lOMoARcPSD| 13728229
, lOMoARcPSD| 13728229
Complete Test Bank LILLEYS Pharmacology for Canadian
Health Care Practice 4th Edition SEALOCK Chapter 1-58
Chapter 01: Nursing Practice in Canada and Drug Therapy
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice, 4th Edition
MULTIPLE CHOICE
1. Which is a judgement about a particular patient’s potential need or problem? T T T T T T T T
a. A goal T
b. An assessment T
c. Subjective data T
d. A nursing diagnosis
T T
ANS: D T
Nursing diagnosis is the phase of the nursing process during which a clinical judgement is made about how a patient responds to
T T T T T T T T T T T T T T T T T T T T T T
heath conditions and life processes or vulnerability for that response.
T T T T T T T T T
DIF: Cognitive Level: Knowledge T T
2. The patient is to receive oral furosemide (Lasix) every day; however, because the patient is unable to swallow, he cannot take
T T T T T T T T T T T T T T T T T T T T T
medication orally, as ordered. The nurse needs to contact the physician. What type of problem is this?
T T T T T T T T T T T T T T T T
a. A “right time” problem
T T T
b. A “right dose” problem
T T T
c. A “right route” problem
T T T
d. A “right medication” problem
T T T
ANS: C T
This is a “right route” problem: the nurse cannot assume the route and must clarify the route with the prescriber. This is not a “right
T T T T T T T T T T T T T T T T T T T T T T T T T
time” problem because the ordered frequency has not changed. This is not a “right dose” problem because the dose is not related to an
T T T T T T T T T T T T T T T T T T T T T T T T
inability to swallow. This is not a “right medication” problem because the medication ordered will not change, just the route.
T T T T T T T T T T T T T T T T T T T
DIF: Cognitive Level: Application T T
3. The nurse has been monitoring the patient’s progress on his new drug regimen since the first dose and has been documenting signs of
T T T T T T T T T T T T T T T T T T T T T T T
possible adverse effects. What nursing process phase is the nurse practising?
T T T T T T T T T T
a. Planning
b. Evaluation
c. Implementation
d. Nursing diagnosis T
ANS: B T
Monitoring the patient’s progress is part of the evaluation phase. Planning, implementation, and nursing diagnosis are not illustrated
T T T T T T T T T T T T T T T T T T
by this example.
T T
DIF: Cognitive Level: Application T T
4. The nurse is caring for a patient who has been newly diagnosed with type 1 diabetes mellitus. Which statement best illustrates an
T T T T T T T T T T T T T T T T T T T T T T
outcome criterion for this patient?T T T T
a. The patient will follow instructions.
T T T T
b. The patient will not experience complications.
T T T T T
c. The patient adheres to the new insulin treatment regimen.
T T T T T T T T
d. The patient demonstrates safe insulin self-administration technique.
T T T T T T
ANS: D T
Having the patient demonstrate safe insulin self-administration technique is a specific and measurable outcome criterion. Following
T T T T T T T T T T T T T T T T
instructions and avoiding complications are not specific criteria. Adherence to the new insulin treatment regimen is not objective
T T T T T T T T T T T T T T T T T T
and would be difficult to measure.
T T T T T
DIF: Cognitive Level: Application T T
5. Which activity best reflects the implementation phase of the nursing process for the patient who is newly diagnosed with type 1
T T T T T T T T T T T T T T T T T T T T T
diabetes mellitus? T
a. Providing education regarding self-injection technique T T T T
b. Setting goals and outcome criteria with the patient’s input
T T T T T T T T
c. Recording a history of over-the-counter medications used at homeT T T T T T T T
d. Formulating nursing diagnoses regarding knowledge deficits related to the new T T T T T T T T T T
treatment regimen T
ANS: A T
Education is an intervention that occurs during the implementation phase. Setting goals and outcome criteria reflects the planning
T T T T T T T T T T T T T T T T T T
phase. Recording a drug history reflects the assessment phase. Formulating nursing diagnoses regarding a knowledge deficit
T T T T T T T T T T T T T T T T
reflects analysis of data as part of the planning phase.
