Human Biology
Midterm Exam with this comprehensive
2025/26 study guide, featuring 50
1. Which of the following represents the correct order of
structural organization in the human body, from simplest to most
complex?
A) Organ → Tissue → Cell → Organ system → Organism
B) Cell → Tissue → Organ → Organ system → Organism
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C) Tissue → Cell → Organ → Organ system → Organism
D) Organism → Organ system → Organ → Tissue → Cell
Answer: B
Rationale: Cells are the basic units of life. Similar cells form tissues,
tissues combine to form organs, organs work together in organ
systems, and all systems together make up an organism.
2. The maintenance of a stable internal environment despite
external changes is called:
A) Metabolism
B) Homeostasis
C) Anabolism
D) Catabolism
Answer: B
Rationale: Homeostasis refers to the body's ability to maintain
stable internal conditions (e.g., temperature, pH, blood glucose).
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Metabolism refers to all chemical reactions, while
anabolism/catabolism are subsets of metabolism.
3. Which feedback mechanism amplifies a change away from
the set point, often leading to a "cascade" effect?
A) Negative feedback
B) Positive feedback
C) Neutral feedback
D) Inhibitory feedback
Answer: B
Rationale: Positive feedback amplifies the initial stimulus (e.g.,
oxytocin release during childbirth intensifies contractions). Negative
feedback reverses a change to return to set point (e.g., body
temperature regulation).
4. Scenario: A patient has a fever due to infection. Their body
temperature rises above normal. Which type of feedback is the
fever itself (the rising temperature) initially driven by, and what
, Page 4 of 124
returns them to normal?
A) Positive feedback; sweating and vasodilation
B) Negative feedback; shivering and vasoconstriction
C) Positive feedback; antibiotics only
D) Negative feedback; fever itself
Answer: A
Rationale: The fever response is initially driven by pyrogens causing
a positive feedback loop (raising temperature to fight infection).
However, when the infection clears, negative feedback mechanisms
(sweating, vasodilation) lower temperature back to homeostasis.
5. The thoracic cavity is separated from the abdominopelvic
cavity by the:
A) Rib cage
B) Diaphragm
C) Mediastinum
D) Peritoneum
BPK 105 Midterm Exam 2025/26 – 50
Human Biology Questions with Answers
and Rationales | Complete Study Guide
Intro: Prepare confidently for your
upcoming BPK 105: Human Biology
Midterm Exam with this comprehensive
2025/26 study guide, featuring 50
1. Which of the following represents the correct order of
structural organization in the human body, from simplest to most
complex?
A) Organ → Tissue → Cell → Organ system → Organism
B) Cell → Tissue → Organ → Organ system → Organism
,Page 2 of 124
C) Tissue → Cell → Organ → Organ system → Organism
D) Organism → Organ system → Organ → Tissue → Cell
Answer: B
Rationale: Cells are the basic units of life. Similar cells form tissues,
tissues combine to form organs, organs work together in organ
systems, and all systems together make up an organism.
2. The maintenance of a stable internal environment despite
external changes is called:
A) Metabolism
B) Homeostasis
C) Anabolism
D) Catabolism
Answer: B
Rationale: Homeostasis refers to the body's ability to maintain
stable internal conditions (e.g., temperature, pH, blood glucose).
,Page 3 of 124
Metabolism refers to all chemical reactions, while
anabolism/catabolism are subsets of metabolism.
3. Which feedback mechanism amplifies a change away from
the set point, often leading to a "cascade" effect?
A) Negative feedback
B) Positive feedback
C) Neutral feedback
D) Inhibitory feedback
Answer: B
Rationale: Positive feedback amplifies the initial stimulus (e.g.,
oxytocin release during childbirth intensifies contractions). Negative
feedback reverses a change to return to set point (e.g., body
temperature regulation).
4. Scenario: A patient has a fever due to infection. Their body
temperature rises above normal. Which type of feedback is the
fever itself (the rising temperature) initially driven by, and what
, Page 4 of 124
returns them to normal?
A) Positive feedback; sweating and vasodilation
B) Negative feedback; shivering and vasoconstriction
C) Positive feedback; antibiotics only
D) Negative feedback; fever itself
Answer: A
Rationale: The fever response is initially driven by pyrogens causing
a positive feedback loop (raising temperature to fight infection).
However, when the infection clears, negative feedback mechanisms
(sweating, vasodilation) lower temperature back to homeostasis.
5. The thoracic cavity is separated from the abdominopelvic
cavity by the:
A) Rib cage
B) Diaphragm
C) Mediastinum
D) Peritoneum
