Test Bank Lehne's Pharmacology for Nursing Care, 11th
Edition by Jacqueline Burchum, Laura Rosenthal Chapter 1-
112|Complete Guide A+
Psychopharmacology FINAL EXAM 3
Chapter 3: Drug Regulation, Development, Names, and Information
Test Bank
MULTIPLE CHOICE
1. A nurse educator is conducting a continuing education class on pharmacology. To evaluate
T T T T T T T T T T T
the learning of the nurses in the class, the nurse educator asks, ―Which drug name is a
T T T T T T T T T T T T T T T T T
generic drug name?‖ Which is the correct response? a. Acetaminophen
T T T T T T T T T
b. Tylenol
c. Cipro
d. Motrin
ANS: A T
Acetaminophen is the generic name. Tylenol, Cipro, and Motrin are all trade names.
T T T T T T T T T T T T
DIF: Cognitive Level: Comprehension
T REF: Table 3-3: The Three Types of Drug Names
T T T T T T T T T T T
TOP: Nursing Process: Diagnosis
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
2. The FDA Amendments Act (FDAAA) was passed in 2007 to address which aspect of drug
T T T T T T T T T T T T T T T
safety?
a. Allowing pharmaceutical companies to identify off-label uses of medications
T T T T T T T T T
approved for other uses T T T
b. Evaluating drug safety information that emerges after a drug has been approved and is
T T T T T T T T T T T T T T
in use T
c. Expediting the approval process of the U.S. Food and Drug Administration (FDA) so
T T T T T T T T T T T T T
that needed drugs can get to market more quickly
T T T T T T T T
d. Requiring manufacturers to notify patients before removing a drug from the market
T T T T T T T T T T T
ANS: B T
The FDAAA was passed to enable the Food and Drug Administration to continue oversight of a
T T T T T T T T T T T T T T T T
drug after granting it approval so that changes in labeling could be made as necessary and
T T T T T T T T T T T T T T T T
postmarketing risks could be tracked and identified. A provision of the FDA Modernization
T T T T T T T T T T T T T
Act (FDAMA), passed in 1997, allows drug companies to promote their products for off-label
T T T T T T T T T T T T T T
uses as long as they promise to conduct studies to support their claims. Regulations to permit
T T T T T T T T T T T T T T T T
accelerated approval of drugs for life-threatening diseases were adopted in 1992 by the FDA.
T T T T T T T T T T T T T
, Test Bank Lehne's Pharmacology for Nursing Care, 11th
Edition by Jacqueline Burchum, Laura Rosenthal Chapter 1-
112|Complete Guide A+
The requirement that drug companies notify patients 6 months before removing a drug from
T T T T T T T T T T T T T T
the market is a provision of the FDAMA.
T T T T T T T
DIF: Cognitive Level: Comprehension
T REF: Landmark Drug Legislation T T T T T T
TOP: Nursing Process: Evaluation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
3. A nursing student asks a nurse about pharmaceutical research and wants to know the purpose
T T T T T T T T T T T T T T T
of randomization in drug trials. The nurse explains that randomization is used to:
T T T T T T T T T T T T
a. ensure that differences in outcomes are the result of treatment and not differences in
T T T T T T T T T T T T T T
subjects.
b. compare the outcome caused by the treatment to the outcome caused by no treatment.
T T T T T T T T T T T T T
c. make sure that researchers are unaware of which subjects are in which group.
T T T T T T T T T T T T
d. prevent subjects from knowing which group they are in and prevent preconception
T T T T T T T T T T T T
bias.
ANS: A T
Randomization helps prevent allocation bias, which can occur when researchers place subjectsT T T T T T T T T T T T
with desired characteristics in the study group and other subjects in the control group so that
T T T T T T T T T T T T T T T T
differences in outcome are actually the result of differences in subjects and not treatment.
T T T T T T T T T T T T T
Comparing treatment outcome to no treatment outcome is the definition of a controlled study.
T T T T T T T T T T T T T T
The last two options describe the use of blinding in studies; blinding ensures that researchers
T T T T T T T T T T T T T T T
or subjects (or both) are unaware of which subjects are in which group so that preconceptions
T T T T T T T T T T T T T T T T
about benefits and risks cannot bias the results.