T T T T T T T T T
DIF: Cognitive Level: Analysis T T
1
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6. The nurse is working during a very busy night shift, and the health care provider has just given the nurse a medication order over the
T T T T T T T T T T T T T T T T T T T T T T T T T
telephone, but the nurse does not recall the route. What is the best way for the nurse to avoid medication errors?
T T T T T T T T T T T T T T T T T T T T
a. Recopy the order neatly on the order sheet, with the most common route indicated
T T T T T T T T T T T T T
b. Consult with the pharmacist for clarification about the most common route
T T T T T T T T T T
c. Call the health care provider to clarify the route of administration
T T T T T T T T T T
d. Withhold the drug until the health care provider visits the patient T T T T T T T T T T
ANS: C T
If a medication order does not include the route, the nurse must ask the health care provider to clarify it. Never assume the route of
T T T T T T T T T T T T T T T T T T T T T T T T T
administration.
DIF: Cognitive Level: Application | Cognitive Level: Analysis T T T T T T
7. Which constitutes the traditional Five Rights of medication administration?
T T T T T T T T
a. Right drug, right route, right dose, right time, and right patient
T T T T T T T T T T
b. Right drug, the right effect, the right route, the right time, and the right patient
T T T T T T T T T T T T T T
c. Right patient, right strength, right diagnosis, right drug, and right route
T T T T T T T T T T
d. Right patient, right diagnosis, right drug, right route, and right time
T T T T T T T T T T
ANS: A T
The traditional Five Rights of medication administration were considered to be Right drug, Right route, Right dose, Right time, and
T T T T T T T T T T T T T T T T T T T T
Right patient. Right effect, right strength, and right diagnosis are not part of the traditional Five Rights.
T T T T T T T T T T T T T T T T
DIF: Cognitive Level: Comprehension T T
8. What correctly describes the nursing process?
T T T T T
a. Diagnosing, planning, assessing, implementing, and finally evaluating T T T T T T
b. Assessing, then diagnosing, implementing, and ending with evaluating T T T T T T T
c. A linear direction that begins with assessing and continues through diagnosing,
T T T T T T T T T T T
planning, and finally implementing T T T
d. An ongoing process that begins with assessing and continues with diagnosing,
T T T T T T T T T T T
planning, implementing, and evaluating T T T
ANS: D T
The nursing process is an ongoing, flexible, adaptable, and adjustable five-step process that begins with assessing and continues
T T T T T T T T T T T T T T T T T T
through diagnosing, planning, implementing, and finally evaluating, which may then lead back to any of the other phases.
T T T T T T T T T T T T T T T T T
DIF: Cognitive Level: Application T T
9. When the nurse is considering the timing of a drug dose, which is most important to assess?
T T T T T T T T T T T T T T T T
a. The patient’s identification T T
b. The patient’s weight T T
c. The patient’s last meal T T T
d. Any drug or food allergies T T T T
ANS: C T
The pharmacokinetic and pharmacodynamic properties of the drug need to be assessed with regard to any drug–food interactions or
T T T T T T T T T T T T T T T T T T T
compatibility issues. The patient’s identification, weight, and drug or food allergies are not affected by the drug’s timing.
T T T T T T T T T T T T T T T T T
DIF: Cognitive Level: Application T T
10. The nurse is writing nursing diagnoses for a plan of care. Which reflects the correct format for her nursing diagnosis?
T T T T T T T T T T T T T T T T T T T
a. Anxiety
b. Anxiety related to new drug therapy T T T T T
c. Anxietyrelated to anxious feelings about drug therapy, as evidenced byT T T T T T T T T T T
statements such as “I’m upset about having to give myself shots” T T T T T T T T T T
d. Anxiety related to new drug therapy, as evidenced by statements such as “I’m
T T T T T T T T T T T T T
upset about having to give myself shots”
T T T T T T
ANS: D T
Formulation of nursing diagnoses is usually a three-step process. The only complete answer is “Anxiety related to new drug
T T T T T T T T T T T T T T T T T T T
therapy, as evidenced by statements such as ‘I’m upset about having to give myself shots.’” The answer “Anxiety” is missing the
T T T T T T T T T T T T T T T T T T T T T
“related to” and “as evidenced by” portions. The answer “Anxiety related to new drug therapy” is missing the “as evidenced by”
T T T T T T T T T T T T T T T T T T T T T
portion of defining characteristics. The “related to” section in “Anxiety related to anxious feelings about drug therapy, as evidenced by
T T T T T T T T T T T T T T T T T T T T
statements such as ‘I’m upset about having to give myself shots’” is simply a restatement of the problem “anxiety,” not a separate
T T T T T T T T T T T T T T T T T T T T T T
factor related to the response.
