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HESI Dosage Calculations Practice Questions | Nursing Study Guide with Answers and Rationales

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Prepare confidently for your HESI Exam with this comprehensive Dosage Calculations practice question guide designed to strengthen essential nursing math skills. This resource includes carefully selected practice questions, correct answers, and detailed rationales covering key topics such as oral and IV dosing, unit conversions, weight-based calculations, drip rates, and safe medication administration principles. Ideal for structured study and last-minute revision, it improves accuracy, enhances clinical reasoning, and builds confidence for success in HESI dosage calculation assessments.

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HESI Dosage Calculations
Practice Questions |
Nursing Study Guide with
Answers and Rationales |
Graded A+ | Guaranteed
Success



Updated 2026 Questions and Answers

100% Verified Exam Prep and Comprehensive Rationales
Included

, A client with cardiogenic shock weighs 220 lb and is 11.3
receiving dopamine at the rate of 3 mcg/kg/minute. The
solution strength available is dopamine 400 mg in 250 ml First, convert pounds to kg, 220 lb : X = 2.2 lb : 1 kg = 100 kg. Next, calculate the
of D5W. The nurse should set the infusion pump to deliver dosage per minute, 3 mcg/kg/min x 100 kg = 300 mcg/min. Convert mcg/min to
how many ml/hour? (Enter numeric value only. If rounding mcg/hour, 300 mcg/min x 60 min=18,000 mcg/hour. Convert mcg/hr to mg/hour,
is required, round to the nearest tenth.) 18,000 mcg/hr = 18.0 mg/hour. Calculate the rate, 400 mg : 250 ml = 18 mg : X ml
400X = 4500 X = 11.25 = 11.3 ml. So, 18 mg/11.3 ml should be infused at 11.3
ml/hour.


A client with hypertension who weighs 72.4 kg is receiving 3.5
an infusion of nitroprusside (Nipride) 50 mg in D5W 250 ml
at 75 ml/hour. How many mcg/kg/minute is the client Calculate the mg/hour infusing, 50 mg : 250 ml = X : 75 ml 250X = 3750 and X = 15
receiving? (Enter numeric value only. If rounding is mg/hour. Next, convert mg/hr to mcg/hour, 15 mg/hour = 1 mg / 1000 mcg = 15,000
required, round to the nearest tenth.) mcg/hour, then divide by 60 min = 250 mcg/minute. Lastly, 250 mcg/72.4 kg/min =
3.45 = 3.5 mcg/kg/minute.


A client who weighs 70 kg is receiving a dopamine solution 1.9
of 800 mg/500 ml normal saline at 5 ml/hour. How many
mcg/kg/minute is the client receiving? (Enter numeric value To change ml/hour to mcg/kg/minute, use the formula: desired rate (5 ml/hour) /
only. If rounding is required, round to the nearest tenth.) volume available (500 ml) x dose available (800 mg) = 8 mg/hour. Next, convert
milligrams/hour to mcg/kg/minute: mg (8) x 1000 / kg (70) / 60 minutes = 1.904 =
1.9 mcg/kg/minute.


A client is receiving an IV solution of sodium chloride 0.9% Convert grams to mg, 1 gram equals 1,000 mg. Using ratio and proportion - 1,000
(Normal Saline) 250 ml with amiodarone (Cordarone) 1 mg : 250 ml :: X mg : 1ml 250X= 1,000 so X = 4 mg/ml is the solution concentration
gram at 17 ml/hour. How many mg/minute of amiodarone of amiodarone. The infusion rate (ml/hour) x concentration (mg/ml) divided by 60
is infusing? (Enter numeric value only. If rounding is minutes/hour 17 ml/hour x 4 mg/ml = 68/60 = 1.13 = 1.1 mg/minute.
required, round to the nearest tenth.)


A client who weighs 176 pounds is receiving an IV infusion 100
with esmolol hydrochloride (Brevibloc) at 48 ml/hour. The
IV solution is labeled with the concentration of Brevibloc 10 Convert pounds to kg by dividing 176 pounds by 2.2 pounds = 80 kg. Convert the IV
mg/ml. How many mcg/kg/minute is the client receiving? concentration from mg to mcg. 1 mg : 1000 mcg :: 10 mg : 10,000 mcg. Infusion
(Enter numeric value only.) rate (48 ml/hour) x concentration (10,000 mcg/ml) divided by 60 minutes/hour x 80
kg = 48 x 10,000 divided by 60 x 80 = 480, = 100 mcg/kg/minute.


The nurse is preparing the change-of-shift report for a 95
client who has a 265 ml secondary infusion that was
started 2 hours ago at a rate of 85 ml/hour via an infusion 85 ml x 2 hours = 170 ml has infused. 265 ml (total amount to be infused) - 170 ml
pump. The nurse should report that how many ml remain (amount infused) = 95 ml remain to be infused.
to be infused by the on-coming nurse? (Enter numeric
value only.)


A male client receives a prescription for ondansetron 2
hydrochloride (Zofran) 4 mg IV to prevent postoperative
nausea after an inguinal hernia repair. The medication is Use ratio and proportion, 4 mg : X ml = 2 mg : 1 ml 2X = 4 X = 2
available in 2 mg/ml. How many ml should the nurse
administer? (Enter numeric value only.)


The nurse is preparing to administer Hepatitis B Vaccine, 1 or 0.5
Recombinant (Energix-B) 5 mcg IM to a school-aged child.
The vaccine is labeled, 10 mcg/ml. How many ml should Use ratio and proportion, 5 mcg : X ml :: 10 mcg : 1ml
the nurse administer? (Enter numeric value only. If 10X = 5 X = 0.5 ml
rounding is required, round to the nearest tenth).


A client's daily PO prescription for aripiprazole (Abilify) is 1
increased from 15 mg to 30 mg. The medication is
available in 15 mg tablets, and the client already received 30 mg (total dose) - 15 mg (dose already administered) = 15 mg that still needs to
one tablet today. How many additional tablets should the be administered. Using the Desired/Have formula: 15 mg/15 mg = 1 tablet
nurse administer so the client receives the total newly
prescribed dose for the day? (Enter numeric value only.)

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