CHEMOTHERAPY CERTIFICATION EXAM
QUESTIONS AND VERIFIED ANSWERS 2026
▶ Cisplatin (Planitol). Answer: -Alkylating agent
-nephrotoxic (IV hydration 2-3 L per day)
-severe N/V
-ovarian and testicular
▶ Cyclophosphamide (Cytoxin). Answer: -Alkylating agent)
-hemorrhagic cystitis (dysuria, hematuria, hemorrhage)
-DC treatment if hemorrhagic cystitis
-adequate hydration
▶ Oxaliplatin. Answer: -Alkylating agent
-irritant and vesicant, extra caution with the IV site
,-peripheral neuropathy is a dose-limiting side effect (exacerbated by cold
temperatures)
-avoid cold drinks and foods, wearing gloves and warm shoes
-avoid breathing cold air
▶ Intrathecal Chemotherapy. Answer: -injects chemo directly into the
subarachnoid space so it reaches the CNS
-Often used to treat leukemia and lymphoma that has spread to the CNS
since most IV chemo does not cross the blood-brain barrier
-only MTX and cytarabine via this route
-IT hydrocortisone is often given at the same time to reduce inflammation
-MUST be preservative free to avoid CNS irritation
▶ Chemotherapy-Induced N/V (CINV) Risk factors. Answer: -younger
-have a hx of low or no alcohol consumption
-are female
-hx of morning sickness
, -prone to motion sickness
-have had chemo previously
▶ Types of CINV. Answer: -Acute: occurring within 24 hours
-Delayed: from 24 hour - 5 days after
-Breakthrough: Occurring despite treatment
-Anticipatory: triggered by taste, odor, memories, visions, anxiety r/t chemo
-Refractory: occurring despite subsequent cycles when treatment failed in
earlier cycles
▶ Prevention/Treatment of hand foot syndrome. Answer: -limit exposure of
hands and feet to hot water
-take cool showers
-avoid exposure to sources of heat, such as using saunas or sitting in the
sun
-avoid activities that cause unnecessary force or friction on the hands or
feet, such as running or aerobics
QUESTIONS AND VERIFIED ANSWERS 2026
▶ Cisplatin (Planitol). Answer: -Alkylating agent
-nephrotoxic (IV hydration 2-3 L per day)
-severe N/V
-ovarian and testicular
▶ Cyclophosphamide (Cytoxin). Answer: -Alkylating agent)
-hemorrhagic cystitis (dysuria, hematuria, hemorrhage)
-DC treatment if hemorrhagic cystitis
-adequate hydration
▶ Oxaliplatin. Answer: -Alkylating agent
-irritant and vesicant, extra caution with the IV site
,-peripheral neuropathy is a dose-limiting side effect (exacerbated by cold
temperatures)
-avoid cold drinks and foods, wearing gloves and warm shoes
-avoid breathing cold air
▶ Intrathecal Chemotherapy. Answer: -injects chemo directly into the
subarachnoid space so it reaches the CNS
-Often used to treat leukemia and lymphoma that has spread to the CNS
since most IV chemo does not cross the blood-brain barrier
-only MTX and cytarabine via this route
-IT hydrocortisone is often given at the same time to reduce inflammation
-MUST be preservative free to avoid CNS irritation
▶ Chemotherapy-Induced N/V (CINV) Risk factors. Answer: -younger
-have a hx of low or no alcohol consumption
-are female
-hx of morning sickness
, -prone to motion sickness
-have had chemo previously
▶ Types of CINV. Answer: -Acute: occurring within 24 hours
-Delayed: from 24 hour - 5 days after
-Breakthrough: Occurring despite treatment
-Anticipatory: triggered by taste, odor, memories, visions, anxiety r/t chemo
-Refractory: occurring despite subsequent cycles when treatment failed in
earlier cycles
▶ Prevention/Treatment of hand foot syndrome. Answer: -limit exposure of
hands and feet to hot water
-take cool showers
-avoid exposure to sources of heat, such as using saunas or sitting in the
sun
-avoid activities that cause unnecessary force or friction on the hands or
feet, such as running or aerobics