T T T T
DIF: Cognitive Level: Analysis T T
OTHER
1. Place the phases of the nursing process in the correct order, starting with the first phase.
T T T T T T T T T T T T T T T
a. Planning
b. Evaluation
c. Assessment
d. Implementation
e. Diagnosing
ANS:
C, E, A, D, B
T T T T
DIF: Cognitive Level: Analysis T T
2
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Chapter 02: Pharmacological Principles
T T T
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice, 4th Edition
T T T T T T T T T
MULTIPLE CHOICE T
1. A patient is receiving two different drugs, which, at their current dose forms and dosages, are both absorbed into the circulation in
T T T T T T T T T T T T T T T T T T T T T T
identical amounts. Which term best denotes that the drugs have the same absorption rates?
T T T T T T T T T T T T T
a. Equivalent
b. Synergistic
c. Compatible
d. Bioequivalent
ANS: D T
Two drugs absorbed into the circulation at the same amount (in specific dosage forms) have the same bioavailability; thus, they are
T T T T T T T T T T T T T T T T T T T T T
bioequivalent. “Equivalent” is incorrect because the term “bioavailability” is used to express the extent of drug absorption.
T T T T T T T T T T T T T T T T
“Synergistic” is incorrect because this term refers to two drugs given together whose resulting effect is greater than the sum of the
T T T T T T T T T T T T T T T T T T T T T T
effects of each drug given alone. “Compatible” is incorrect because this term is a general term used to indicate that two substances do
T T T T T T T T T T T T T T T T T T T T T T T
not have a chemical reaction when mixed (or given, in the case of drugs) together.
T T T T T T T T T T T T T T
DIF: T T Cognitive Level: Comprehension T T
2. A patient is receiving medication via intravenous injection. Which information should the nurse provide for patient education?
T T T T T T T T T T T T T T T T
a. The medication will cause fewer adverse effects when given intravenously.
T T T T T T T T T
b. The medication will be absorbed slowly into the tissues over time.
T T T T T T T T T T
c. The medication’s action will begin faster when given intravenously.
T T T T T T T T
d. Most of the drug is inactivated by the liver before it reaches the target area.
T T T T T T T T T T T T T T
ANS: C T
Intravenous injections are the fastest route of absorption. The intravenous route does not affect the number of adverse effects, the
T T T T T T T T T T T T T T T T T T T T
intravenous route is not a slow route of absorption, and the intravenous route does not cause inactivation of the drug by the liver
T T T T T T T T T T T T T T T T T T T T T T T
before it reaches the target area.
T T T T T
DIF: T T Cognitive Level: Comprehension T T
3. Which is true regarding parenteral drugs?
T T T T T
a. They bypass the first-pass effect. T T T T
b. They decrease blood flow to the stomach. T T T T T T
c. They are altered by the presence of food in the stomach.
T T T T T T T T T T
d. They exert their effects while circulating in the bloodstream.
T T T T T T T T
ANS: A T
Drugs given by the parenteral route bypass the first-pass effect, but they still must be absorbed into cells and tissues before they can
T T T T T T T T T T T T T T T T T T T T T T T
exert their effects. Enteral drugs (drugs taken orally), not parenteral drugs, decrease blood flow to the stomach and are altered by the
T T T T T T T T T T T T T T T T T T T T T T
presence of food in the stomach. Parenteral drugs must be absorbed into cells and tissues from the circulation before they can exert
T T T T T T T T T T T T T T T T T T T T T T
their effects; they do not exert their effects while circulating in the bloodstream.
