4/26/26, 8:55 AM WGU D027 pathopharm EXAM (updated 2026) Questions & Answers | With 100% Correct Answers graded A+ Guaranteed Succes…
WGU D027 pathopharm EXAM (updated 2026)
Questions & Answers | With 100% Correct Answers
graded A+ Guaranteed Success!!
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Terms in this set (141)
Mechanism of Action for loop block water reasborption in the loop of Henle of
diuretics nephron. Increases urine output
Suffix for loop -emide
ex: furosemide
cautions in using loop diuretics decreased potassium, decreased BP, ototoxicity,
nephrotoxicity
USE WITH CAUTION in those who have
auditory/renal impairments
Suffix for Thiazide Diuretics -thiazide
MOA for thiazide diuretics blood water reabsorption in distal tube of
nephron-- increases urine output
adverse drug reactions for thiazide decreases potassium, increases uric acid, increases
diuretics calcium
AVOID use in hx with gout, use cautiously with
kidney disease
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,4/26/26, 8:55 AM WGU D027 pathopharm EXAM (updated 2026) Questions & Answers | With 100% Correct Answers graded A+ Guaranteed Succes…
Contraindicator for thiazide diuretics those with sulfa allergies, contains sulfa group in
molecular structure. Also avoid in hx of gout due to
increase of uric acid
Aldosterone antagonists MOA inhibits aldosterone which results in sodium loss in
the nephron, water follows and is excreted,
potassium is retained (potassium sparing diuretic)
example of an aldosterone Spironolactone
antagonist
adverse drug reactions for high potassium, androgen blocking (blocks
aldosterone antagonists testosterone and causes estrogen effects)
beta blocker examples Propranolol (Inderal)
Metroprolol (Lopressor/Toprol XL)
Atenolol (Tenormin)
Carvedilol (Coreg)
MOA of beta blockers block adrenergic effects of Beta 1 and Beta 2
receptors (cause cholinergic effects)
result in low HR and Low BP
Contraindicators for beta blockers chronic respiratory conditions (particularly for beta
2 blockers)
HR <60 bpm
disguises hypoglycemia symptoms
What does angiotensin 2 do? angiotensin II causes vasonconstriction and
secretion of aldosterone, which results in
reabsorption of sodium/water in the nephrons
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, 4/26/26, 8:55 AM WGU D027 pathopharm EXAM (updated 2026) Questions & Answers | With 100% Correct Answers graded A+ Guaranteed Succes…
angiotensin 2 converting enzyme suffix: -pril example: lisinopril
inhibitor (ACE inhibitor) suffix and MOA: inhibits ACE from converting angiotensin 1 to
MOA angiotensin 2, therefor prevents water reabsorption
decreases cardiac workload
decreases BP
Adverse drug reactions for ACE high potassium, angioedema, dry cough
inhibitors
Angiotensin Receptor Blocker (ARBs) suffix: sartan example: losartan
suffix and MOA MOA: prevent Angiotensin2 from binding to
receptor sites, which then prevents reabsorption of
water and vasoconstriction
leads to lower BP
Adverse drug reactions of ARBS high potassium, angioedema
prefix of cardiac glycosides "dig" ex: digoxin
MOA of cardiac glycosides block Na/K pump, indirectly changes the calcium
balance, leads to powerful contraction w/ HB
does not lower blood pressure, only HR
FYIs for cardiac glycosides measure HR, hold if <60bpm
sx of digoxin toxicity: anorexia, visual disturbance,
chest palpitations
Which of the following drugs may A and B- Torsemide and HCTZ lower serum
cause hypokalemia? potassium due to increased potassium excretion in
A) torsemide the kidneys
B) hydrochlorothiazide D) When entering the circulation, digoxin binds to
C) spironolactone sodium/potassium pumps which can also decrease
D) Digoxin OR increase potassium
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WGU D027 pathopharm EXAM (updated 2026)
Questions & Answers | With 100% Correct Answers
graded A+ Guaranteed Success!!