T T T T T T T
DIF: Cognitive Level: Comprehension
T REF: The Randomized Drug Trial T T T T T T T
TOP: Nursing Process: Implementation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
4. Someone asks a nurse about a new drug that is in preclinical testing and wants to know why it
T T T T T T T T T T T T T T T T T T
cannot be used to treat a friend‘s illness. Which statement by the nurse is correct?
T T T T T T T T T T T T T T
a. ―A drug at this stage of development can be used only in patients with serious disease.‖
T T T T T T T T T T T T T T T
b. ―At this stage of drug development, the safety and usefulness of the medication is
T T T T T T T T T T T T T
unknown.‖
c. ―Clinical trials must be completed to make sure the drug is safe to use in humans.‖
T T T T T T T T T T T T T T T
d. ―Until postmarketing surveillance data are available, the drug cannot be used.‖
T T T T T T T T T T
ANS: B T
Preclinical testing must be completed before drugs can be tested in humans. In this stage,
T T T T T T T T T T T T T T T
drugs are evaluated for toxicities, pharmacokinetic properties, and potentially useful effects.
T T T T T T T T T T T
Some drugs can be used in patients before completion of Phase III studies, but this is after
T T T T T T T T T T T T T T T T T
preclinical testing is complete. Clinical trials proceed in stages, and each stage has guidelines
T T T T T T T T T T T T T T
defining how a new drug may be used and which patients may receive it. Postmarketing
T T T T T T T T T T T T T T T
surveillance takes place after a drug is in general use. T T T T T T T T T
DIF: Cognitive Level: Comprehension
T T T
, Test Bank Lehne's Pharmacology for Nursing Care, 11th
Edition by Jacqueline Burchum, Laura Rosenthal Chapter 1-
112|Complete Guide A+
REF: Landmark Drug Legislation | Stages of Drug Development
T T T T T T T T T
TOP: Nursing Process: Implementation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
T T T T T T T T T T
5. A patient asks a nurse why drugs that have been approved by the FDA still have unknown
T T T T T T T T T T T T T T T T T
side effects. The nurse tell the patient that:
T T T T T T T
a. testing for all side effects of a medication would be prohibitively expensive.
T T T T T T T T T T T
b. patients in drug trials often are biased by their preconceptions of a drug‘s benefits.
T T T T T T T T T T T T T
c. researchers tend to conduct studies that will prove the benefits of their new drugs. T T T T T T T T T T T T T
d. subjects in drug trials do not always represent the full spectrum of possible patients.
T T T T T T T T T T T T T
ANS: D T
All drug trials are limited by a relatively small group of subjects who may not have all the
T T T T T T T T T T T T T T T T T T
characteristics of people who will be using the drug; therefore, some side effects go
T T T T T T T T T T T T T T
undetected until the drug is in use. Although drug trials are very expensive, this is only an
T T T T T T T T T T T T T T T T T
indirect reason they do not detect all side effects before approval. In theory, well-designed drug
T T T T T T T T T T T T T T T
trials, using blinded studies, minimize or eliminate subject bias. Designing studies to prove
T T T T T T T T T T T T T
desired results is unethical. T T T
DIF: Cognitive Level: Analysis
T REF: Failure to Detect All Adverse Effects
T T T T T T T T T
TOP: Nursing Process: Implementation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
6. A nurse is teaching nursing students about the use of nonproprietary names for drugs. The
T T T T T T T T T T T T T T T
nurse tells them which fact about nonproprietary names?
T T T T T T T
a. They are approved by the FDA and are easy to remember.
T T T T T T T T T T
b. They are assigned by the U.S. Adopted Names Council.
T T T T T T T T
c. They clearly identify the drug‘s pharmacological classification.
T T T T T T
d. They imply the efficacy of the drug and are less complex.
