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NP Pharmacology Exam : 233 Questions & Answers

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This document is a psychiatric and medical study guide for nurse practitioners (NPs) , covering key topics such as research errors (Type I/II), drug interactions (CYP450 inducers/inhibitors, Lithium, Tegretol), neuroanatomy (limbic system, amygdala, brain pathways), psychiatric scales (MMSE, Beck, PHQ-9, HAM-A, Y-BOCS), cultural competence (evil eye, Asian/Native American/Hispanic beliefs), legal/ethical issues (informed consent, HIPAA, Medicare/Medicaid), and treatment guidelines for conditions like schizophrenia, depression, OCD, fibromyalgia, and NMS. It also includes pediatric reflexes, HIV dementia, and change management models (PDSA, Appreciative Inquiry).

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NP Pharmacology Exam 2026-2027: 233 Questions &
Answers
1. What is dissemination? - .>>>>>>> ANSWER: Getting the research information out to those who need
to know it! Publication - highest level. Presenting at National Conference. Presenting at Local
Conference. Journal Club where one person reviews an article.



2. What does a 17 on MMSE mean? - .>>>>>>> ANSWER: Moderate cognitive impairment



3. What is Tegretol in the CYP450 system? - .>>>>>>> ANSWER: Inducer --> will lower dose of Lamictal
and BCP's



4. What do BCP's do to Lamictal? - .>>>>>>> ANSWER: Inducer - will lower dose of Lamictal



5. What is a Type I research error? - .>>>>>>> ANSWER: There IS a difference but you say there isn't a
difference.



6. What is a Type II research error? - .>>>>>>> ANSWER: There is NO difference but you say there is a
difference.



7. What is pseudo-dementia? - .>>>>>>> ANSWER: Cognitive impairment secondary to depression that
clears when treated in the elderly. Dementia won't improve.



8. Is it normal for a 1 month old to have a palmar grasp? - .>>>>>>> ANSWER: Yes.



9. What is a drug half-life? - .>>>>>>> ANSWER: The time it takes for 50% of a drug to be eliminated
from the body.



10. What 3 atypicals can be used with teens? - .>>>>>>> ANSWER: Zyprexa, Abilify, Seroquel - low doses



11. What is a risk of using Tramadol? - .>>>>>>> ANSWER: Serotonin Syndrome as it is very serotonergic.

,12. What is the allele seen in Asians that increases the risk of SJS? - .>>>>>>> ANSWER: HLAB-1502



13. When might you see toxic epidermal necrolysis? - .>>>>>>> ANSWER: With worsening of SJS



14. How many generations do you include for a genogram? - .>>>>>>> ANSWER: 1st degree - mother,
father, siblings. 2nd degree - grandparents & cousins. 3rd degree - (unspecified).



15. What does messenger RNA code for? - .>>>>>>> ANSWER: Amino Acids



16. What is epigenetics? - .>>>>>>> ANSWER: Factors that affect genes - environmental, smoking, stress,
etc.



17. What part of the brain is involved with OCD? - .>>>>>>> ANSWER: Basal Ganglia. Occipito-Frontal.



18. What happens to the brain during adolescence? - .>>>>>>> ANSWER: Dendritic pruning. Emotions
are controlled by amygdala. By adulthood, PFC involved as well.



19. When do males typically present with schizophrenia? - .>>>>>>> ANSWER: 10-25 yo



20. When do females typically present with schizophrenia? - .>>>>>>> ANSWER: 25-35 yo



21. What does Erythromycin do to Trileptal? - .>>>>>>> ANSWER: You will need to decrease the level
because Trileptal (inducer) and erythromycin is an inhibitor.



22. ACE Inhibitors are the drug of choice for what? - .>>>>>>> ANSWER: Heart Failure, HTN



23. What are some psychiatric side effects seen with some asthma drugs? - .>>>>>>> ANSWER:
Leukotriene receptor agonists - Singulair, Accolate, Zyflo = agitation, aggression, anxiety, hallucinations,
depression, insomnia, SI, tremor.

, 24. What should you watch for with Tegretol? - .>>>>>>> ANSWER: Agranulocytosis and Hyponatremia



25. What are the 3 CK muscle enzyme tests? - .>>>>>>> ANSWER: CKBB, CKMM, CKMB



26. Which one of the 3 muscle enzymes is related to cardiac muscle damage? - .>>>>>>> ANSWER:
CKMB



27. What is the risk of a seriously elevated CKMB? - .>>>>>>> ANSWER: Polymyositis, Rhabdo



28. What is a normal CKMB? - .>>>>>>> ANSWER: 0.3 mcg/L



29. What psychoactives does Detrol interact with? - .>>>>>>> ANSWER: Topamax, KCL, Zonegran



30. What cranial nerve are you assessing when you have the patient shrug their shoulders? - .>>>>>>>
ANSWER: CN XI - Spinal Accessory



31. What do you see in labs with HIV & Dementia? - .>>>>>>> ANSWER: CD4 <200. Viral Load is high.
<20% get it with antiretroviral treatment.



32. What is the scoring with the Beck Depression Inventory? - .>>>>>>> ANSWER: Self-Report - 0-63. 0-
13 - minimal. 14-19 - mild. 20-28 - moderate. 29-63 - severe.



33. What is sensitivity? - .>>>>>>> ANSWER: Helps rule-out disease = True Positive = Snout



34. What is specificity? - .>>>>>>> ANSWER: Helps rule-in disease = True Negative = Spin



35. What does a sed rate measure? - .>>>>>>> ANSWER: Inflammation (ESR - Erythrocyte Sedimentation
Rate) = distance in mm RBC's have descended in 1 hour.



36. What is a normal sed rate or ESR? - .>>>>>>> ANSWER: 0-22 males, 0-29 females

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