T T T T T T T T T T T T
DIF: T T Cognitive Level: Analysis T T
4. A drug’s half-life is best defined as
T T T T T T
a. The time it takes for the drug to elicit half its therapeutic response.
T T T T T T T T T T T T
b. The time it takes one-half of the original amount of a drug to reach the target
T T T T T T T T T T T T T T T T
cells.
c. The time it takes one-half of the original amount of a drug to be removed from the
T T T T T T T T T T T T T T T T T
body.
d. The time it takes one-half of the original amount of a drug to be absorbed into the
T T T T T T T T T T T T T T T T T
circulation.
ANS: C T
A drug’s half-life is the time it takes for one-half of the original amount of a drug to be removed from the body. It is a measure of the
T T T T T T T T T T T T T T T T T T T T T T T T T T T T T
rate at which drugs are removed from the body. Answers A, B, and D are not correct definitions of a drug’s half-life.
T T T T T T T T T T T T T T T T T T T T T
DIF: T T Cognitive Level: Comprehension T T
5. The term “duration of action” is best defined as
T T T T T T T T
a. The time it takes for the drug to elicit a therapeutic response.
T T T T T T T T T T T
b. The time it takes a drug to reach its maximum therapeutic response.
T T T T T T T T T T T
c. The length of time it takes to remove a drug from circulation.
T T T T T T T T T T T
d. The time during which drug concentration is sufficient to elicit a therapeutic
T T T T T T T T T T T T
response.
ANS: D T
Duration of action is the time during which drug concentration is sufficient to elicit a therapeutic response. The time it takes for a
T T T T T T T T T T T T T T T T T T T T T T T
drug to elicit a therapeutic response is the drug’s “onset of action.” The time it takes a drug to reach its maximum therapeutic
T T T T T T T T T T T T T T T T T T T T T T T
response is a drug’s “peak effect.” “The length of time it takes to remove a drug from circulation” defines a drug’s elimination and
T T T T T T T T T T T T T T T T T T T T T T T
does not correctly define a drug’s duration of action.
T T T T T T T T
DIF: T T Cognitive Level: Comprehension T T
1
, lOMoARcPSD| 13728229
Complete Test Bank LILLEYS Pharmacology for Canadian
Health Care Practice 4th Edition SEALOCK Chapter 1-58
Chapter 01: Nursing Practice in Canada and Drug Therapy
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice, 4th Edition
MULTIPLE CHOICE
1. Which is a judgement about a particular patient’s potential need or problem? T T T T T T T T
a. A goal T
b. An assessment T
c. Subjective data T
d. A nursing diagnosis
T T
ANS: D T
Nursing diagnosis is the phase of the nursing process during which a clinical judgement is made about how a patient responds to
T T T T T T T T T T T T T T T T T T T T T T
heath conditions and life processes or vulnerability for that response.
T T T T T T T T T
DIF: Cognitive Level: Knowledge T T
2. The patient is to receive oral furosemide (Lasix) every day; however, because the patient is unable to swallow, he cannot take
T T T T T T T T T T T T T T T T T T T T T
medication orally, as ordered. The nurse needs to contact the physician. What type of problem is this?
T T T T T T T T T T T T T T T T
a. A “right time” problem
T T T
b. A “right dose” problem
T T T
c. A “right route” problem
T T T
d. A “right medication” problem
T T T
ANS: C T
This is a “right route” problem: the nurse cannot assume the route and must clarify the route with the prescriber. This is not a “right
T T T T T T T T T T T T T T T T T T T T T T T T T
time” problem because the ordered frequency has not changed. This is not a “right dose” problem because the dose is not related to an
T T T T T T T T T T T T T T T T T T T T T T T T
inability to swallow. This is not a “right medication” problem because the medication ordered will not change, just the route.
T T T T T T T T T T T T T T T T T T T
DIF: Cognitive Level: Application T T
3. The nurse has been monitoring the patient’s progress on his new drug regimen since the first dose and has been documenting signs of
T T T T T T T T T T T T T T T T T T T T T T T
possible adverse effects. What nursing process phase is the nurse practising?