T T T T T T T T T T
ANS: B T
Nonproprietary, or generic, names are assigned by the U.S. Adopted Names Council, which
T T T T T T T T T T T T T
ensures that each drug has only one name. Trade names, or brand names, are approved by the
T T T T T T T T T T T T T T T T T
FDA and are easier to remember. Some nonproprietary names contain syllables that identify
T T T T T T T T T T T T T
the classification, although not all do. Drug names are not supposed to identify the use for the
T T T T T T T T T T T T T T T T T
drug, although some brand names do so.
T T T T T T
DIF: Cognitive Level: Comprehension REF: Drug Names: The Three Types of Drug Names TOP:
T T T T T T T T T T T T T T
Nursing Process: Diagnosis T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
T T T T T T T T T T
Chapter 4: Pharmacokinetics
T T T
Test Bank
T
MULTIPLE CHOICE T
1. A patient tells the nurse that the oral drug that has been prescribed has caused a lot of stomach
T T T T T T T T T T T T T T T T T T T
, Test Bank Lehne's Pharmacology for Nursing Care, 11th
Edition by Jacqueline Burchum, Laura Rosenthal Chapter 1-
112|Complete Guide A+
discomfort in the past. What will the nurse ask the prescriber?
T T T T T T T T T T
a. Whether a sublingual form of the medication can be given
T T T T T T T T T
b. Whether the medication can be given by a parenteral route instead
T T T T T T T T T T
c. To order an enteric-coated form of the drug
T T T T T T T
d. Whether the patient can receive a sustained-release preparation of the drug
T T T T T T T T T T
ANS: C T
Enteric-coated drugs are preparations that have been coated with a material that dissolves in
T T T T T T T T T T T T T T
the intestines, not the stomach. This coating is used either to protect the drug from stomach
T T T T T T T T T T T T T T T T
acid and pepsin or to protect the stomach from a drug that can cause gastric upset. Sublingual
T T T T T T T T T T T T T T T T T
forms often are used for drugs that undergo rapid inactivation during the first pass through the
T T T T T T T T T T T T T T T T
hepatic circulation so that the drug can be absorbed directly into the systemic circulation.
T T T T T T T T T T T T T
Parenteral routes are more costly and less safe than oral administration and should not be used
T T T T T T T T T T T T T T T T
unless necessary. A sustained-release preparation is used to release the drug into the body over
T T T T T T T T T T T T T T T
a specific period to reduce the number of daily doses required to sustain therapeutic drug
T T T T T T T T T T T T T T T
levels.
DIF: Cognitive Level: Application
T T T
REF: Comparing Oral Administration with Parenteral Administration
T T T T T T T
TOP: Nursing Process: Implementation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
2. A patient claims to get better effects with a tablet of Brand X of a drug than with a tablet of
T T T T T T T T T T T T T T T T T T T T T
Brand Y of the same drug. Both brands contain the same amount of the active ingredient.
T T T T T T T T T T T T T T T T
What does the nurse know to be most likely?
T T T T T T T T
a. Advertising by pharmaceutical companies can enhance patient expectations of one brand T T T T T T T T T T T
over another, leading to a placebo effect.
T T T T T T
b. Because the drug preparations are chemically equivalent, the effects of the two brands
T T T T T T T T T T T T T
must be identical. T T
c. Tablets can differ in composition and can have differing rates of disintegration and
T T T T T T T T T T T T
dissolution, which can alter the drug‘s effects in the body. T T T T T T T T T
d. The bioavailability of a drug is determined by the amount of the drug in each dose.
T T T T T T T T T T T T T T T
ANS: C T
Even if two brands of a drug are chemically equivalent (i.e., they have identical amounts of
T T T T T T T T T T T T T T T T
the same chemical compound), they can have different effects in the body if they differ in
T T T T T T T T T T T T T T T T
bioavailability. Tablets made by different manufacturers contain different binders and fillers,
T T T T T T T T T T T
which disintegrate and dissolve at different rates and affect the bioavailability of the drug.
