1 (Simple / facilitated) diffusion from high to low
concentration / down concentration gradient;
2 Small / non-polar / lipid-soluble molecules pass via phospholipids / bilayer;
OR
Large / polar / water-soluble molecules go through proteins;
3 Water moves by osmosis / from high water potential to low water potential / from less to
more negative water potential;
4 Active transport is movement from low to high
concentration / against concentration gradient;
5 Active transport / facilitated diffusion involves proteins/carriers;
6 Active transport requires energy / ATP;
7 Ref. to Na+ / glucose co-transport; -
Answer
Many different substances enter and leave a cell by crossing its cell surface membrane.
Describe how substances can cross a cell surface membrane. (5)
Quiz_________________?
1
, 1 Active site (of enzyme) has particular shape;
2 (Into which) substrate molecule fits / binds;
3 Appropriate reference linking induced fit and shape;
4 (Competitive inhibitor) has similar shape to substrate;
5 Also fits active sites;
6 Prevents substrate access;
7 (Non-competitive inhibitor) fits at site other than active site;
8 Distorting shape of active site / enzyme;
6 Prevents substrate access; (award once only)
9 Two types identified as competitive and non-competitive; -
Answer
Describe how molecular shape is important in explaining the way in which enzymes may be
affected by inhibitors. (6)
Quiz_________________?
1 each enzyme / protein has specific primary structure / amino acid sequence;
2 folds in a particular way / has particular tertiary structure giving an active site with a
unique structure;
3 shape of active site complementary to / will only fit that of substrate; maximum of three
marks for inhibition, points 5 - 8
4 inhibitor fits at site on the enzyme other than active site;
5 distorts active site;
6 so substrate will no longer fit / form enzyme-substrate complex -
Answer
Use your knowledge of protein structure to explain why enzymes are specific and may be
affected by non-competitive inhibitors. (5)
Quiz_________________?
2
, 1 Many alveoli / alveoli walls folded provide a large surface area;
2 Many capillaries provide a large surface area;
3 (So) fast diffusion;
________________________________________________
4 Alveoli or capillary walls / epithelium / lining are thin / short distance between alveoli and
blood;
5 Flattened / squamous epithelium;
6 (So) short diffusion distance / pathway;
7 (So) fast diffusion;
________________________________________________
8 Ventilation / circulation;
9 Maintains a diffusion / concentration gradient;
10 (So) fast diffusion; -
Answer
Describe and explain how the lungs are adapted to allow rapid exchange of oxygen between
air in the alveoli and blood in the capillaries around them. (5)
Quiz_________________?
1 Prokaryotic cells do not have a nucleus / have genetic material
in cytoplasm;
2 DNA in loop / ring;
3 Not associated with proteins / do not have chromosomes /
chromatin / do not divide by mitosis;
4 Smaller ribosomes;
5 No membrane-bound organelles;
6 Such as mitochondria / lysosomes / endoplasmic reticulum /
Golgi / chloroplasts;
7 Prokaryotic cells may have mesosomes;
3