T T T T T T T T T T
a. Planning
b. Evaluation
c. Implementation
d. Nursing diagnosis T
ANS: B T
Monitoring the patient’s progress is part of the evaluation phase. Planning, implementation, and nursing diagnosis are not illustrated
T T T T T T T T T T T T T T T T T T
by this example.
T T
DIF: Cognitive Level: Application T T
4. The nurse is caring for a patient who has been newly diagnosed with type 1 diabetes mellitus. Which statement best illustrates an
T T T T T T T T T T T T T T T T T T T T T T
outcome criterion for this patient?T T T T
a. The patient will follow instructions.
T T T T
b. The patient will not experience complications.
T T T T T
c. The patient adheres to the new insulin treatment regimen.
T T T T T T T T
d. The patient demonstrates safe insulin self-administration technique.
T T T T T T
ANS: D T
Having the patient demonstrate safe insulin self-administration technique is a specific and measurable outcome criterion. Following
T T T T T T T T T T T T T T T T
instructions and avoiding complications are not specific criteria. Adherence to the new insulin treatment regimen is not objective
T T T T T T T T T T T T T T T T T T
and would be difficult to measure.
T T T T T
DIF: Cognitive Level: Application T T
5. Which activity best reflects the implementation phase of the nursing process for the patient who is newly diagnosed with type 1
T T T T T T T T T T T T T T T T T T T T T
diabetes mellitus? T
a. Providing education regarding self-injection technique T T T T
b. Setting goals and outcome criteria with the patient’s input
T T T T T T T T
c. Recording a history of over-the-counter medications used at homeT T T T T T T T
d. Formulating nursing diagnoses regarding knowledge deficits related to the new T T T T T T T T T T
treatment regimen T
ANS: A T
Education is an intervention that occurs during the implementation phase. Setting goals and outcome criteria reflects the planning
T T T T T T T T T T T T T T T T T T
phase. Recording a drug history reflects the assessment phase. Formulating nursing diagnoses regarding a knowledge deficit
T T T T T T T T T T T T T T T T
reflects analysis of data as part of the planning phase.
T T T T T T T T T
DIF: Cognitive Level: Analysis T T
1
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6. The nurse is working during a very busy night shift, and the health care provider has just given the nurse a medication order over the
T T T T T T T T T T T T T T T T T T T T T T T T T
telephone, but the nurse does not recall the route. What is the best way for the nurse to avoid medication errors?
T T T T T T T T T T T T T T T T T T T T
a. Recopy the order neatly on the order sheet, with the most common route indicated
T T T T T T T T T T T T T
b. Consult with the pharmacist for clarification about the most common route
T T T T T T T T T T
c. Call the health care provider to clarify the route of administration
T T T T T T T T T T
d. Withhold the drug until the health care provider visits the patient T T T T T T T T T T
ANS: C T
If a medication order does not include the route, the nurse must ask the health care provider to clarify it. Never assume the route of
T T T T T T T T T T T T T T T T T T T T T T T T T
administration.
DIF: Cognitive Level: Application | Cognitive Level: Analysis T T T T T T
7. Which constitutes the traditional Five Rights of medication administration?
T T T T T T T T
a. Right drug, right route, right dose, right time, and right patient
T T T T T T T T T T
b. Right drug, the right effect, the right route, the right time, and the right patient
T T T T T T T T T T T T T T
c. Right patient, right strength, right diagnosis, right drug, and right route
T T T T T T T T T T
d. Right patient, right diagnosis, right drug, right route, and right time
T T T T T T T T T T
ANS: A T
The traditional Five Rights of medication administration were considered to be Right drug, Right route, Right dose, Right time, and
T T T T T T T T T T T T T T T T T T T T
Right patient. Right effect, right strength, and right diagnosis are not part of the traditional Five Rights.