T T T T T T T T T T T T T
Two brands may be chemically equivalent and still differ in bioavailability, which is not
T T T T T T T T T T T T T T
determined by the amount of drug in the dose. T T T T T T T T
DIF: Cognitive Level: Application
T T T
REF: Pharmaceutical Preparations for Oral Administration
T TOP: Nursing Process: Diagnosis T T T T T T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
Edition by Jacqueline Burchum, Laura Rosenthal Chapter 1-
112|Complete Guide A+
Psychopharmacology FINAL EXAM 3
Chapter 3: Drug Regulation, Development, Names, and Information
Test Bank
MULTIPLE CHOICE
1. A nurse educator is conducting a continuing education class on pharmacology. To evaluate
T T T T T T T T T T T
the learning of the nurses in the class, the nurse educator asks, ―Which drug name is a
T T T T T T T T T T T T T T T T T
generic drug name?‖ Which is the correct response? a. Acetaminophen
T T T T T T T T T
b. Tylenol
c. Cipro
d. Motrin
ANS: A T
Acetaminophen is the generic name. Tylenol, Cipro, and Motrin are all trade names.
T T T T T T T T T T T T
DIF: Cognitive Level: Comprehension
T REF: Table 3-3: The Three Types of Drug Names
T T T T T T T T T T T
TOP: Nursing Process: Diagnosis
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
2. The FDA Amendments Act (FDAAA) was passed in 2007 to address which aspect of drug
T T T T T T T T T T T T T T T
safety?
a. Allowing pharmaceutical companies to identify off-label uses of medications
T T T T T T T T T
approved for other uses T T T
b. Evaluating drug safety information that emerges after a drug has been approved and is
T T T T T T T T T T T T T T
in use T
c. Expediting the approval process of the U.S. Food and Drug Administration (FDA) so
T T T T T T T T T T T T T
that needed drugs can get to market more quickly
T T T T T T T T
d. Requiring manufacturers to notify patients before removing a drug from the market
T T T T T T T T T T T
ANS: B T
The FDAAA was passed to enable the Food and Drug Administration to continue oversight of a
T T T T T T T T T T T T T T T T
drug after granting it approval so that changes in labeling could be made as necessary and
T T T T T T T T T T T T T T T T
postmarketing risks could be tracked and identified. A provision of the FDA Modernization
T T T T T T T T T T T T T
Act (FDAMA), passed in 1997, allows drug companies to promote their products for off-label
T T T T T T T T T T T T T T
uses as long as they promise to conduct studies to support their claims. Regulations to permit
T T T T T T T T T T T T T T T T
accelerated approval of drugs for life-threatening diseases were adopted in 1992 by the FDA.
T T T T T T T T T T T T T
, Test Bank Lehne's Pharmacology for Nursing Care, 11th
Edition by Jacqueline Burchum, Laura Rosenthal Chapter 1-
112|Complete Guide A+
The requirement that drug companies notify patients 6 months before removing a drug from
T T T T T T T T T T T T T T
the market is a provision of the FDAMA.
T T T T T T T
DIF: Cognitive Level: Comprehension
T REF: Landmark Drug Legislation T T T T T T
TOP: Nursing Process: Evaluation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
3. A nursing student asks a nurse about pharmaceutical research and wants to know the purpose
T T T T T T T T T T T T T T T
of randomization in drug trials. The nurse explains that randomization is used to:
T T T T T T T T T T T T
a. ensure that differences in outcomes are the result of treatment and not differences in
T T T T T T T T T T T T T T
subjects.
b. compare the outcome caused by the treatment to the outcome caused by no treatment.
T T T T T T T T T T T T T
c. make sure that researchers are unaware of which subjects are in which group.
T T T T T T T T T T T T
d. prevent subjects from knowing which group they are in and prevent preconception
T T T T T T T T T T T T
bias.
ANS: A T
Randomization helps prevent allocation bias, which can occur when researchers place subjectsT T T T T T T T T T T T
with desired characteristics in the study group and other subjects in the control group so that
T T T T T T T T T T T T T T T T
differences in outcome are actually the result of differences in subjects and not treatment.
T T T T T T T T T T T T T
Comparing treatment outcome to no treatment outcome is the definition of a controlled study.
T T T T T T T T T T T T T T
The last two options describe the use of blinding in studies; blinding ensures that researchers
T T T T T T T T T T T T T T T
or subjects (or both) are unaware of which subjects are in which group so that preconceptions
T T T T T T T T T T T T T T T T
about benefits and risks cannot bias the results.
