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ATI ACTUAL EXAM NEWEST VERSION 2026 WITH NGN FORMAT QUESTIONs

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Comprehensive nursing medication review covering antipsychotics (fluphenazine, clozapine, haloperidol) with anticholinergic and extrapyramidal effects; antibiotics (gentamicin, ciprofloxacin, ceftriaxone) requiring monitoring for nephrotoxicity and tendon rupture; cardiovascular drugs (digoxin, nitroglycerin, hydrochlorothiazide, diltiazem) needing pulse/BP/potassium checks; anticoagulants (heparin, warfarin, enoxaparin) with bleeding risks; opioid antagonists (naloxone, flumazenil), antiepileptics (carbamazepine), and antidepressants (fluoxetine, bupropion) with serotonin/side effect profiles. Emphasis on lab monitoring (BUN, creatinine, potassium, digoxin levels), toxicity signs (U-waves, yellow vision, tinnitus), patient teaching (hydration, stool softeners, patch removal, sit upright after risedronate), and emergency responses (NMS, cholinergic crisis, anaphylaxis, hypoglycemia).

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ATI ACTUAL EXAM NEWEST VERSION
2026 WITH NGN FORMAT QUESTION
AND CORRECT DETAILED ANSWERS
WITH RATIONALES RATED AGRADE
1. A nurse is providing teaching with a client, who has schizophrenia, about strategies to minimize the
anticholinergic effects of fluphenazine. Which of the following instructions should the nurse suggest
for the client?

- >>>>>>>ANSWER: Chew sugarless gum to moisten the mouth.



2. Gentamicin

- >>>>>>>ANSWER: Gentamicin is a narrow-spectrum aminoglycoside antibiotic prescribed to treat
serious infections caused by aerobic bacilli.



3. Complications of Gentamicin

- >>>>>>>ANSWER: Gentamicin can injure cells of the proximal renal tubules. Naproxen and other
NSAIDs can cause renal insufficiency. The glomerular filtration rate of the kidneys decreases with
advanced age, making this client at increased risk for nephrotoxicity.



4. What lab values should a nurse monitor for a patient taking Gentamicin?

- >>>>>>>ANSWER: BUN, Blood creatinine, Peak and trough levels of gentamicin, Specific gravity of
urine, Urinalysis.



5. BUN

- >>>>>>>ANSWER: blood urea nitrogen.



6. Nursing actions for a client taking gentamicin

,- >>>>>>>ANSWER: Monitor intake and output. Notify the provider of low urinary output. Ensure that
the client is adequately hydrated and monitor for fluid overload. Assess for manifestations of
ototoxicity.



7. A nurse is preparing a client's medications. The nurse is responsible for gaining and maintaining
knowledge about which of the following medication information?

- >>>>>>>ANSWER: Adverse Effects, Mechanism of Action, Contraindications. (Use knowledge of the
therapeutic effect and common adverse effects of medications to compare expected outcomes with
actual findings.)



8. Total parenteral nutrition (TPN)

- >>>>>>>ANSWER: nutrient-complete solution given directly into bloodstream when person cannot eat
by mouth.



9. A nurse is preparing to complete an incident report for a medication error. What information (4
things) should the nurse include in the report?

- >>>>>>>ANSWER: Time of the incident, who was notified of the incident, actions taken following the
incident, client identification.



10. Adverse effects of oxybutynin

- >>>>>>>ANSWER: Anticholinergic effects (dry mouth, eyes), blurred vision, Hypotension, peripheral
edema, QT interval prolongation.



11. Adverse effects of fentanyl patches

- >>>>>>>ANSWER: Respiratory Depression, Hypotension, Constipation, Nausea or Vomiting.



12. Clients who use fentanyl patches will likely need to take what on a daily basis?

- >>>>>>>ANSWER: Take a stool softener on a daily basis. Constipation is an adverse effect of opioid use
and stool softeners can decrease the severity.



13. Adverse effects of haloperidol

- >>>>>>>ANSWER: extrapyramidal symptoms.

, 14. Extrapyramidal symptoms

- >>>>>>>ANSWER: involuntary fine motor tremors, rigidity, uncontrollable restlessness, dystonia,
pseudoparkinsonism, and akathisia.



15. When using dopamine to treat heart failure, what are signs to watch indicating the medication is
effective

- >>>>>>>ANSWER: Dopamine is an adrenergic that causes a receptor specificity effect, which increases
cardiac output and improves perfusion. You might notice increased urine output as well.



16. Adverse effects of Hydrochlorothiazide

- >>>>>>>ANSWER: Dizziness, vertigo, orthostatic hypotension, nausea, anorexia, vomiting, dry mouth,
diarrhea, polyuria, nocturia, muscle cramps, or spasms. (think: LOWERS BP).



17. A nurse is preparing to administer hydrochlorothiazide to a client. What actions should the nurse
take prior to administering this medication?

- >>>>>>>ANSWER: HCTZ is a thiazide diuretic administered to promote urine output and reduce blood
pressure and edema. The nurse should obtain the client's blood pressure prior to administration of the
medication.



18. What is sucralfate?

- >>>>>>>ANSWER: Forms protective coat over ulcers, causes constipation.



19. Is Zolpidem designed for long or short term use?

- >>>>>>>ANSWER: short term.



20. Zolpidem adverse effects

- >>>>>>>ANSWER: Drowsiness, headache, dizziness, complex sleep-related behavior, amnesia.



21. What is Zolpidem primarily used to treat?

- >>>>>>>ANSWER: insomnia.

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