1807NRS EOT PRACTICE EXAM 2026
SOLVED QUESTIONS WITH FULL
EXPLANATIONS
◉action of b1 antagonist. Answer: decrease HR and GIT
◉action of b2 agonist. Answer: raise BP and HR and ↓ GIT
◉muscarinic antagonists action. Answer: bronchodilation, ↓
cognitive processes = sedation, ↓ peristalsis and gastric secretion
and tachycardia
◉muscarinic agonist action. Answer: bradycardia, hypotension,
pupil constriction, diaphoresis and bronchoconstriction
◉where are nicotinic receptors located. Answer: PNS and SNS
smooth and cardiac muscle, NMJ of skeletal muscles and CNS
◉MOA of nicotinic agonist. Answer: skeletal tremors, relaxation and
wellbeing sensations, adrenal medulla stimulation (↑HR), ↑ ANS tone
(↑NP, GI-diarrhoea)
,◉adverse effects of nicotinic receptor agonist. Answer: smoking can
cause HTN, nausea, insomnia
◉nursing care for nicotinic agonist. Answer: monitor skeletal
muscle weakenss and nicotine withdrawl symptoms
◉how do chemical mediators communicate. Answer: cell to cell
◉what are the 4 classifications of chemical mediators, how they
send signals and example for each. Answer: neurone (Ach) - synapse,
endocrine (Insulin) - through bloodstream, paracrine (Histamine) -
target cell is close by and autocrine (Cytokines) - target cell is the
same
◉where is histamine highly concentrated in the body. Answer: lungs,
skin, GI and CNS
◉role of histamine in the body. Answer: allergic and inflammatory
reactions, and gastric acid secretion
◉MOA of anti-histamine drugs. Answer: antagonise H1 receptors to
treat allergies
, ◉difference between 1st and 2nd generation anti-histamine drugs.
Answer: 1st gen crosses BBB (sedating) and 2nd only has small
amounts crossing BBB
◉S/E of anti-histamine drugs. Answer: dry mouth and drowsiness
◉MOA of H2 antagonist drugs. Answer: inhibits gastric secretion
◉what are prostoglandins synthesised from. Answer: omega 3 and 6
◉what are some effects of PGs. Answer: SM constriction,
vasodilation, aggregation of platelets, sensititses neurons to pain,
mediation of inflammation, produces fever, inhibits acid secretion in
stomach and relaxes uterine muscle
◉what does arachidonic acid produce. Answer: inflammatory
mediators
◉MOA of NSAIDs. Answer: inhibit PG by interfering with COX
enzymes
◉where are COXI found. Answer: stomach, intestines, kidneys and
platelets
SOLVED QUESTIONS WITH FULL
EXPLANATIONS
◉action of b1 antagonist. Answer: decrease HR and GIT
◉action of b2 agonist. Answer: raise BP and HR and ↓ GIT
◉muscarinic antagonists action. Answer: bronchodilation, ↓
cognitive processes = sedation, ↓ peristalsis and gastric secretion
and tachycardia
◉muscarinic agonist action. Answer: bradycardia, hypotension,
pupil constriction, diaphoresis and bronchoconstriction
◉where are nicotinic receptors located. Answer: PNS and SNS
smooth and cardiac muscle, NMJ of skeletal muscles and CNS
◉MOA of nicotinic agonist. Answer: skeletal tremors, relaxation and
wellbeing sensations, adrenal medulla stimulation (↑HR), ↑ ANS tone
(↑NP, GI-diarrhoea)
,◉adverse effects of nicotinic receptor agonist. Answer: smoking can
cause HTN, nausea, insomnia
◉nursing care for nicotinic agonist. Answer: monitor skeletal
muscle weakenss and nicotine withdrawl symptoms
◉how do chemical mediators communicate. Answer: cell to cell
◉what are the 4 classifications of chemical mediators, how they
send signals and example for each. Answer: neurone (Ach) - synapse,
endocrine (Insulin) - through bloodstream, paracrine (Histamine) -
target cell is close by and autocrine (Cytokines) - target cell is the
same
◉where is histamine highly concentrated in the body. Answer: lungs,
skin, GI and CNS
◉role of histamine in the body. Answer: allergic and inflammatory
reactions, and gastric acid secretion
◉MOA of anti-histamine drugs. Answer: antagonise H1 receptors to
treat allergies
, ◉difference between 1st and 2nd generation anti-histamine drugs.
Answer: 1st gen crosses BBB (sedating) and 2nd only has small
amounts crossing BBB
◉S/E of anti-histamine drugs. Answer: dry mouth and drowsiness
◉MOA of H2 antagonist drugs. Answer: inhibits gastric secretion
◉what are prostoglandins synthesised from. Answer: omega 3 and 6
◉what are some effects of PGs. Answer: SM constriction,
vasodilation, aggregation of platelets, sensititses neurons to pain,
mediation of inflammation, produces fever, inhibits acid secretion in
stomach and relaxes uterine muscle
◉what does arachidonic acid produce. Answer: inflammatory
mediators
◉MOA of NSAIDs. Answer: inhibit PG by interfering with COX
enzymes
◉where are COXI found. Answer: stomach, intestines, kidneys and
platelets