T T T T T T T
DIF: Cognitive Level: Comprehension
T REF: The Randomized Drug Trial T T T T T T T
TOP: Nursing Process: Implementation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
4. Someone asks a nurse about a new drug that is in preclinical testing and wants to know why it
T T T T T T T T T T T T T T T T T T
cannot be used to treat a friend‘s illness. Which statement by the nurse is correct?
T T T T T T T T T T T T T T
a. ―A drug at this stage of development can be used only in patients with serious disease.‖
T T T T T T T T T T T T T T T
b. ―At this stage of drug development, the safety and usefulness of the medication is
T T T T T T T T T T T T T
unknown.‖
c. ―Clinical trials must be completed to make sure the drug is safe to use in humans.‖
T T T T T T T T T T T T T T T
d. ―Until postmarketing surveillance data are available, the drug cannot be used.‖
T T T T T T T T T T
ANS: B T
Preclinical testing must be completed before drugs can be tested in humans. In this stage,
T T T T T T T T T T T T T T T
drugs are evaluated for toxicities, pharmacokinetic properties, and potentially useful effects.
T T T T T T T T T T T
Some drugs can be used in patients before completion of Phase III studies, but this is after
T T T T T T T T T T T T T T T T T
preclinical testing is complete. Clinical trials proceed in stages, and each stage has guidelines
T T T T T T T T T T T T T T
defining how a new drug may be used and which patients may receive it. Postmarketing
T T T T T T T T T T T T T T T
surveillance takes place after a drug is in general use. T T T T T T T T T
DIF: Cognitive Level: Comprehension
T T T
, Test Bank Lehne's Pharmacology for Nursing Care, 11th
Edition by Jacqueline Burchum, Laura Rosenthal Chapter 1-
112|Complete Guide A+
REF: Landmark Drug Legislation | Stages of Drug Development
T T T T T T T T T
TOP: Nursing Process: Implementation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
T T T T T T T T T T
5. A patient asks a nurse why drugs that have been approved by the FDA still have unknown
T T T T T T T T T T T T T T T T T
side effects. The nurse tell the patient that:
T T T T T T T
a. testing for all side effects of a medication would be prohibitively expensive.
T T T T T T T T T T T
b. patients in drug trials often are biased by their preconceptions of a drug‘s benefits.
T T T T T T T T T T T T T
c. researchers tend to conduct studies that will prove the benefits of their new drugs. T T T T T T T T T T T T T
d. subjects in drug trials do not always represent the full spectrum of possible patients.
T T T T T T T T T T T T T
ANS: D T
All drug trials are limited by a relatively small group of subjects who may not have all the
T T T T T T T T T T T T T T T T T T
characteristics of people who will be using the drug; therefore, some side effects go
T T T T T T T T T T T T T T
undetected until the drug is in use. Although drug trials are very expensive, this is only an
T T T T T T T T T T T T T T T T T
indirect reason they do not detect all side effects before approval. In theory, well-designed drug
T T T T T T T T T T T T T T T
trials, using blinded studies, minimize or eliminate subject bias. Designing studies to prove
T T T T T T T T T T T T T
desired results is unethical. T T T
DIF: Cognitive Level: Analysis
T REF: Failure to Detect All Adverse Effects
T T T T T T T T T
TOP: Nursing Process: Implementation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
6. A nurse is teaching nursing students about the use of nonproprietary names for drugs. The
T T T T T T T T T T T T T T T
nurse tells them which fact about nonproprietary names?
T T T T T T T
a. They are approved by the FDA and are easy to remember.
T T T T T T T T T T
b. They are assigned by the U.S. Adopted Names Council.
T T T T T T T T
c. They clearly identify the drug‘s pharmacological classification.
T T T T T T
d. They imply the efficacy of the drug and are less complex.