T T T T T T T T T T T T T T T T
DIF: Cognitive Level: Comprehension T T
8. What correctly describes the nursing process?
T T T T T
a. Diagnosing, planning, assessing, implementing, and finally evaluating T T T T T T
b. Assessing, then diagnosing, implementing, and ending with evaluating T T T T T T T
c. A linear direction that begins with assessing and continues through diagnosing,
T T T T T T T T T T T
planning, and finally implementing T T T
d. An ongoing process that begins with assessing and continues with diagnosing,
T T T T T T T T T T T
planning, implementing, and evaluating T T T
ANS: D T
The nursing process is an ongoing, flexible, adaptable, and adjustable five-step process that begins with assessing and continues
T T T T T T T T T T T T T T T T T T
through diagnosing, planning, implementing, and finally evaluating, which may then lead back to any of the other phases.
T T T T T T T T T T T T T T T T T
DIF: Cognitive Level: Application T T
9. When the nurse is considering the timing of a drug dose, which is most important to assess?
T T T T T T T T T T T T T T T T
a. The patient’s identification T T
b. The patient’s weight T T
c. The patient’s last meal T T T
d. Any drug or food allergies T T T T
ANS: C T
The pharmacokinetic and pharmacodynamic properties of the drug need to be assessed with regard to any drug–food interactions or
T T T T T T T T T T T T T T T T T T T
compatibility issues. The patient’s identification, weight, and drug or food allergies are not affected by the drug’s timing.
T T T T T T T T T T T T T T T T T
DIF: Cognitive Level: Application T T
10. The nurse is writing nursing diagnoses for a plan of care. Which reflects the correct format for her nursing diagnosis?
T T T T T T T T T T T T T T T T T T T
a. Anxiety
b. Anxiety related to new drug therapy T T T T T
c. Anxietyrelated to anxious feelings about drug therapy, as evidenced byT T T T T T T T T T T
statements such as “I’m upset about having to give myself shots” T T T T T T T T T T
d. Anxiety related to new drug therapy, as evidenced by statements such as “I’m
T T T T T T T T T T T T T
upset about having to give myself shots”
T T T T T T
ANS: D T
Formulation of nursing diagnoses is usually a three-step process. The only complete answer is “Anxiety related to new drug
T T T T T T T T T T T T T T T T T T T
therapy, as evidenced by statements such as ‘I’m upset about having to give myself shots.’” The answer “Anxiety” is missing the
T T T T T T T T T T T T T T T T T T T T T
“related to” and “as evidenced by” portions. The answer “Anxiety related to new drug therapy” is missing the “as evidenced by”
T T T T T T T T T T T T T T T T T T T T T
portion of defining characteristics. The “related to” section in “Anxiety related to anxious feelings about drug therapy, as evidenced by
T T T T T T T T T T T T T T T T T T T T
statements such as ‘I’m upset about having to give myself shots’” is simply a restatement of the problem “anxiety,” not a separate
T T T T T T T T T T T T T T T T T T T T T T
factor related to the response.
T T T T
DIF: Cognitive Level: Analysis T T
OTHER
1. Place the phases of the nursing process in the correct order, starting with the first phase.
T T T T T T T T T T T T T T T
a. Planning
b. Evaluation
c. Assessment
d. Implementation
e. Diagnosing
ANS:
C, E, A, D, B
T T T T
DIF: Cognitive Level: Analysis T T
2
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Chapter 02: Pharmacological Principles
T T T
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice, 4th Edition
T T T T T T T T T
MULTIPLE CHOICE T
1. A patient is receiving two different drugs, which, at their current dose forms and dosages, are both absorbed into the circulation in
T T T T T T T T T T T T T T T T T T T T T T
identical amounts. Which term best denotes that the drugs have the same absorption rates?
T T T T T T T T T T T T T
a. Equivalent
b. Synergistic
c. Compatible
d. Bioequivalent
ANS: D T
Two drugs absorbed into the circulation at the same amount (in specific dosage forms) have the same bioavailability; thus, they are
T T T T T T T T T T T T T T T T T T T T T
bioequivalent. “Equivalent” is incorrect because the term “bioavailability” is used to express the extent of drug absorption.
T T T T T T T T T T T T T T T T
“Synergistic” is incorrect because this term refers to two drugs given together whose resulting effect is greater than the sum of the
T T T T T T T T T T T T T T T T T T T T T T
effects of each drug given alone. “Compatible” is incorrect because this term is a general term used to indicate that two substances do
T T T T T T T T T T T T T T T T T T T T T T T
not have a chemical reaction when mixed (or given, in the case of drugs) together.
