RODAKS HEMATOLOGY CLINICAL PRINCIPLES
AND APPLICATIONS REVISION HANDBOOK
2026 HEMOSTASIS AND LABORATORY
ANALYSIS
◉ 2. A hemoglobin molecule is composed of:
a. One heme molecule and four globin chains
b. Ferrous iron, protoporphyrin IX, and a globin chain
c. Protoporphyrin IX and four globin chains
d. Four heme molecules and four globin chains. Answer: d. Four
heme molecules and four globin chains
◉ 3. Which of the following would NOT interfere with the result
when hemoglobin determination is performed by
thecyanmethemoglobin method?
a. Increased lipids
b. Elevated WBC count
c. Lyse-resistant RBCs
d. Fetal hemoglobin. Answer: d. Fetal hemoglobin
,◉ 4. Using Wright-Giemsa stain, the morphologic description of an
eccentric dark nuclei with deeply basophilic (blue)cytoplasm and a
prominent pale central Golgi apparatus best describes a(n):
A b. Basophil
B d. Plasma cell
C c. Lymphocyte
D a. Eosinophil. Answer: B d. Plasma cell
◉ 5. Which of the following is the best area to review or perform a
differential on a stained blood film?
A b. Red blood cells are mostly separated, with a fewoverlapping.
B a. Red blood cells are all overlapped in groups of three ormore.
C c. Red blood cells look flattened, with none touching.. Answer: A b.
Red blood cells are mostly separated, with a fewoverlapping.
◉ 6. What is the percent transferrin saturation for a patient with
total serum iron of 63 ug/dL and TIBC of 420 ug/dL ?
A c. 15%
B a. 6.7%
C b. 12%
,D d. 80%. Answer: A c. 15%
◉ 7. The transfer of iron from the enterocyte into the plasma is
REGULATED by:
A d. Hepcidin
B b. Ferroportin
C c. Hephaestin
D a. Transferrin. Answer: A d. Hepcidin
◉ 8. Which of the following is the most mature normoblast?
A c. Pronormoblast
B d. Polychromatic normoblast
C b. Basophilic normoblast
D a. Orthochromic normoblast. Answer: D a. Orthochromic
normoblast
◉ 9. Hypoxia stimulates RBC production by:
A c. Increasing the number of RBC mitoses
B a. Inducing more pluripotent stem cells into the erythroidlineage
C b. Stimulating EPO production by the kidney
, D d. Stimulating the production of fibronectin bymacrophages of the
bone marrow. Answer: C b. Stimulating EPO production by the
kidney
◉ 10. The "control center" of the cell is the:
A d. Microtubular system
B a. Nucleus
C b. Cytoplasm
D c. Membrane. Answer: B a. Nucleus
◉ 11. Which are the most common erythrocytic stages found in
normal marrow?
A a. Pronormoblasts
B d. Polychromatophilic and orthochromic normoblasts
C c. Basophilic and polychromatophilic normoblasts
D b. Pronormoblasts and basophilic normoblasts. Answer: B d.
Polychromatophilic and orthochromic normoblasts
◉ 12. Which of the following plays a role in iron sensing so as to
adjust iron absorption and recycling?
A b. Transferrin receptor 2
B a. Hepcidin
C c. Ferroportin. Answer: A b. Transferrin receptor 2
AND APPLICATIONS REVISION HANDBOOK
2026 HEMOSTASIS AND LABORATORY
ANALYSIS
◉ 2. A hemoglobin molecule is composed of:
a. One heme molecule and four globin chains
b. Ferrous iron, protoporphyrin IX, and a globin chain
c. Protoporphyrin IX and four globin chains
d. Four heme molecules and four globin chains. Answer: d. Four
heme molecules and four globin chains
◉ 3. Which of the following would NOT interfere with the result
when hemoglobin determination is performed by
thecyanmethemoglobin method?
a. Increased lipids
b. Elevated WBC count
c. Lyse-resistant RBCs
d. Fetal hemoglobin. Answer: d. Fetal hemoglobin
,◉ 4. Using Wright-Giemsa stain, the morphologic description of an
eccentric dark nuclei with deeply basophilic (blue)cytoplasm and a
prominent pale central Golgi apparatus best describes a(n):
A b. Basophil
B d. Plasma cell
C c. Lymphocyte
D a. Eosinophil. Answer: B d. Plasma cell
◉ 5. Which of the following is the best area to review or perform a
differential on a stained blood film?
A b. Red blood cells are mostly separated, with a fewoverlapping.
B a. Red blood cells are all overlapped in groups of three ormore.
C c. Red blood cells look flattened, with none touching.. Answer: A b.
Red blood cells are mostly separated, with a fewoverlapping.
◉ 6. What is the percent transferrin saturation for a patient with
total serum iron of 63 ug/dL and TIBC of 420 ug/dL ?
A c. 15%
B a. 6.7%
C b. 12%
,D d. 80%. Answer: A c. 15%
◉ 7. The transfer of iron from the enterocyte into the plasma is
REGULATED by:
A d. Hepcidin
B b. Ferroportin
C c. Hephaestin
D a. Transferrin. Answer: A d. Hepcidin
◉ 8. Which of the following is the most mature normoblast?
A c. Pronormoblast
B d. Polychromatic normoblast
C b. Basophilic normoblast
D a. Orthochromic normoblast. Answer: D a. Orthochromic
normoblast
◉ 9. Hypoxia stimulates RBC production by:
A c. Increasing the number of RBC mitoses
B a. Inducing more pluripotent stem cells into the erythroidlineage
C b. Stimulating EPO production by the kidney
, D d. Stimulating the production of fibronectin bymacrophages of the
bone marrow. Answer: C b. Stimulating EPO production by the
kidney
◉ 10. The "control center" of the cell is the:
A d. Microtubular system
B a. Nucleus
C b. Cytoplasm
D c. Membrane. Answer: B a. Nucleus
◉ 11. Which are the most common erythrocytic stages found in
normal marrow?
A a. Pronormoblasts
B d. Polychromatophilic and orthochromic normoblasts
C c. Basophilic and polychromatophilic normoblasts
D b. Pronormoblasts and basophilic normoblasts. Answer: B d.
Polychromatophilic and orthochromic normoblasts
◉ 12. Which of the following plays a role in iron sensing so as to
adjust iron absorption and recycling?
A b. Transferrin receptor 2
B a. Hepcidin
C c. Ferroportin. Answer: A b. Transferrin receptor 2