T T T T T T T T T T
ANS: B T
Nonproprietary, or generic, names are assigned by the U.S. Adopted Names Council, which
T T T T T T T T T T T T T
ensures that each drug has only one name. Trade names, or brand names, are approved by the
T T T T T T T T T T T T T T T T T
FDA and are easier to remember. Some nonproprietary names contain syllables that identify
T T T T T T T T T T T T T
the classification, although not all do. Drug names are not supposed to identify the use for the
T T T T T T T T T T T T T T T T T
drug, although some brand names do so.
T T T T T T
DIF: Cognitive Level: Comprehension REF: Drug Names: The Three Types of Drug Names TOP:
T T T T T T T T T T T T T T
Nursing Process: Diagnosis T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
T T T T T T T T T T
Chapter 4: Pharmacokinetics
T T T
Test Bank
T
MULTIPLE CHOICE T
1. A patient tells the nurse that the oral drug that has been prescribed has caused a lot of stomach
T T T T T T T T T T T T T T T T T T T
, Test Bank Lehne's Pharmacology for Nursing Care, 11th
Edition by Jacqueline Burchum, Laura Rosenthal Chapter 1-
112|Complete Guide A+
discomfort in the past. What will the nurse ask the prescriber?
T T T T T T T T T T
a. Whether a sublingual form of the medication can be given
T T T T T T T T T
b. Whether the medication can be given by a parenteral route instead
T T T T T T T T T T
c. To order an enteric-coated form of the drug
T T T T T T T
d. Whether the patient can receive a sustained-release preparation of the drug
T T T T T T T T T T
ANS: C T
Enteric-coated drugs are preparations that have been coated with a material that dissolves in
T T T T T T T T T T T T T T
the intestines, not the stomach. This coating is used either to protect the drug from stomach
T T T T T T T T T T T T T T T T
acid and pepsin or to protect the stomach from a drug that can cause gastric upset. Sublingual
T T T T T T T T T T T T T T T T T
forms often are used for drugs that undergo rapid inactivation during the first pass through the
T T T T T T T T T T T T T T T T
hepatic circulation so that the drug can be absorbed directly into the systemic circulation.
T T T T T T T T T T T T T
Parenteral routes are more costly and less safe than oral administration and should not be used
T T T T T T T T T T T T T T T T
unless necessary. A sustained-release preparation is used to release the drug into the body over
T T T T T T T T T T T T T T T
a specific period to reduce the number of daily doses required to sustain therapeutic drug
T T T T T T T T T T T T T T T
levels.
DIF: Cognitive Level: Application
T T T
REF: Comparing Oral Administration with Parenteral Administration
T T T T T T T
TOP: Nursing Process: Implementation
T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
T T T T T T T T T T
2. A patient claims to get better effects with a tablet of Brand X of a drug than with a tablet of
T T T T T T T T T T T T T T T T T T T T T
Brand Y of the same drug. Both brands contain the same amount of the active ingredient.
T T T T T T T T T T T T T T T T
What does the nurse know to be most likely?
T T T T T T T T
a. Advertising by pharmaceutical companies can enhance patient expectations of one brand T T T T T T T T T T T
over another, leading to a placebo effect.
T T T T T T
b. Because the drug preparations are chemically equivalent, the effects of the two brands
T T T T T T T T T T T T T
must be identical. T T
c. Tablets can differ in composition and can have differing rates of disintegration and
T T T T T T T T T T T T
dissolution, which can alter the drug‘s effects in the body. T T T T T T T T T
d. The bioavailability of a drug is determined by the amount of the drug in each dose.
T T T T T T T T T T T T T T T
ANS: C T
Even if two brands of a drug are chemically equivalent (i.e., they have identical amounts of
T T T T T T T T T T T T T T T T
the same chemical compound), they can have different effects in the body if they differ in
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bioavailability. Tablets made by different manufacturers contain different binders and fillers,
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which disintegrate and dissolve at different rates and affect the bioavailability of the drug.
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Two brands may be chemically equivalent and still differ in bioavailability, which is not
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determined by the amount of drug in the dose. T T T T T T T T
DIF: Cognitive Level: Application
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REF: Pharmaceutical Preparations for Oral Administration
T TOP: Nursing Process: Diagnosis T T T T T T T T
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
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