T T T T T T T T T T T T T T
DIF: T T Cognitive Level: Comprehension T T
2. A patient is receiving medication via intravenous injection. Which information should the nurse provide for patient education?
T T T T T T T T T T T T T T T T
a. The medication will cause fewer adverse effects when given intravenously.
T T T T T T T T T
b. The medication will be absorbed slowly into the tissues over time.
T T T T T T T T T T
c. The medication’s action will begin faster when given intravenously.
T T T T T T T T
d. Most of the drug is inactivated by the liver before it reaches the target area.
T T T T T T T T T T T T T T
ANS: C T
Intravenous injections are the fastest route of absorption. The intravenous route does not affect the number of adverse effects, the
T T T T T T T T T T T T T T T T T T T T
intravenous route is not a slow route of absorption, and the intravenous route does not cause inactivation of the drug by the liver
T T T T T T T T T T T T T T T T T T T T T T T
before it reaches the target area.
T T T T T
DIF: T T Cognitive Level: Comprehension T T
3. Which is true regarding parenteral drugs?
T T T T T
a. They bypass the first-pass effect. T T T T
b. They decrease blood flow to the stomach. T T T T T T
c. They are altered by the presence of food in the stomach.
T T T T T T T T T T
d. They exert their effects while circulating in the bloodstream.
T T T T T T T T
ANS: A T
Drugs given by the parenteral route bypass the first-pass effect, but they still must be absorbed into cells and tissues before they can
T T T T T T T T T T T T T T T T T T T T T T T
exert their effects. Enteral drugs (drugs taken orally), not parenteral drugs, decrease blood flow to the stomach and are altered by the
T T T T T T T T T T T T T T T T T T T T T T
presence of food in the stomach. Parenteral drugs must be absorbed into cells and tissues from the circulation before they can exert
T T T T T T T T T T T T T T T T T T T T T T
their effects; they do not exert their effects while circulating in the bloodstream.
T T T T T T T T T T T T
DIF: T T Cognitive Level: Analysis T T
4. A drug’s half-life is best defined as
T T T T T T
a. The time it takes for the drug to elicit half its therapeutic response.
T T T T T T T T T T T T
b. The time it takes one-half of the original amount of a drug to reach the target
T T T T T T T T T T T T T T T T
cells.
c. The time it takes one-half of the original amount of a drug to be removed from the
T T T T T T T T T T T T T T T T T
body.
d. The time it takes one-half of the original amount of a drug to be absorbed into the
T T T T T T T T T T T T T T T T T
circulation.
ANS: C T
A drug’s half-life is the time it takes for one-half of the original amount of a drug to be removed from the body. It is a measure of the
T T T T T T T T T T T T T T T T T T T T T T T T T T T T T
rate at which drugs are removed from the body. Answers A, B, and D are not correct definitions of a drug’s half-life.
T T T T T T T T T T T T T T T T T T T T T
DIF: T T Cognitive Level: Comprehension T T
5. The term “duration of action” is best defined as
T T T T T T T T
a. The time it takes for the drug to elicit a therapeutic response.
T T T T T T T T T T T
b. The time it takes a drug to reach its maximum therapeutic response.
T T T T T T T T T T T
c. The length of time it takes to remove a drug from circulation.
T T T T T T T T T T T
d. The time during which drug concentration is sufficient to elicit a therapeutic
T T T T T T T T T T T T
response.
ANS: D T
Duration of action is the time during which drug concentration is sufficient to elicit a therapeutic response. The time it takes for a
T T T T T T T T T T T T T T T T T T T T T T T
drug to elicit a therapeutic response is the drug’s “onset of action.” The time it takes a drug to reach its maximum therapeutic
T T T T T T T T T T T T T T T T T T T T T T T
response is a drug’s “peak effect.” “The length of time it takes to remove a drug from circulation” defines a drug’s elimination and
T T T T T T T T T T T T T T T T T T T T T T T
does not correctly define a drug’s duration of action.
T T T T T T T T
DIF: T T Cognitive Level: Comprehension T T
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