MOLECULAR CELL BIOLOGY COMPREHENSIVE
TEST PAPER 2026 COMPLETE QUESTIONS AND
ANSWERS EXPERT VERIFIED GRADED A+
◉ Set of proteins assembled at replication fork: Answer: replisome
◉ What is the function of primase? Answer: RNA polymerase
function
◉ Which of the following is not part of the Pol III holoenzyme?
a. Pol III core
b. Beta sliding clamp
c. SSB
d. Clamp loader Answer: c. SSB
◉ The trombone model is descriptive of Answer: lagging strand
synthesis
,◉ In E.coli, ter sequences: Answer: Prevent collisions between DNA
& RNA polymerases
◉ Telomere sequences are the same in all eukaryotes. This
statement is: Answer: False
◉ The upper limit of cell division is called: Answer: Hayflick limit
◉ Telomere shrinkage occurs because:
a. DNA Polymerase requires a primer
b. Most cells do not express telomerase
c. Both a. and b. Answer: c. Both a. and b.
◉ Which of the following correctly describes a structural feature of
DNA or RNA?
a. RNA may fold into complex three-dimensional structures
necessary for its activity.
b. RNA and DNA are both usually double stranded
, c. DNA tends to fold into complex three-dimensional structures
required for its activity.
d. DNA contains a pentose sugar with a hydroxyl group in the 2'
position Answer: a. RNA may fold into complex three-dimensional
structures necessary for its activity.
◉ Which of the following techniques is most useful for evaluating a
complex mixture of proteins?
a. 2D-PAGE
b. SDS-PAGE
c. Agarose gel electrophoresis
d. ChIP-Seq
e. RT-PCR Answer: a. 2D-PAGE
◉ The Watson and Crick DNA double helix model predicted which
mode of replication? Answer: Semiconservative replication
TEST PAPER 2026 COMPLETE QUESTIONS AND
ANSWERS EXPERT VERIFIED GRADED A+
◉ Set of proteins assembled at replication fork: Answer: replisome
◉ What is the function of primase? Answer: RNA polymerase
function
◉ Which of the following is not part of the Pol III holoenzyme?
a. Pol III core
b. Beta sliding clamp
c. SSB
d. Clamp loader Answer: c. SSB
◉ The trombone model is descriptive of Answer: lagging strand
synthesis
,◉ In E.coli, ter sequences: Answer: Prevent collisions between DNA
& RNA polymerases
◉ Telomere sequences are the same in all eukaryotes. This
statement is: Answer: False
◉ The upper limit of cell division is called: Answer: Hayflick limit
◉ Telomere shrinkage occurs because:
a. DNA Polymerase requires a primer
b. Most cells do not express telomerase
c. Both a. and b. Answer: c. Both a. and b.
◉ Which of the following correctly describes a structural feature of
DNA or RNA?
a. RNA may fold into complex three-dimensional structures
necessary for its activity.
b. RNA and DNA are both usually double stranded
, c. DNA tends to fold into complex three-dimensional structures
required for its activity.
d. DNA contains a pentose sugar with a hydroxyl group in the 2'
position Answer: a. RNA may fold into complex three-dimensional
structures necessary for its activity.
◉ Which of the following techniques is most useful for evaluating a
complex mixture of proteins?
a. 2D-PAGE
b. SDS-PAGE
c. Agarose gel electrophoresis
d. ChIP-Seq
e. RT-PCR Answer: a. 2D-PAGE
◉ The Watson and Crick DNA double helix model predicted which
mode of replication? Answer: Semiconservative replication