Save Groups
Terms in this set (141)
Mechanism of Action for loop block water reasborption in the loop of Henle of
diuretics nephron. Increases urine output
Suffix for loop -emide
ex: furosemide
cautions in using loop diuretics decreased potassium, decreased BP, ototoxicity,
nephrotoxicity
USE WITH CAUTION in those who have
auditory/renal impairments
Suffix for Thiazide Diuretics -thiazide
MOA for thiazide diuretics blood water reabsorption in distal tube of
nephron-- increases urine output
adverse drug reactions for thiazide decreases potassium, increases uric acid, increases
diuretics calcium
AVOID use in hx with gout, use cautiously with
kidney disease
https://quizlet.com/1172680943/wgu-d027-pathopharm-exam-updated-2026-questions-answers-with-100-correct-answers-graded-a-guaranteed-succ… 1/30
,4/26/26, 8:55 AM WGU D027 pathopharm EXAM (updated 2026) Questions & Answers | With 100% Correct Answers graded A+ Guaranteed Succes…
Contraindicator for thiazide diuretics those with sulfa allergies, contains sulfa group in
molecular structure. Also avoid in hx of gout due to
increase of uric acid
Aldosterone antagonists MOA inhibits aldosterone which results in sodium loss in
the nephron, water follows and is excreted,
potassium is retained (potassium sparing diuretic)
example of an aldosterone Spironolactone
antagonist
adverse drug reactions for high potassium, androgen blocking (blocks
aldosterone antagonists testosterone and causes estrogen effects)
beta blocker examples Propranolol (Inderal)
Metroprolol (Lopressor/Toprol XL)
Atenolol (Tenormin)
Carvedilol (Coreg)
MOA of beta blockers block adrenergic effects of Beta 1 and Beta 2
receptors (cause cholinergic effects)
result in low HR and Low BP
Contraindicators for beta blockers chronic respiratory conditions (particularly for beta
2 blockers)
HR <60 bpm
disguises hypoglycemia symptoms
What does angiotensin 2 do? angiotensin II causes vasonconstriction and
secretion of aldosterone, which results in
reabsorption of sodium/water in the nephrons
https://quizlet.com/1172680943/wgu-d027-pathopharm-exam-updated-2026-questions-answers-with-100-correct-answers-graded-a-guaranteed-succ… 2/30
, 4/26/26, 8:55 AM WGU D027 pathopharm EXAM (updated 2026) Questions & Answers | With 100% Correct Answers graded A+ Guaranteed Succes…
angiotensin 2 converting enzyme suffix: -pril example: lisinopril
inhibitor (ACE inhibitor) suffix and MOA: inhibits ACE from converting angiotensin 1 to
MOA angiotensin 2, therefor prevents water reabsorption
decreases cardiac workload
decreases BP
Adverse drug reactions for ACE high potassium, angioedema, dry cough
inhibitors
Angiotensin Receptor Blocker (ARBs) suffix: sartan example: losartan
suffix and MOA MOA: prevent Angiotensin2 from binding to
receptor sites, which then prevents reabsorption of
water and vasoconstriction
leads to lower BP
Adverse drug reactions of ARBS high potassium, angioedema
prefix of cardiac glycosides "dig" ex: digoxin
MOA of cardiac glycosides block Na/K pump, indirectly changes the calcium
balance, leads to powerful contraction w/ HB
does not lower blood pressure, only HR
FYIs for cardiac glycosides measure HR, hold if <60bpm
sx of digoxin toxicity: anorexia, visual disturbance,
chest palpitations
Which of the following drugs may A and B- Torsemide and HCTZ lower serum
cause hypokalemia? potassium due to increased potassium excretion in
A) torsemide the kidneys
B) hydrochlorothiazide D) When entering the circulation, digoxin binds to
C) spironolactone sodium/potassium pumps which can also decrease
D) Digoxin OR increase potassium
https://quizlet.com/1172680943/wgu-d027-pathopharm-exam-updated-2026-questions-answers-with-100-correct-answers-graded-a-guaranteed-succ… 3/30
