CHEMOTHERAPY ACTUAL EXAM
QUESTIONS AND COMPLETE STUDY GUIDE
2026
▶ Nadir. Answer: -point at which blood cell counts are at their lowest
following treatment
-typically, but not always, occurs 7-10 days after the cycle is administered
▶ Neutropenia. Answer: -ANC of less than 500/mm3 or
-less than 1000/mm3 with the expectation that the count will drop below
500 in the next 48 hours
▶ Neutopenia RF. Answer: -older than 65
-hx of neutropenia with previous chemo
-previous chemo or radiation
-hematologic malignancy, uncontrolled or advanced cancer, or lung cancer
▶ Neutropenic Fever. Answer: -temp of 38.3 or greater one time
,-temp of 38 lasting 1 hour
▶ Absolute Neutrophil Count. Answer: - (%segs + %bands) x (WBC) / 100
▶ Mucositis. Answer: -inflammation of the mucous membrane lining the
digestive tract from mouth to anus
-affects 40-100% of pts
▶ Stomatitis. Answer: -specifically inflammatory conditions of the mouth
▶ Xerostomia. Answer: -dryness of the mouth caused by damage to or
dysfunction of the salivary glands
▶ Hypersensitivity Reaction (HSR). Answer: -body mounts an
immunologic response to a foreign substance or antigen, resulting in local
tissue injury
▶ IgE-mediated. Answer: -immediate (within 5 minute) HSR, present like
classic allergic reactions
▶ T-Cell--Mediated. Answer: -Delayed hypersensitivity reactions, can
occur any time after the immediate hypersensitivity window, even days or
weeks
, ▶ Type 1 HSR early S/SX. Answer: -pruritus
-restlessness, agitation, anxiety, feeling of impending doom
-fever, flushing, chills
-urticaria (hives)
-maculopapular rash
-edema of hands, face, and feet
-N/V
-dyspnea, wheezing, bronchospasm
-hypotension, cyanosis
-circulatory and respiratory collapse
▶ Type IV HSR. Answer: -pneumonitis
-mucositis
-contact dermatitis
-granulomas
-Graph vs host disease
▶ Lesson 7: Cumulative Dose. Answer:
▶ Cumulative dose. Answer: total amount of one antineoplastic agent
given to the pt, adding up each time that the pt has received it
QUESTIONS AND COMPLETE STUDY GUIDE
2026
▶ Nadir. Answer: -point at which blood cell counts are at their lowest
following treatment
-typically, but not always, occurs 7-10 days after the cycle is administered
▶ Neutropenia. Answer: -ANC of less than 500/mm3 or
-less than 1000/mm3 with the expectation that the count will drop below
500 in the next 48 hours
▶ Neutopenia RF. Answer: -older than 65
-hx of neutropenia with previous chemo
-previous chemo or radiation
-hematologic malignancy, uncontrolled or advanced cancer, or lung cancer
▶ Neutropenic Fever. Answer: -temp of 38.3 or greater one time
,-temp of 38 lasting 1 hour
▶ Absolute Neutrophil Count. Answer: - (%segs + %bands) x (WBC) / 100
▶ Mucositis. Answer: -inflammation of the mucous membrane lining the
digestive tract from mouth to anus
-affects 40-100% of pts
▶ Stomatitis. Answer: -specifically inflammatory conditions of the mouth
▶ Xerostomia. Answer: -dryness of the mouth caused by damage to or
dysfunction of the salivary glands
▶ Hypersensitivity Reaction (HSR). Answer: -body mounts an
immunologic response to a foreign substance or antigen, resulting in local
tissue injury
▶ IgE-mediated. Answer: -immediate (within 5 minute) HSR, present like
classic allergic reactions
▶ T-Cell--Mediated. Answer: -Delayed hypersensitivity reactions, can
occur any time after the immediate hypersensitivity window, even days or
weeks
, ▶ Type 1 HSR early S/SX. Answer: -pruritus
-restlessness, agitation, anxiety, feeling of impending doom
-fever, flushing, chills
-urticaria (hives)
-maculopapular rash
-edema of hands, face, and feet
-N/V
-dyspnea, wheezing, bronchospasm
-hypotension, cyanosis
-circulatory and respiratory collapse
▶ Type IV HSR. Answer: -pneumonitis
-mucositis
-contact dermatitis
-granulomas
-Graph vs host disease
▶ Lesson 7: Cumulative Dose. Answer:
▶ Cumulative dose. Answer: total amount of one antineoplastic agent
given to the pt, adding up each time that the pt has received it
